ChemicalBook > CAS DataBase List > 7-Hydroxycoumarin

7-Hydroxycoumarin

Product Name
7-Hydroxycoumarin
CAS No.
93-35-6
Chemical Name
7-Hydroxycoumarin
Synonyms
UMBELLIFERONE;7-Hydroxycoumarine;Z-LIGUSTILIDE;SKIMMETIN;7-Hydroxy-2H-chromen-2-one;UMBELLIFERON;Dichrin A;7 HC;HYDRANGIN;Hydramgin
CBNumber
CB1854673
Molecular Formula
C9H6O3
Formula Weight
162.14
MOL File
93-35-6.mol
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7-Hydroxycoumarin Property

Melting point:
230 °C (dec.)(lit.)
Boiling point:
248.82°C (rough estimate)
Density 
1.2599 (rough estimate)
refractive index 
1.5380 (estimate)
storage temp. 
2-8°C
solubility 
dioxane: soluble
pka
7.11(at 25℃)
form 
Powder and Agglomerate
color 
Off-white to beige-brownish
PH Range
Non/ uorescence (6.5) to blue / uorescence (8.0)
Odor
develops odor of coumarin on heating
Water Solubility 
1 g/100 mL (100 ºC)
λmax
320nm
Merck 
14,9847
BRN 
127683
Major Application
Fluorescent brighteners, fungicides, cosmetics, antitrypanosomal, antileishmanial activities, antifungal, antibacterial, antiinflammatory, antiHIV, detection of microorganisms, treatment of impaired neurotransmission disorders, Alzheimer’s disease, vascular and lymphatic edema cancer, early diagnosis of stroke, dental material, drug-coated coronary stent system
InChIKey
ORHBXUUXSCNDEV-UHFFFAOYSA-N
LogP
1.580 (est)
CAS DataBase Reference
93-35-6(CAS DataBase Reference)
NIST Chemistry Reference
7-Hydroxycoumarin(93-35-6)
EPA Substance Registry System
Umbelliferone (93-35-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
GN6820000
HS Code 
29322980
Toxicity
LD50 intravenous in mouse: 450mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
93979
Product name
Umbelliferone
Purity
suitable for fluorescence indicator, ≥98.0% (HPLC)
Packaging
25g
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
54826
Product name
Umbelliferone
Purity
analytical standard
Packaging
50mg
Price
$140
Updated
2024/03/01
TCI Chemical
Product number
H0236
Product name
Umbelliferone
Purity
>98.0%(GC)
Packaging
5g
Price
$31
Updated
2024/03/01
TCI Chemical
Product number
H0236
Product name
Umbelliferone
Purity
>98.0%(GC)
Packaging
25g
Price
$60
Updated
2024/03/01
Alfa Aesar
Product number
L04082
Product name
7-Hydroxycoumarin, 98%
Packaging
25g
Price
$68.7
Updated
2024/03/01
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7-Hydroxycoumarin Chemical Properties,Usage,Production

Chemical Properties

Light Brownish Powder

Uses

A metabolite of Coumarin. The aglucon of skimmin. Present in many plants

Uses

antifungal, phytoalexin

Uses

7-Hydroxycoumarin is used as an intracellular pH sensitive fluorescent indicator & bloodbrain barrier probe. It is used as a sunscreen agent, and an optical brightener for textiles. It has also been used as a gain medium for dye lasers.

Uses

In sunscreen lotions and creams; as intracellular and pH sensitive fluorescent indicator and blood-brain barrier probe.

Definition

ChEBI: A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7.

General Description

Umbelliferone is a naturally occurring coumarin, present in a variety of medicinal plants from the Apiaceae (Umbelliferae) family and also in plants from other families such as mouse-ear hawkweed.

Purification Methods

It crystallises from water (m 232-232.2o) or EtOH (m 232o). It sublimes at 160o/0.001mm. Fluorescence: Em max 452nm/Exc 325nm in 50% EtOH. [Beilstein 18 H 27, 18 I 306, 18 II 16, 18 III/IV 294, 18/1 V 386.]

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7-Hydroxycoumarin Suppliers

Beckmann-Kenko GmbH
Tel
+49 4241 9308 88
Fax
+49 4241 9308 89
Email
info@beckmann-kenko.com
Country
Germany
ProdList
479
Advantage
62
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View Lastest Price from 7-Hydroxycoumarin manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
7-Hydroxycoumarin 93-35-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000kg
Release date
2024-03-19
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
7-Hydroxycoumarine 93-35-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99.7%
Supply Ability
200000kg
Release date
2024-04-23
Henan Fengda Chemical Co., Ltd
Product
7-Hydroxycoumarin 93-35-6
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-24

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