ChemicalBook > CAS DataBase List > 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
- Product Name
- 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
- CAS No.
- 570407-42-0
- Chemical Name
- 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
- Synonyms
- Avatrapa impurity 10;Avatrombopag Impurity 47;Avatrombopag Impurity 13;Avatroposide impurities5;Avatroposide impurities19;2-Thiazolamine, 4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-;5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine4-(4-chlorothiophen-2-yl)-;4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine;4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-y1)thiazol-2-amine;4-(4-Chloro-thiophen-2-yl)-5-(4-cyclohexyl-piperazin-1-yl)-thiazol-2-ylamine
- CBNumber
- CB04800390
- Molecular Formula
- C17H23ClN4S2
- Formula Weight
- 382.97
- MOL File
- 570407-42-0.mol
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4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine Property
- Boiling point:
- 560.0±50.0 °C(Predicted)
- Density
- 1.345±0.06 g/cm3(Predicted)
- pka
- 7.58±0.70(Predicted)
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4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine Chemical Properties,Usage,Production
Uses
4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine is a valuable organic compound that could be used as an intermediate to synthesize thrombopoietin
Synthesis
4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine is synthesize from the reacton of 4- (4-Chloro-2-thienyl) -5-bromo-2-thiazolylamine with cyclohexylpiperazine. The reaction mixture was extracted with water and EtOAc. The combined organic phases were washed with distilled water and brine and dried to afford 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine.
4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine manufacturers
ShenZhen H&D Pharmaceutical Technology Co., LTD
- Product
- Avatrombopag Impurity 7 570407-42-0
- Price
- US $0.00/mg
- Min. Order
- 10mg
- Purity
- 0.98
- Supply Ability
- 10g
- Release date
- 2024-04-02
Zison Pharmaceutical (Shandong) Co., Ltd.
- Product
- 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine 570407-42-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98% by HPLC
- Supply Ability
- 20kg/month
- Release date
- 2023-01-05
Jinan Ande Pharmaceutical Co.,Ltd.
- Product
- 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine 570407-42-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100
- Release date
- 2021-12-20
570407-42-0, 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amineRelated Search:
Unii-4U07F515lg
Eltrombopag
Ibopamine Hydrochloride
Lusutrombopag
Avatrombopag
Avatrombopag maleate
4-(4-Chloro-2-thienyl)-2-thiazolamine
5-bromo-4-(4-chlorothiophen-2-yl)thiazol-2-amine
1-Cyclohexylpiperazine