ChemicalBook > CAS DataBase List > K-604 dihydrochloride

K-604 dihydrochloride

Product Name
K-604 dihydrochloride
CAS No.
217094-32-1
Chemical Name
K-604 dihydrochloride
Synonyms
K-604 2HCl;K-604 (K604);K-604 >=98% (HPLC);K-604 dihydrochloride;2-(4-(2-((1H-Benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide dihydrochloride;K604,K604 dihydrochloride,acyl-CoA:cholesterol acyltransferase,K-604,inhibit,K 604,Inhibitor,Diacylglycerol acyltransferase,Diglyceride acyltransferase,mono- acylglycerol acyltransferase,Acyltransferase,K 604 dihydrochloride
CBNumber
CB04797074
Molecular Formula
C23H31ClN6OS3
Formula Weight
539.17
MOL File
217094-32-1.mol
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K-604 dihydrochloride Property

storage temp. 
2-8°C
solubility 
DMSO: 62.5 mg/mL (108.57 mM)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1837
Product name
K-604
Purity
≥98% (HPLC)
Packaging
5mg
Price
$128
Updated
2024/03/01
Sigma-Aldrich
Product number
SML1837
Product name
K-604
Purity
≥98% (HPLC)
Packaging
25mg
Price
$313.8
Updated
2024/03/01
ChemScene
Product number
CS-0018788
Product name
K-604dihydrochloride
Purity
>99.0%
Packaging
10mg
Price
$390
Updated
2021/12/16
ChemScene
Product number
CS-0018788
Product name
K-604dihydrochloride
Purity
>99.0%
Packaging
5mg
Price
$230
Updated
2021/12/16
DC Chemicals
Product number
DC21196
Product name
K-604
Purity
>98%
Packaging
100mg
Price
$700
Updated
2021/12/16
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K-604 dihydrochloride Chemical Properties,Usage,Production

Biological Activity

K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with IC50 of 0.45±0.06 μM.

in vivo

Using F1B hamsters, an animal model susceptible to diet-induced hyperlipidemia and atherosclerosis, the effects of K-604 dihydrochloride on aortic lesion areas and plasma cholesterol levels are assessed.

target

ACAT-1

< span> 0.45 μM (IC 50 )

ACAT-2

102.85 μM (IC 50 )

K-604 dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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K-604 dihydrochloride Suppliers

China 23 United States 4 Global 27
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
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55
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2989
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9730
Advantage
58
Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658 18135795563
Fax
QQ:2885349392
Email
2885349392@qq.com
Country
China
ProdList
9997
Advantage
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DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9414
Advantage
58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
0519-85788828 13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
3574
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
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Shanghai Luofa Biochemical Technology Co., Ltd.
Tel
021-51111890 15317326293
Email
sales@molnova.com
Country
China
ProdList
4196
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Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44843
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Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840
Email
psaitong@jm-bio.com
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China
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Wuhan Augda Biotechnology Co., Ltd
Tel
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Fax
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Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
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product02@bidepharm.com
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China
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Kaifeng Mingren Pharmaceutical Co.,LTD
Tel
0371-65741762
Fax
QQ：2860768577
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sales@hasunny.com
Country
China
ProdList
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TargetMol Chemicals Inc.
Tel
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marketing@tsbiochem.com
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China
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Suzhou Zhixin Biotechnology Co., Ltd.
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sales@szzxbio.com
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China
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Shanghai Yiyan Biotechnology Co. , Ltd.
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China
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Anhui Xingzhou Pharmaceutical Technology Co. , Ltd.
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Shanghai Jieshikai Biotechnology Co. , Ltd.
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021-57520305 13795461237
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zhuruyan@jskchem.com
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China
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RD International Technology Co., Limited
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18024082417
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market@ubiochem.com
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China
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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info@zzsrm.com
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CHINA
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Guangzhou Weijia Technology Co., Ltd.
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WHIGA22@126.COM
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CHINA
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Wuxi Laifusi Biological Experimental Equipment Co., Ltd.
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217094-32-1, K-604 dihydrochlorideRelated Search:


  • K-604 dihydrochloride
  • K-604 (K604)
  • K-604 >=98% (HPLC)
  • K-604 2HCl
  • 2-(4-(2-((1H-Benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide dihydrochloride
  • K604,K604 dihydrochloride,acyl-CoA:cholesterol acyltransferase,K-604,inhibit,K 604,Inhibitor,Diacylglycerol acyltransferase,Diglyceride acyltransferase,mono- acylglycerol acyltransferase,Acyltransferase,K 604 dihydrochloride
  • 217094-32-1