ChemicalBook > CAS DataBase List > 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine

4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine

Product Name
4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
CAS No.
570407-42-0
Chemical Name
4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
Synonyms
Avatrapa impurity 10;Avatrombopag Impurity 47;Avatrombopag Impurity 13;Avatroposide impurities5;Avatroposide impurities19;2-Thiazolamine, 4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-;5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine4-(4-chlorothiophen-2-yl)-;4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine;4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-y1)thiazol-2-amine;4-(4-Chloro-thiophen-2-yl)-5-(4-cyclohexyl-piperazin-1-yl)-thiazol-2-ylamine
CBNumber
CB04800390
Molecular Formula
C17H23ClN4S2
Formula Weight
382.97
MOL File
570407-42-0.mol
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4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine Property

Boiling point:
560.0±50.0 °C(Predicted)
Density 
1.345±0.06 g/cm3(Predicted)
pka
7.58±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine Chemical Properties,Usage,Production

Uses

4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine is a valuable organic compound that could be used as an intermediate to synthesize thrombopoietin

Synthesis

4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine is synthesize from the reacton of 4- (4-Chloro-2-thienyl) -5-bromo-2-thiazolylamine with cyclohexylpiperazine. The reaction mixture was extracted with water and EtOAc. The combined organic phases were washed with distilled water and brine and dried to afford 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine.
4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine

4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine manufacturers

Zison Pharmaceutical (Shandong) Co., Ltd.
Product
4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine 570407-42-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98% by HPLC
Supply Ability
20kg/month
Release date
2023-01-05
ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Avatrombopag Impurity 7 570407-42-0
Price
US $0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-02
Jinan Ande Pharmaceutical Co.,Ltd.
Product
4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine 570407-42-0
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100
Release date
2021-12-20

570407-42-0, 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amineRelated Search:


  • 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
  • 2-Thiazolamine, 4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-
  • Avatrombopag Impurity 13
  • 5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine4-(4-chlorothiophen-2-yl)-
  • Avatrombopag Impurity 47
  • Avatroposide impurities19
  • 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-y1)thiazol-2-amine
  • 4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine (Avatrombopag Impurity)
  • Avatroposide impurities5
  • Avatrapa impurity 10
  • 4-(4-Chloro-thiophen-2-yl)-5-(4-cyclohexyl-piperazin-1-yl)-thiazol-2-ylamine
  • 570407-42-0
  • C17H23ClN4S2
  • Intermediate
  • Intermediate