DESMETHYL LOPERAMIDE
- Product Name
- DESMETHYL LOPERAMIDE
- CAS No.
- 66164-07-6
- Chemical Name
- DESMETHYL LOPERAMIDE
- Synonyms
- dLop;R 20905;DESMETHYL LOPERAMIDE;N-Desmethyl Loperamid;N-Desmethyl Loperamide;Desmethylloperamide D5;Desmethyl loperamide HCl;4-(4-Chlorophenyl)-4-hydroxy-N-methyl-a,a-diphenyl-1-piperidinebutanamide;4-(4-Chlorophenyl)-4-hydroxy-N-Methyl-α,α-diphenyl-1-piperidinebutanaMide;1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-
- CBNumber
- CB0462831
- Molecular Formula
- C28H31ClN2O2
- Formula Weight
- 463.01
- MOL File
- 66164-07-6.mol
DESMETHYL LOPERAMIDE Property
- Melting point:
- 219-221?C
- Boiling point:
- 678.3±55.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMF: 2 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 1 mg/ml
- form
- A crystalline solid
- pka
- 13.85±0.20(Predicted)
Safety
- HS Code
- 9999999999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 16126
- Product name
- N-Desmethyl-loperamide
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $184
- Updated
- 2024/03/01
- Product number
- 16126
- Product name
- N-Desmethyl-loperamide
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $330
- Updated
- 2024/03/01
- Product number
- 16126
- Product name
- N-Desmethyl-loperamide
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $984
- Updated
- 2024/03/01
- Product number
- D291840
- Product name
- N-DesmethylLoperamide
- Packaging
- 2mg
- Price
- $365
- Updated
- 2021/12/16
- Product number
- 008596
- Product name
- N-Desmethyl Loperamide
- Packaging
- 1mg
- Price
- $475
- Updated
- 2021/12/16
DESMETHYL LOPERAMIDE Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
A metabolite of Loperamide; a new and improved PET radiotracer for imaging P-gp function
Uses
Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. N-Desmethyl-loperamide (dLop) is a major metabolite of loperamide. Like loperamide, dLop is a substrate of the ATP-dependent efflux transporter, P-glycoprotein. As a result, both the parent compound and the metabolite display restricted passage through the blood-brain barrier. dLop in biological samples can be analyzed by a variety of methods.
Definition
ChEBI: A monocarboxylic acid amide that is the methylamide of 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanoic acid.
DESMETHYL LOPERAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
DESMETHYL LOPERAMIDE Suppliers
View Lastest Price from DESMETHYL LOPERAMIDE manufacturers
- Product
- DESMETHYL LOPERAMIDE 66164-07-6
- Price
- US $0.00/gram
- Min. Order
- 1gram
- Purity
- 99%
- Supply Ability
- 10kg
- Release date
- 2022-02-17