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UPGL00004

Product Name
UPGL00004
CAS No.
1890169-95-5
Chemical Name
UPGL00004
Synonyms
UPGL00004;UPGL00004,UPGL-00004;2-Phenyl-N-(5-(4-((5-(2-phenylacetamido)-1,3,4-thiadiazol-2-yl)amino)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide;Benzeneacetamide, N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]-1-piperidinyl]-1,3,4-thiadiazol-2-yl]-;2-Phenyl-N-(5-(4-((5-(2-phenylacetamido)-1,3,4-thiadiazol-2-yl)amino)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide , UPGL00004
CBNumber
CB04800860
Molecular Formula
C25H26N8O2S2
Formula Weight
534.66
MOL File
1890169-95-5.mol
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UPGL00004 Property

Density 
1.460±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 2mg/mL, clear
form 
Solid
pka
9.23±0.50(Predicted)
color 
Off-white to gray
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0068007
Product name
UPGL00004
Purity
≥98.0%
Packaging
5mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-0068007
Product name
UPGL00004
Purity
≥98.0%
Packaging
50mg
Price
$1200
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573368
Product name
UPGL00004
Purity
>98%
Packaging
100mg
Price
$1208.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573368
Product name
UPGL00004
Purity
>98%
Packaging
250mg
Price
$2395.3
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573368
Product name
UPGL00004
Purity
>98%
Packaging
1g
Price
$4766.8
Updated
2021/12/16
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UPGL00004 Chemical Properties,Usage,Production

Biological Activity

UPGL00004 is a potent glutaminase C (GAC) inhibitor with IC50 of 29 nM, more selective for GAC than GLS2.

in vitro

Administration of UPGL00004 in combination with the anti-VEGF antibody bevacizumab effectively inhibited triple-negative breast cancer cell growth and tumor growth.

in vivo

Administration of UPGL00004 in combination with the anti-VEGF antibody bevacizumab inhibited tumor growth in a human xenograft model of breast cancer.

target

< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> 29 nM
TargetValue
glutaminase C
(Cell-free assay)

UPGL00004 Preparation Products And Raw materials

Raw materials

Preparation Products

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UPGL00004 Suppliers

China 37 United States 4 Global 41
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58

1890169-95-5, UPGL00004Related Search:


  • UPGL00004
  • UPGL00004,UPGL-00004
  • Benzeneacetamide, N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]-1-piperidinyl]-1,3,4-thiadiazol-2-yl]-
  • 2-Phenyl-N-(5-(4-((5-(2-phenylacetamido)-1,3,4-thiadiazol-2-yl)amino)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide
  • 2-Phenyl-N-(5-(4-((5-(2-phenylacetamido)-1,3,4-thiadiazol-2-yl)amino)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide , UPGL00004
  • 1890169-95-5