3,5-Dihydroxybenzyl alcohol

ChemicalBook > CAS DataBase List > 3,5-Dihydroxybenzyl alcohol

3,5-Dihydroxybenzyl alcohol

Product Name: 3,5-Dihydroxybenzyl alcohol
CAS No.: 29654-55-5
Chemical Name: 3,5-Dihydroxybenzyl alcohol
Synonyms: 5-(hydroxymethyl)benzene-1,3-diol;2-(hydroxymethyl)benzene-1,4-diol;3,5-Dihydroxybenzyl;RARECHEM AL BD 0252;3,5-dihydroxy Methanol;3,5-Dihydroxybenzyl alc;hydroxyMethyl)resorcinol;3-dihidroxybenzylalcohol;3，5-dihidroxybenzylalcohol;3,5-dihydroxy-benzylalcoho
CBNumber: CB0458906
Molecular Formula: C7H8O3
Formula Weight: 140.14
MOL File: 29654-55-5.mol

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3,5-Dihydroxybenzyl alcohol Property

Melting point:: 182-186 °C (dec.) (lit.)
Boiling point:: 216.62°C (rough estimate)
Density: 1.2127 (rough estimate)
refractive index: 1.4638 (estimate)
storage temp.: Inert atmosphere,2-8°C
solubility: Soluble in DMSO, methanol.
form: Crystalline Powder
pka: 9.23±0.10(Predicted)
color: Off-white to beige-pink or gray
BRN: 2326351
InChI: InChI=1S/C7H8O3/c8-4-5-1-6(9)3-7(10)2-5/h1-3,8-10H,4H2
InChIKey: NGYYFWGABVVEPL-UHFFFAOYSA-N
SMILES: C1(O)=CC(CO)=CC(O)=C1
CAS DataBase Reference: 29654-55-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: DO1400000
HS Code: 29052900
Toxicity: mouse,LD50,intravenous,750mg/kg (750mg/kg),British Journal of Pharmacology and Chemotherapy. Vol. 22, Pg. 221, 1964.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 396206
Product name: 3,5-Dihydroxybenzyl alcohol
Purity: 99%
Packaging: 5g
Price: $67.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 396206
Product name: 3,5-Dihydroxybenzyl alcohol
Purity: 99%
Packaging: 25g
Price: $107.2
Updated: 2024/03/01

TCI Chemical

Product number: D2656
Product name: 3,5-Dihydroxybenzyl Alcohol
Purity: >97.0%(GC)
Packaging: 5g
Price: $104
Updated: 2024/03/01

TCI Chemical

Product number: D2656
Product name: 3,5-Dihydroxybenzyl Alcohol
Purity: >97.0%(GC)
Packaging: 25g
Price: $508
Updated: 2024/03/01

Alfa Aesar

Product number: B25248
Product name: 3,5-Dihydroxybenzyl alcohol, 98%
Packaging: 1g
Price: $31.7
Updated: 2023/06/20

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3,5-Dihydroxybenzyl alcohol Chemical Properties,Usage,Production

Description

3,5-dihydroxybenzyl alcohol: a kind of critical medicine intermediate and chemical intermediate
3,5-Dihydroxybenzyl alcohol is a colourless product with a melting point of 182~186℃. It is soluble in water, ethanol, ether, THF and other polar solvents. This compound is a vital pharmaceutical and chemical intermediate and an essential raw material for organic synthesis. It can be used as a raw material to prepare pseudo-choleretic drugs with intellectual property rights in my country, such as pseudo-amyloid, bonicon, bromoprim, and resveratrol. It has antibacterial, anti-inflammatory, anti-tumour, antioxidant, anti-shock, and coronary heart disease prevention and treatment biological activities. It is mainly isolated from Veratrum ussuri and Veratrum hairy spike produced in Northeast China; it can also be used to synthesize pharmaceutical intermediates such as 3,5-dihydroxybenzaldehyde and 3,5-dihydroxybenzoyl ethyl ketone, and can also be used as an additive in the field of fine chemicals such as daily chemicals.

Chemical Properties

White to light yellow crystal powder

Uses

3,5-Dihydroxybenzyl Alcohol is a used as a dendrimer building block.

Uses

3,5-Dihydroxybenzyl alcohol may be used as monomer for the synthesis of a series of monodisperse dendritic polyether macromolecules.?It may be employed in the synthesis of dimethylsilyl linked dihydroxybenzyl alcohol based dendrimers.

General Description

Aggregation behavior of 3,5-dihydroxybenzyl alcohol based dendritic polymers has been investigated by dynamic light scattering and transmission electron microscopy. Preparation of dendritic polyether macromolecules based on 3, 5-dihydroxybenzyl alcohol building block and having carboxylate groups as chain-ends has been described.

Synthesis

Preparation of 3,5-dihydroxybenzyl alcohol: Add 50mL THF to a 250mL three-necked flask, add 3.15g (0.082mol) NaBH, 2.38g (0.01mol) 3,5-Diacetoxybenzoic acid, control the temperature at 0 degrees in an ice-water bath, slowly drop 60ml THF solution containing 9g (0.036mol) I2, and then add 4.76g (0.02mol) of the product from the previous step after the dropwise addition, heat to reflux, and track the reaction with a plate. After the reaction is completed, concentrate to dryness under reduced pressure, add 100mL saturated NaHCO solution, extract with ether, combine the organic layers, dry with anhydrous magnesium sulfate, filter, concentrate, and recrystallize with hot water to obtain 3.5g white crystals with a yield of 83.2%.

3,5-Dihydroxybenzyl alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

3,5-Dibenzyloxybenzyl alcohol 3,5-Dibenzyloxybenzaldehyde 3,5-BIS(BENZYLOXY)BENZYL BROMIDE

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View Lastest Price from 3,5-Dihydroxybenzyl alcohol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 3,5-Dihydroxybenzyl alcohol 29654-55-5
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 500KGS
Release date: 2021-11-08

Hebei Weibang Biotechnology Co., Ltd

Product: 3,5-Dihydroxybenzyl alcohol 29654-55-5
Price: US $10.00-8.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2022-09-16

Hebei Weibang Biotechnology Co., Ltd

Product: 3,5-Dihydroxybenzyl alcohol 29654-55-5
Price: US $10.00-8.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2022-09-16

29654-55-5, 3,5-Dihydroxybenzyl alcoholRelated Search:

m-Anisyl alcohol 3-Hydroxybenzyl alcohol 4-Hydroxybenzyl alcohol Resorcinol Ethyl acetate 2-Hydroxybenzyl alcohol Benzyl alcohol 3,5-Dihydroxybenzoic acid Tris(hydroxymethyl)nitromethane Benzhydrol 3,5-Dihydroxybenzaldehyde Methyl 3,5-dihydroxybenzoate 3,4,5-Trimethoxybenzyl alcohol 3,4,5-Trimethoxy benzoic acid Propyl gallate 3,5-Dibenzyloxybenzyl alcohol 3-Hydroxy-4,5-dimethoxybenzoic acid Gallic acid monohydrate

3，5-dihidroxybenzylalcohol

3,5-DihydroxyBenzylAlcohol99%

3,5-dihydroxy-benzylalcoho

(3,5-Dihydroxyphenyl)methanol

3,5-Dihydroxybenzyl

1,3-Benzenediol, 5-(hydroxymethyl)-

3,5-DIHYDOXYBENZENEMETHANOL

5-(hydroxymethyl)benzene-1,3-diol

3,5-DIHYDROXYBENZYL ALCOHOL 98+%

3,5-dihydroxy Methanol

3,5-Dihydroxybenzyl alc

3,5-Dihydroxybenzyl alcohol, (3,5-Dihydroxyphenyl)methyl alcohol, 5-(Hydroxymethyl)resorcinol

3,5-Dihydroxybenzyl alcohol, 98% 5GR

1,3-Dihydroxy-5-(hydroxyMethyl)benzene

hydroxyMethyl)resorcinol

RARECHEM AL BD 0252

5-(HYDROXYMETHYL)RESORCINOL

5-(HYDROXYMETHYL)-1,3-BENZENEDIOL

3,5-DIHYDROXYBENZYL ALCOHOL

3,5-Dihydroxybenzenemethanol

3-dihidroxybenzylalcohol

2-(hydroxymethyl)benzene-1,4-diol

3,5-DihydroxybenzylAlcohol&gt

3,5-Dihydroxybenzyl alcohol, 98%, for synthesis

29654-55-5

296454-55-5

29654-55-4

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