ChemicalBook > CAS DataBase List > (S)-(+)-TETRAHYDROFURFURYL ALCOHOL

(S)-(+)-TETRAHYDROFURFURYL ALCOHOL

Product Name
(S)-(+)-TETRAHYDROFURFURYL ALCOHOL
CAS No.
57203-01-7
Chemical Name
(S)-(+)-TETRAHYDROFURFURYL ALCOHOL
Synonyms
102205;(2S)-oxolan-2-yl]methanol;(S)-TETRAHYDROFURFURYLALCOHOL;(S)-(+)-TETRAHYDROFURFURYL ALCOHOL;2-FuranMethanol, tetrahydro-, (2S)-;(R)-(-)-2-(Hydroxymethyl)tetrahydrofuran;(R)-(-)-2-(Hydroxymethyl)tetrahydrofurane;(2S)-(+)-2-(Hydroxymethyl)tetrahydrofuran;(S)-(+)-TETRAHYDROFURFURYL ALCOHOL ISO 9001:2015 REACH;(2S)-(+)-(Tetrahydrofur-2-yl)methanol, (S)-(+)-Tetrahydrofurfuryl alcohol
CBNumber
CB0448756
Molecular Formula
C5H10O2
Formula Weight
102.13
MOL File
57203-01-7.mol
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(S)-(+)-TETRAHYDROFURFURYL ALCOHOL Property

Boiling point:
176.8±8.0 °C(Predicted)
Density 
1.038±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
liquid
pka
14.44±0.10(Predicted)
color 
Clear, colourless
CAS DataBase Reference
57203-01-7
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Safety

HS Code 
2932990090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
T294085
Product name
(S)-(Tetrahydrofuran-2-yl)methanol
Packaging
250mg
Price
$195
Updated
2021/12/16
TRC
Product number
T294085
Product name
(S)-(Tetrahydrofuran-2-yl)methanol
Packaging
500mg
Price
$360
Updated
2021/12/16
Apolloscientific
Product number
OR40670
Product name
(2S)-(+)-2-(Hydroxymethyl)tetrahydrofuran
Purity
96%
Packaging
250mg
Price
$93
Updated
2021/12/16
SynQuest Laboratories
Product number
2H01-1-04
Product name
(2S)-(+)-2-(Hydroxymethyl)tetrahydrofuran
Packaging
250mg
Price
$103
Updated
2021/12/16
Apolloscientific
Product number
OR40670
Product name
(2S)-(+)-2-(Hydroxymethyl)tetrahydrofuran
Purity
96%
Packaging
1g
Price
$218
Updated
2021/12/16
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(S)-(+)-TETRAHYDROFURFURYL ALCOHOL Chemical Properties,Usage,Production

Uses

(S)-(Tetrahydrofuran-2-yl)methanol is used during aminopyrrolopyrimidine derivatives preparation and IGF-1R inhibition in tumors.

Synthesis

87392-05-0

97-99-4

Under argon protection, (R)-tetrahydrofuran-2-carboxylic acid (2 g, 17.22 mmol) was dissolved in 20 mL of tetrahydrofuran (THF) and the reaction flask was cooled in an ice bath. Borane-dimethyl sulfide complex (BH3-SMe2, 2M THF solution, 10 mL, 20.0 mmol) was slowly added to the reaction solution over 10 min. After removing the ice bath, the reaction mixture was stirred at room temperature for 1 hour. Subsequently, the reaction mixture was again cooled in an ice bath and methanol was slowly added until no gas escaped. Finally, the reaction solution was concentrated under reduced pressure to afford the target product tetrahydrofurfuryl alcohol as an oil (1 g, 60% yield). The product was characterized by 1H NMR (300 MHz, CDCl3): δ 1.55-1.70 (m, 1H), 1.72-1.98 (m, 3H), 3.35-4.00 (m, 6H).

References

[1] European Journal of Organic Chemistry, 2001, # 23, p. 4537 - 4542
[2] Patent: WO2016/16238, 2016, A1. Location in patent: Page/Page column 184
[3] Patent: WO2017/134188, 2017, A1. Location in patent: Page/Page column 48; 49
[4] Journal of Medicinal Chemistry, 1995, vol. 38, # 15, p. 2830 - 2841
[5] Journal of Organic Chemistry, 1997, vol. 62, # 2, p. 242 - 243

(S)-(+)-TETRAHYDROFURFURYL ALCOHOL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (S)-(+)-TETRAHYDROFURFURYL ALCOHOL manufacturers

Career Henan Chemical Co
Product
(S)-(+)-TETRAHYDROFURFURYL ALCOHOL 57203-01-7
Price
US $2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg, 5kg ,50kg
Release date
2020-01-08

57203-01-7, (S)-(+)-TETRAHYDROFURFURYL ALCOHOLRelated Search:


  • 2-FuranMethanol, tetrahydro-, (2S)-
  • (R)-(-)-2-(Hydroxymethyl)tetrahydrofuran
  • (R)-(-)-2-(Hydroxymethyl)tetrahydrofurane
  • (S)-TETRAHYDROFURFURYLALCOHOL
  • (2S)-(+)-(Tetrahydrofur-2-yl)methanol, (S)-(+)-Tetrahydrofurfuryl alcohol
  • (2S)-(+)-2-(Hydroxymethyl)tetrahydrofuran
  • (S)-(+)-TETRAHYDROFURFURYL ALCOHOL
  • (2S)-oxolan-2-yl]methanol
  • 102205
  • (S)-(+)-TETRAHYDROFURFURYL ALCOHOL ISO 9001:2015 REACH
  • 57203-01-7
  • Alcohols, Hydroxy Esters and Derivatives
  • Chiral Compounds