ChemicalBook > CAS DataBase List > N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide

N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide

Product Name
N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide
CAS No.
1011244-68-0
Chemical Name
N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide
Synonyms
TFAP;CS-2896;COX-1 Inhibitor IV;COX-1 Inhibitor IV(TFAP);N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide;N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide;Benzamide, N-(5-amino-2-pyridinyl)-4-(trifluoromethyl)-;Cyclooxygenase,COX,inhibit,Endogenous Metabolite,TFAP,Inhibitor
CBNumber
CB04663492
Molecular Formula
C13H10F3N3O
Formula Weight
281.23
MOL File
1011244-68-0.mol
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N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide Property

Boiling point:
360.8±42.0 °C(Predicted)
Density 
1.425±0.06 g/cm3(Predicted)
storage temp. 
+2C to +8C
solubility 
DMF: 5mg/mL; DMSO: 10mg/mL; Ethanol: 10mg/mL; Ethanol:PBS (pH 7.2) (1:4): 0.2mg/mL
form 
Off-white solid
pka
11.02±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26745
Product name
TFAP
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
26745
Product name
TFAP
Packaging
25mg
Price
$456
Updated
2024/03/01
Cayman Chemical
Product number
26745
Product name
TFAP
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
26745
Product name
TFAP
Packaging
10mg
Price
$199
Updated
2024/03/01
ChemScene
Product number
CS-0063093
Product name
TFAP
Purity
99.97%
Packaging
5mg
Price
$90
Updated
2021/12/16
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N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide Chemical Properties,Usage,Production

Biological Activity

TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a cell-permeable and selective cyclooxygenase-1 (COX-1) inhibitor with IC50 of 0.8 μM.

in vitro

TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC 50 of 0.8 μM, while that against COX-2 is over 200 μM.

target

TargetValue
COX-1
(Cell-free assay)		 0.8 μM

N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide Suppliers

China 51 India 1 United States 8 Global 60
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58

1011244-68-0, N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamideRelated Search:


  • N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide
  • TFAP
  • CS-2896
  • COX-1 Inhibitor IV(TFAP)
  • COX-1 Inhibitor IV
  • N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide
  • Benzamide, N-(5-amino-2-pyridinyl)-4-(trifluoromethyl)-
  • Cyclooxygenase,COX,inhibit,Endogenous Metabolite,TFAP,Inhibitor
  • 1011244-68-0