LDN-192960 (hydrochloride)
- Product Name
- LDN-192960 (hydrochloride)
- CAS No.
- 2309172-48-1
- Chemical Name
- LDN-192960 (hydrochloride)
- Synonyms
- LDN-192960 (hydrochloride);LDN192960 hydrochloride,LDN 192960 hydrochloride;3-[(2,7-Dimethoxyacridin-9-yl)thio]-1-propanamine Dihydrochloride
- CBNumber
- CB04666529
- Molecular Formula
- C18H21ClN2O2S
- Formula Weight
- 364.89
- MOL File
- 2309172-48-1.mol
LDN-192960 (hydrochloride) Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:20.07(Max Conc. mg/mL);50.01(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);24.92(Max Conc. mM) - form
- A crystalline solid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 19089
- Product name
- LDN-192960 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $97
- Updated
- 2024/03/01
- Product number
- 19089
- Product name
- LDN-192960 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $184
- Updated
- 2024/03/01
- Product number
- 19089
- Product name
- LDN-192960 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $410
- Updated
- 2024/03/01
- Product number
- 19089
- Product name
- LDN-192960 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $768
- Updated
- 2024/03/01
- Product number
- CS-0102845
- Product name
- LDN-192960(hydrochloride)
- Purity
- ≥98.0%
- Packaging
- 10mg
- Price
- $550
- Updated
- 2021/12/16
LDN-192960 (hydrochloride) Chemical Properties,Usage,Production
Uses
LDN-192960 hydrochloride is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively[1].
IC 50
DYRK1; DYRK2
References
[1] Cuny GD, et al. Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3491-4. PMID:20836251
[2] Gregory D Cuny, et al. Structure-activity Relationship Study of Acridine Analogs as Haspin and DYRK2 Kinase Inhibitors. Bioorg Med Chem Lett DOI:10.2174/0929867324666170414155520
LDN-192960 (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
LDN-192960 (hydrochloride) Suppliers
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