ChemicalBook > CAS DataBase List > 2,6-Dichlorobenzylamine

2,6-Dichlorobenzylamine

Product Name
2,6-Dichlorobenzylamine
CAS No.
6575-27-5
Chemical Name
2,6-Dichlorobenzylamine
Synonyms
RARECHEM AL BW 0148;TIMTEC-BB SBB003780;2,6-Dichlorobenzylam;SALOR-INT L480827-1EA;2,6-DICHLOROBENZYLAMINE;2,6-Dichlorobenzylamine>2,6-Dichlorobenzylamine,98%;2,6-Dichlorobenzylamine ,99%;2,6-Dichlorobenzylamine, 97+%;(2,6-Dichlorophenyl)methylamine
CBNumber
CB0474065
Molecular Formula
C7H7Cl2N
Formula Weight
176.04
MOL File
6575-27-5.mol
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2,6-Dichlorobenzylamine Property

Melting point:
40°C
Boiling point:
108°C/ 8mm
Density 
1.320±0.06 g/cm3(Predicted)
refractive index 
1.557-1.559
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
7.98±0.10(Predicted)
form 
Liquid
color 
Clear colorless to yellow
Sensitive 
Air Sensitive
CAS DataBase Reference
6575-27-5(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
45-36/37/39-26
RIDADR 
UN2735
HazardClass 
8
PackingGroup 
III
HS Code 
29214990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L480827
Product name
2,6-DICHLOROBENZYLAMINE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$113
Updated
2025/07/31
Sigma-Aldrich
Product number
L480827
Product name
2,6-DICHLOROBENZYLAMINE
Purity
Aldrich
Packaging
500mg
Price
$110
Updated
2024/03/01
TCI Chemical
Product number
D4521
Product name
2,6-Dichlorobenzylamine
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$235
Updated
2025/07/31
TCI Chemical
Product number
D4521
Product name
2,6-Dichlorobenzylamine
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$815
Updated
2025/07/31
TRC
Product number
D437840
Product name
(2,6-Dichlorophenyl)methanamine
Packaging
2.5g
Price
$90
Updated
2021/12/16
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2,6-Dichlorobenzylamine Chemical Properties,Usage,Production

Chemical Properties

Clear pale yellow liquid

Uses

(2,6-Dichlorophenyl)methanamine was one of the reactants used in making a library of highly selective and potent G protein-coupled receptor kinase 2 inhibitors.

Synthesis

25185-95-9

6575-27-5

The general procedure for the synthesis of 2,6-dichlorobenzaldehyde oxime as raw material for 2,6-dichlorobenzylamine was as follows: 2,6-dichlorobenzaldehyde oxime (0.121 g, 1 mmol) was mixed and milled with nano Fe3O4 (0.046 g, 0.2 mmol, particle size about 70 nm) in a porcelain mortar. Subsequently, ZrCl4 (0.233 g, 1 mmol) was added and the mixture continued to be ground at room temperature. The mortar was heated in an oil bath until the temperature of the reaction mixture reached 75-80 °C. After batchwise addition of NaBH3CN (0.314 g, 5 mmol), the reaction mixture was continued to be ground at 75-80 °C for 15 min. After the reaction was completed, H2O (5 mL) was added and stirred for 5 min. The mixture was extracted with EtOAc (2 x 5 mL), the organic phases were combined and dried with anhydrous Na2SO4. Evaporation of the solvent gave a pure 2,6-dichlorobenzylamine liquid in 93% yield (0.1 g, see Table 2, entry 1).

References

[1] Journal of the Iranian Chemical Society, 2015, vol. 12, # 5, p. 873 - 878
[2] Journal of Medicinal Chemistry, 1984, vol. 27, # 9, p. 1111 - 1118

2,6-Dichlorobenzylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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2,6-Dichlorobenzylamine Suppliers

UkrOrgSynthesis Ltd.
Tel
--
Fax
--
Email
y.barysheva@ukrorgsynth.com
Country
Ukraine
ProdList
6230
Advantage
38
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View Lastest Price from 2,6-Dichlorobenzylamine manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
2,6-Dichlorobenzylamine 6575-27-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
2,6-Dichlorobenzylamine 6575-27-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-30

6575-27-5, 2,6-DichlorobenzylamineRelated Search:


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  • Anilines, Aromatic Amines and Nitro Compounds