Scopoletin
- Product Name
- Scopoletin
- CAS No.
- 92-61-5
- Chemical Name
- Scopoletin
- Synonyms
- Scopoletol;6-Methoxy-7-hydroxycoumarin;7-HYDROXY-6-METHOXY-2H-CHROMEN-2-ONE;6-METHOXYCOUMARIN;6-Methylesculetin;7-HYDROXY-6-METHOXY-2H-1-BENZOPYRAN-2-ONE;Baogongteng B;GELSEMINIC ACID;CHRYSATROPIC ACID;7-HYDROXY-5-METHOXYCOUMARIN
- CBNumber
- CB5265273
- Molecular Formula
- C10H8O4
- Formula Weight
- 192.17
- MOL File
- 92-61-5.mol
Scopoletin Property
- Melting point:
- 203-205 °C (lit.)
- Boiling point:
- 288.14°C (rough estimate)
- Density
- 1.2932 (rough estimate)
- refractive index
- 1.5430 (estimate)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Sightly, Heated), Ethyl Acetate (Slightly, Heated), Methanol (Slightly, Heated)
- pka
- 7.91±0.20(Predicted)
- form
- Crystalline Powder
- color
- Beige
- Water Solubility
- Slightly soluble
- Merck
- 14,8408
- BRN
- 156296
- InChIKey
- RODXRVNMMDRFIK-UHFFFAOYSA-N
- LogP
- 1.280 (est)
- CAS DataBase Reference
- 92-61-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 7-Hydroxy-6-methoxy-2h-1-benzopyran-2-one(92-61-5)
- EPA Substance Registry System
- Scopoletin (92-61-5)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 2
- RTECS
- GN6930000
- HS Code
- 29322090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PHL89516
- Product name
- Scopoletin
- Purity
- phyproof? Reference Substance
- Packaging
- 50MG
- Price
- $407
- Updated
- 2024/03/01
- Product number
- 38332
- Product name
- Scopoletin
- Purity
- analytical standard
- Packaging
- 10mg
- Price
- $132
- Updated
- 2024/03/01
- Product number
- 1610090
- Product name
- Scopoletin
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 20mg
- Price
- $229.8
- Updated
- 2024/03/01
- Product number
- S0367
- Product name
- Scopoletin
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 100mg
- Price
- $107
- Updated
- 2024/03/01
- Product number
- S0367
- Product name
- Scopoletin
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $649
- Updated
- 2024/03/01
Scopoletin Chemical Properties,Usage,Production
Chemical Properties
Crystalline Solid
Uses
Scopoletin is the aglucone of Scopolin. Used for cosmetics, topical formulations, and foods. Dyes and metabolites.
Definition
ChEBI: A hydroxycoumarin that is umbelliferone bearing a methoxy substituent at position 6.
benefits
Scopoletin is a coumarin synthesized by diverse medicinal and edible plants, which plays a vital role as a therapeutic and chemopreventive agent in the treatment of a variety of diseases. Scopoletin is indicated to have antimicrobial, anticancer, anti-inflammation, anti-angiogenesis, anti-oxidation, antidiabetic, antihypertensive, hepatoprotective, and neuroprotective properties and immunomodulatory effects in both in vitro and in vivo experimental trials. In addition, it is an inhibitor of various enzymes, including choline acetyltransferase, acetylcholinesterase, and monoamine oxidase.
Synthesis Reference(s)
The Journal of Organic Chemistry, 27, p. 3083, 1962 DOI: 10.1021/jo01056a023
General Description
Scopoletin is a coumarin compound and pharmacologically active chemical that is found in various plant species.
Biochem/physiol Actions
Scopoletin significantly increases activity of lipoprotein lipase in adipocytes by promoting transcription of the LPL gene. It also partially reverses inhibition of LPL by TNF-α.
Purification Methods
Crystallise it from water, acetic acid or *C6H6/MeOH. It is dimorphic with a second m at 193-195o. It sublimes at 120-130o/12mm. [Beilstein 18 H 99, 18 I 348, 18 II 68, 18 III/IV 1323, 18/3 V 203.]
Scopoletin Preparation Products And Raw materials
Raw materials
Preparation Products
Scopoletin Suppliers
- Tel
- 182-24028459 18224018291
- Fax
- QQ137193152
- 3004072879@qq.com
- Country
- China
- ProdList
- 1195
- Advantage
- 58
- Tel
- 028-85370565-229 18080489829
- 3004654993@qq.com
- Country
- China
- ProdList
- 8902
- Advantage
- 60
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 94657
- Advantage
- 76
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3572
- Advantage
- 66
- Tel
- +86-21-20908456
- Fax
- 021-58180499
- sales@BioChemBest.com
- Country
- China
- ProdList
- 6005
- Advantage
- 61
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 010-89508211 18501085097
- Fax
- 010-89508210
- sales.bj@hwrkchemical.com
- Country
- China
- ProdList
- 8418
- Advantage
- 55
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44688
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- sales@capotchem.com
- Country
- China
- ProdList
- 18207
- Advantage
- 66
View Lastest Price from Scopoletin manufacturers
- Product
- Scopoletin 92-61-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-06
- Product
- Scopoletin 92-61-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-08-24
- Product
- Scopoletin 92-61-5
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-10-09