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UPGL00004

Product Name
UPGL00004
CAS No.
1890169-95-5
Chemical Name
UPGL00004
Synonyms
UPGL00004;UPGL00004,UPGL-00004;2-Phenyl-N-(5-(4-((5-(2-phenylacetamido)-1,3,4-thiadiazol-2-yl)amino)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide;Benzeneacetamide, N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]-1-piperidinyl]-1,3,4-thiadiazol-2-yl]-
CBNumber
CB04800860
Molecular Formula
C25H26N8O2S2
Formula Weight
534.66
MOL File
1890169-95-5.mol
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UPGL00004 Property

Density 
1.460±0.06 g/cm3(Predicted)
pka
9.23±0.50(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0068007
Product name
UPGL00004
Purity
≥98.0%
Packaging
5mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-0068007
Product name
UPGL00004
Purity
≥98.0%
Packaging
50mg
Price
$1200
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573368
Product name
UPGL00004
Purity
>98%
Packaging
100mg
Price
$1208.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573368
Product name
UPGL00004
Purity
>98%
Packaging
250mg
Price
$2395.3
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573368
Product name
UPGL00004
Purity
>98%
Packaging
1g
Price
$4766.8
Updated
2021/12/16
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UPGL00004 Chemical Properties,Usage,Production

Biological Activity

UPGL00004 is a potent glutaminase C (GAC) inhibitor with IC50 of 29 nM, more selective for GAC than GLS2.

in vitro

Administration of UPGL00004 in combination with the anti-VEGF antibody bevacizumab effectively inhibited triple-negative breast cancer cell growth and tumor growth.

in vivo

Administration of UPGL00004 in combination with the anti-VEGF antibody bevacizumab inhibited tumor growth in a human xenograft model of breast cancer.

target

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 29 nM
TargetValue
glutaminase C
(Cell-free assay)

UPGL00004 Preparation Products And Raw materials

Raw materials

Preparation Products

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UPGL00004 Suppliers

China 34 United States 4 Global 38
Wuhan Acumen Bio-Technology Co.,ltd
Tel
027-027-16602739303 16602739303
Email
673003916@qq.com
Country
China
ProdList
2887
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4153
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2989
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9747
Advantage
58
MQ (shanghai) Pharmaceuticals Co., Ltd.
Tel
13761635123
Fax
1014988033@qq
Email
1014988033@qq.com
Country
China
ProdList
4981
Advantage
55
Heze Development Zone chuangli Chemical Co., Ltd.
Tel
+86-530-529 6766，+86-15666160102 15666160102
Fax
0530-529 6766
Email
info@chuangli-chem.com
Country
China
ProdList
875
Advantage
55
Shanghai Yu Ben Biotechnology Co., Ltd.
Tel
15502154572
Fax
-
Email
yuben012@sina.com
Country
China
ProdList
504
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10523
Advantage
58

1890169-95-5, UPGL00004Related Search:


  • UPGL00004
  • UPGL00004,UPGL-00004
  • Benzeneacetamide, N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]-1-piperidinyl]-1,3,4-thiadiazol-2-yl]-
  • 2-Phenyl-N-(5-(4-((5-(2-phenylacetamido)-1,3,4-thiadiazol-2-yl)amino)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide
  • 1890169-95-5