K-604 dihydrochloride

Product Name: K-604 dihydrochloride
CAS No.: 217094-32-1
Chemical Name: K-604 dihydrochloride
Synonyms: K-604 2HCl;K-604 (K604);K-604 >=98% (HPLC);K-604 dihydrochloride;2-(4-(2-((1H-Benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide dihydrochloride;K604,K604 dihydrochloride,acyl-CoA:cholesterol acyltransferase,K-604,inhibit,K 604,Inhibitor,Diacylglycerol acyltransferase,Diglyceride acyltransferase,mono- acylglycerol acyltransferase,Acyltransferase,K 604 dihydrochloride
CBNumber: CB04797074
Molecular Formula: C23H31ClN6OS3
Formula Weight: 539.17
MOL File: 217094-32-1.mol

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K-604 dihydrochloride Property

storage temp.: 2-8°C
solubility: DMSO: 62.5 mg/mL (108.57 mM)
form: Solid
color: white to beige

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1837
Product name: K-604
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $128
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1837
Product name: K-604
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $313.8
Updated: 2024/03/01

ChemScene

Product number: CS-0018788
Product name: K-604dihydrochloride
Purity: >99.0%
Packaging: 10mg
Price: $390
Updated: 2021/12/16

ChemScene

Product number: CS-0018788
Product name: K-604dihydrochloride
Purity: >99.0%
Packaging: 5mg
Price: $230
Updated: 2021/12/16

DC Chemicals

Product number: DC21196
Product name: K-604
Purity: >98%
Packaging: 100mg
Price: $700
Updated: 2021/12/16

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K-604 dihydrochloride Chemical Properties,Usage,Production

Biological Activity

K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with IC50 of 0.45±0.06 μM.

in vivo

Using F1B hamsters, an animal model susceptible to diet-induced hyperlipidemia and atherosclerosis, the effects of K-604 dihydrochloride on aortic lesion areas and plasma cholesterol levels are assessed.

target

ACAT-1

< span> 0.45 μM (IC ₅₀ )

ACAT-2

102.85 μM (IC ₅₀ )

K-604 dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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K-604 dihydrochloride Suppliers

China 24 United States 5 Global 29

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
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Country: China
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Fan De(Beijing) Biotechnology Co., Ltd.

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Country: China
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TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
Country: United States
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Henan Weituxi Chemical Technology Co., Ltd.

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Country: China
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DC Chemicals

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Country: China
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Changzhou Chenhong Biotechnology Co., Ltd.

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Guangzhou Younan Technology Co., Ltd

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Shanghai Luofa Biochemical Technology Co., Ltd.

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217094-32-1, K-604 dihydrochlorideRelated Search:

K-604 dihydrochloride

K-604 (K604)

K-604 >=98% (HPLC)

K-604 2HCl

2-(4-(2-((1H-Benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide dihydrochloride

K604,K604 dihydrochloride,acyl-CoA:cholesterol acyltransferase,K-604,inhibit,K 604,Inhibitor,Diacylglycerol acyltransferase,Diglyceride acyltransferase,mono- acylglycerol acyltransferase,Acyltransferase,K 604 dihydrochloride

217094-32-1