CNICIN

Product Name: CNICIN
CAS No.: 24394-09-0
Chemical Name: CNICIN
Synonyms: CNICIN;CYNISIN;cnicine;CENTAURIN;Cnicin-RM;Aids104627;Aids-104627;-lactone,8-(3,4-dihydroxy-2-methylenebutyrate);2,3,3a,4,5,8,9,11a-octahydro-10-(hydroxymethyl)-6-methyl-3-methylene-2-oxocyclodeca[b]furan-4-yl 3,4-dihydroxy-2-methylenebutyrate;3,4-Dihydroxy-2-methylenebutanoic acid 2,3,3A,4,5,8,9,11A-octahydro-10-(hydroxymethyl)-6-methyl-3-methylene-2-oxocyclodeca[B]furan-4-yl ester
CBNumber: CB0456861
Molecular Formula: C20H26O7
Formula Weight: 378.42
MOL File: 24394-09-0.mol

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CNICIN Property

Melting point:: 142-143°C
alpha: D20 +158° (c = 2.3 in ethanol)
Boiling point:: 622.3±55.0 °C(Predicted)
Density: 1.27±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.: 2-8°C
solubility: Acetonitrile: Soluble
Methanol: Soluble
form: Solid
pka: 12.77±0.20(Predicted)
color: White to off-white
LogP: 2.320 (est)

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Safety

Safety Statements: 22-24/25
Toxicity: mouse,LD50,oral,452mg/kg (452mg/kg),Planta Medica. Vol. 53, Pg. 247, 1987.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FC65567
Product name: Cynisin
Packaging: 1mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC65567
Product name: Cynisin
Packaging: 2mg
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC65567
Product name: Cynisin
Packaging: 5mg
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC65567
Product name: Cynisin
Packaging: 10mg
Price: $380
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HBL0000113
Product name: CNICIN
Purity: 95.00%
Packaging: 5MG
Price: $500.39
Updated: 2021/12/16

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CNICIN Chemical Properties,Usage,Production

Uses

(+)-Cnicin is a useful research chemical exhibiting antifungal activity of sesquiterpene lactones from Centaurea species.

References

[1] ANKE BACHELIER Christian D K Ralf Mayer. Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA[J]. Bioorganic & Medicinal Chemistry Letters, 2006, 16 21: Pages 5605-5609. DOI: 10.1016/j.bmcl.2006.08.021
[2] VASILIKI SAROGLOU. Sesquiterpene Lactones from Centaurea spinosa and Their Antibacterial and Cytotoxic Activities[J]. Journal of Natural Products , 2005, 68 9: 1404-1407. DOI: 10.1021/np058042u
[3] TUGCE DEMIROZ . Anti-inflammatory properties of Centaurea calolepis Boiss. and cnicin against Macrovipera lebetina obtusa (Dwigubsky, 1832) and Montivipera xanthina (Gray, 1849) venoms in rat[J]. Toxicon, 2018, 152: Pages 37-42. DOI: 10.1016/j.toxicon.2018.07.016

CNICIN Preparation Products And Raw materials

Raw materials

Preparation Products

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CNICIN Suppliers

China 28 France 1 Germany 2 United Kingdom 5 United States 6 Global 42

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Biyu Biotechnology (Shanghai) Co., ltd

Tel: 021-26018599
Country: China
ProdList: 270
Advantage: 56

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9751
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Aktin Chemicals, Inc.

Tel: 028-85159085
Email: info@aktinchem.com
Country: China
ProdList: 1860
Advantage: 58

24394-09-0, CNICINRelated Search:

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cnicine

-lactone,8-(3,4-dihydroxy-2-methylenebutyrate)

CYNISIN

CNICIN

CENTAURIN

2,3,3a,4,5,8,9,11a-octahydro-10-(hydroxymethyl)-6-methyl-3-methylene-2-oxocyclodeca[b]furan-4-yl 3,4-dihydroxy-2-methylenebutyrate

(3R)-3,4-Dihydroxy-2-methylenebutyric acid (3aR,4S,6E,10Z,11aR)-2,3,3a,4,5,8,9,11a-octahydro-10-(hydroxymethyl)-6-methyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester

3,4-Dihydroxy-2-methylenebutanoic acid 2,3,3A,4,5,8,9,11A-octahydro-10-(hydroxymethyl)-6-methyl-3-methylene-2-oxocyclodeca[B]furan-4-yl ester

Aids104627

Aids-104627

Butanoic acid, 3,4-dihydroxy-2-methylene-, (3aR,4S,6E,10Z,11aR)-2,3,3a,4,5,8,9,11a-octahydro-10-(hydroxymethyl)-6-methyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (3R)-

Cnicin-RM

24394-09-0

C20H26O7

Heterocycles