1-Cyclohexylpiperazine
- Product Name
- 1-Cyclohexylpiperazine
- CAS No.
- 17766-28-8
- Chemical Name
- 1-Cyclohexylpiperazine
- Synonyms
- AKOS BBS-00003612;BUTTPARK 82\06-06;TIMTEC-BB SBB003875;Avatopal impurity 47;N-Cyclohexylpiperazine;1-Cyclohexylpiperizine;1-CYCLOHEXYLPIPERAZINE;Avatrombopag Impurity 9;Piperazine, 1-cyclohexyl-;Avatroposide impurities15
- CBNumber
- CB1309032
- Molecular Formula
- C10H20N2
- Formula Weight
- 168.28
- MOL File
- 17766-28-8.mol
1-Cyclohexylpiperazine Property
- Melting point:
- 28-32 °C
- Boiling point:
- 287.25°C (rough estimate)
- Density
- 0.9725 (rough estimate)
- refractive index
- 1.6011
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Low Melting Solid
- pka
- 9.25±0.10(Predicted)
- color
- Yellow-brownish
- BRN
- 106845
- InChI
- InChI=1S/C10H20N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h10-11H,1-9H2
- InChIKey
- XPDSXKIDJNKIQY-UHFFFAOYSA-N
- SMILES
- N1(C2CCCCC2)CCNCC1
- CAS DataBase Reference
- 17766-28-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C1783
- Product name
- 1-Cyclohexylpiperazine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $42
- Updated
- 2025/07/31
- Product number
- C1783
- Product name
- 1-Cyclohexylpiperazine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $126
- Updated
- 2025/07/31
- Product number
- C988102
- Product name
- 1-Cyclohexylpiperazine
- Packaging
- 500mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 409578
- Product name
- 1-Cyclohexylpiperazine
- Packaging
- 500mg
- Price
- $319
- Updated
- 2021/12/16
- Product number
- FC56321
- Product name
- 1-Cyclohexylpiperazine
- Packaging
- 100g
- Price
- $476
- Updated
- 2021/12/16
1-Cyclohexylpiperazine Chemical Properties,Usage,Production
Chemical Properties
yellow-brownish low melting solid
Uses
1-Cyclohexylpiperazine is an σ1 and σ2 receptor ligands with diagnostic and therapeutic potentials.
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 7331, 1994 DOI: 10.1016/0040-4039(94)85306-1
Materials Uses
1-Cyclohexylpiperazine can be used to develop new luminescent materials such as [CYP]ZnBr4 (CYP = 1-cyclohexylpiperazine). It is a highly efficient blue luminescent lead-free halide material with high luminous efficiency (photoluminescence quantum yield up to 79.22%) and stability, which can be used to manufacture highly efficient blue phosphors for white light-emitting diodes (LEDs) [1].
Synthesis
1224935-95-8
17766-28-8
General procedure for the synthesis of 1-cyclohexylpiperazine from tert-butyl 4-cyclohexylpiperazine-1-carboxylate: tert-butyl 4-cyclohexylpiperazine-1-carboxylate (1.38 g, 5.15 mmol) was dissolved in a mixture of ethanol/hydrochloric acid (15 mL), and the reaction was stirred for 18 h at room temperature. After completion of the reaction, the solvent was removed by distillation under reduced pressure. To the residue, 5 mL of water was added and the aqueous phase was washed with ethyl acetate (5 mL × 3). Subsequently, the aqueous phase was adjusted to pH 7~8 with base and extracted with ethyl acetate (10 mL × 3). All organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give 0.78 g of 1-cyclohexylpiperazine (confirmed by LC-MS and TLC, yield: 90.1%).
References
[1] Wang, Yu-Yin et al. “High Emission Efficiency and Thermal Stability in Zero-Dimensional Hybrid Zinc Halide as a Blue Light Emitter.” Inorganic chemistry vol. 62,38 (2023): 15711-15718. doi:10.1021/acs.inorgchem.3c02313
1-Cyclohexylpiperazine Preparation Products And Raw materials
Raw materials
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View Lastest Price from 1-Cyclohexylpiperazine manufacturers
- Product
- 1-Cyclohexylpiperazine 17766-28-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- ＞99% by GC
- Supply Ability
- 50kg
- Release date
- 2023-01-05
- Product
- 1-Cyclohexylpiperazine 17766-28-8
- Price
- US $2900.00/Kg
- Min. Order
- 1Kg
- Purity
- 98
- Supply Ability
- 500 Kg
- Release date
- 2024-05-08
- Product
- 1-Cyclohexylpiperazine 17766-28-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100
- Release date
- 2021-12-18