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Rp-8-bromo-Cyclic AMPS (sodium salt)

Product Name
Rp-8-bromo-Cyclic AMPS (sodium salt)
CAS No.
925456-59-3
Chemical Name
Rp-8-bromo-Cyclic AMPS (sodium salt)
Synonyms
Rp-isomer;Rp-8-bromo-cAMPS;8-Bromoadenosine 3';Rp-8-bromo-Cyclic AMPS;5'-cyclic monophosphorothioate;Rp-8-bromo-Cyclic AMPS (sodium salt);8-bromo-adenosinecyclic3',5'-[hydrogen[P(R)]-phosphorothioate],monosodiumsalt;RP-8-BR-CAMPS;8-BROMOADENOSINE 3';5'-CYCLIC MONOPHOSPHOROTHIOATE; RP-ISOMER;RP-8-BROMO-CAMPS;925456-59-3
CBNumber
CB04666286
Molecular Formula
C10H12BrN5NaO5PS
Formula Weight
448.16
MOL File
925456-59-3.mol
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Rp-8-bromo-Cyclic AMPS (sodium salt) Property

storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 0.5 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21584
Product name
Rp-8-bromo-Cyclic AMPS (sodium salt)
Purity
≥98%
Packaging
500μg
Price
$175
Updated
2024/03/01
Cayman Chemical
Product number
21584
Product name
Rp-8-bromo-Cyclic AMPS (sodium salt)
Purity
≥98%
Packaging
1mg
Price
$263
Updated
2024/03/01
Cayman Chemical
Product number
21584
Product name
Rp-8-bromo-Cyclic AMPS (sodium salt)
Purity
≥98%
Packaging
5mg
Price
$963
Updated
2024/03/01
Biorbyt Ltd
Product number
orb573125
Product name
Rp-8-bromo-Cyclic AMPS
Purity
>98%
Packaging
10mg
Price
$1504.5
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573125
Product name
Rp-8-bromo-Cyclic AMPS
Purity
>98%
Packaging
20mg
Price
$2468.4
Updated
2021/12/16
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Rp-8-bromo-Cyclic AMPS (sodium salt) Chemical Properties,Usage,Production

Description

Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP.1,2 It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II from bovine heart.2

References

1. Dostmann, W.R., Taylor, S.S., Genieser, H.G., et al. Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates J. Biol. Chem. 265(18),10484-10491(1990).
2. Gjertsen, B.T., Mellgran, G., Otten, A., et al. Novel (Rp)-cAMPS analogs as tools for inhibition of cAMP-kinase in cell culture. Basal cAMP-kinase activity modulates interleukin-1β action J. Biol. Chem. 270(35),20599-20607(1995).

Rp-8-bromo-Cyclic AMPS (sodium salt) Preparation Products And Raw materials

Raw materials

Preparation Products

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Rp-8-bromo-Cyclic AMPS (sodium salt) Suppliers

China 11 United States 2 Global 13
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

925456-59-3, Rp-8-bromo-Cyclic AMPS (sodium salt)Related Search:


  • Rp-8-bromo-Cyclic AMPS (sodium salt)
  • Rp-8-bromo-Cyclic AMPS
  • 5'-cyclic monophosphorothioate
  • 8-Bromoadenosine 3'
  • RP-8-BR-CAMPS;8-BROMOADENOSINE 3';5'-CYCLIC MONOPHOSPHOROTHIOATE; RP-ISOMER;RP-8-BROMO-CAMPS;925456-59-3
  • Rp-8-bromo-cAMPS
  • Rp-isomer
  • 8-bromo-adenosinecyclic3',5'-[hydrogen[P(R)]-phosphorothioate],monosodiumsalt
  • 925456-59-3