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DESMETHYL LOPERAMIDE

Product Name
DESMETHYL LOPERAMIDE
CAS No.
66164-07-6
Chemical Name
DESMETHYL LOPERAMIDE
Synonyms
dLop;R 20905;DESMETHYL LOPERAMIDE;N-Desmethyl Loperamid;N-Desmethyl Loperamide;Desmethylloperamide D5;Desmethyl loperamide HCl;4-(4-Chlorophenyl)-4-hydroxy-N-methyl-a,a-diphenyl-1-piperidinebutanamide;4-(4-Chlorophenyl)-4-hydroxy-N-Methyl-α,α-diphenyl-1-piperidinebutanaMide;1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-
CBNumber
CB0462831
Molecular Formula
C28H31ClN2O2
Formula Weight
463.01
MOL File
66164-07-6.mol
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DESMETHYL LOPERAMIDE Property

Melting point:
219-221?C
Boiling point:
678.3±55.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMF: 2 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 1 mg/ml
form 
A crystalline solid
pka
13.85±0.20(Predicted)
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Safety

HS Code 
9999999999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16126
Product name
N-Desmethyl-loperamide
Purity
≥98%
Packaging
500μg
Price
$184
Updated
2024/03/01
Cayman Chemical
Product number
16126
Product name
N-Desmethyl-loperamide
Purity
≥98%
Packaging
1mg
Price
$330
Updated
2024/03/01
Cayman Chemical
Product number
16126
Product name
N-Desmethyl-loperamide
Purity
≥98%
Packaging
5mg
Price
$984
Updated
2024/03/01
TRC
Product number
D291840
Product name
N-DesmethylLoperamide
Packaging
2mg
Price
$365
Updated
2021/12/16
Usbiological
Product number
008596
Product name
N-Desmethyl Loperamide
Packaging
1mg
Price
$475
Updated
2021/12/16
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DESMETHYL LOPERAMIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A metabolite of Loperamide; a new and improved PET radiotracer for imaging P-gp function

Uses

Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. N-Desmethyl-loperamide (dLop) is a major metabolite of loperamide. Like loperamide, dLop is a substrate of the ATP-dependent efflux transporter, P-glycoprotein. As a result, both the parent compound and the metabolite display restricted passage through the blood-brain barrier. dLop in biological samples can be analyzed by a variety of methods.

Definition

ChEBI: A monocarboxylic acid amide that is the methylamide of 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanoic acid.

DESMETHYL LOPERAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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DESMETHYL LOPERAMIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Artis Chemistry (Shanghai) Co. Ltd.
Tel
86-21-60936353
Fax
86-21-60936352
Country
China
ProdList
335
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57423
Advantage
58
Hefei Molake Biotechnology Co., Ltd.
Tel
0551-66336380 18956014586
Fax
055166336380
Email
983438788@qq.com
Country
China
ProdList
2139
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
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View Lastest Price from DESMETHYL LOPERAMIDE manufacturers

Zhejiang J&C Biological Technology Co.,Limited
Product
DESMETHYL LOPERAMIDE 66164-07-6
Price
US $0.00/gram
Min. Order
1gram
Purity
99%
Supply Ability
10kg
Release date
2022-02-17

66164-07-6, DESMETHYL LOPERAMIDERelated Search:


  • DESMETHYL LOPERAMIDE
  • 4-(4-Chlorophenyl)-4-hydroxy-N-methyl-a,a-diphenyl-1-piperidinebutanamide
  • N-Desmethyl Loperamide
  • R 20905
  • Desmethyl loperamide HCl
  • Desmethylloperamide D5
  • 4-(4-Chlorophenyl)-4-hydroxy-N-Methyl-α,α-diphenyl-1-piperidinebutanaMide
  • 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-
  • dLop
  • N-Desmethyl Loperamid
  • 66164-07-6
  • C28H31ClN2O2HCl
  • C28H31ClN2O2
  • Amines
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals