ChemicalBook > CAS DataBase List > RS 25344 hydrochloride

RS 25344 hydrochloride

Product Name
RS 25344 hydrochloride
CAS No.
152815-28-6
Chemical Name
RS 25344 hydrochloride
Synonyms
RS 25344 HCl;RS-25344 hydrochloride, 10 mM in DMSO;1-(3-Nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione hydrochloride;memory,cognition,human,RS25344 hydrochloride,antineoplastic,RS-25344,Inhibitor,anti-inflammatory,RS 25344,inhibit,Phosphodiesterase (PDE),RS25344,RS 25344 hydrochloride,lymphocytes,cAMP
CBNumber
CB04806453
Molecular Formula
C19H14ClN5O4
Formula Weight
411.8
MOL File
152815-28-6.mol
More
Less

RS 25344 hydrochloride Property

storage temp. 
Desiccate at RT
solubility 
<20.59mg/ml in Water; <41.18mg/ml in DMSO
form 
Solid
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
R701013
Product name
RS25344Hydrochloride
Packaging
50mg
Price
$715
Updated
2021/12/16
ApexBio Technology
Product number
B7361
Product name
1-(3-nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione hydrochloride
Packaging
10mg
Price
$253
Updated
2021/12/16
ApexBio Technology
Product number
B7361
Product name
1-(3-nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione hydrochloride
Packaging
50mg
Price
$1073
Updated
2021/12/16
CSNpharm
Product number
CSN23075
Product name
RS25344HCl
Packaging
10mg
Price
$135
Updated
2021/12/16
CSNpharm
Product number
CSN23075
Product name
RS25344HCl
Packaging
25mg
Price
$301
Updated
2021/12/16
More
Less

RS 25344 hydrochloride Chemical Properties,Usage,Production

Uses

RS 25344 Hydrochloride is a phosphdiesterase (PDE 4) inhibitor.

in vivo

RS-25344 hydrochloride (5 mg/kg; i.p.; twice daily for 72 h) results in significant increases in stomach weights in wild type C57BL/6 mice[3].
RS-25344 hydrochloride (1 mg/kg; i.p.; 30 min prior to food bolus) increases gastric retention in mice[3].

IC 50

PDE Ⅳ: 0.28 nM (IC50); PDE Ⅰ: >100 μM (IC50); PDE Ⅱ: 160 μM (IC50); PDE Ⅲ: 330 μM (IC50)

RS 25344 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

RS 25344 hydrochloride Suppliers

China 25 United Kingdom 1 United States 2 USA 1 Global 29
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77

152815-28-6, RS 25344 hydrochlorideRelated Search:


  • RS 25344 HCl
  • 1-(3-Nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione hydrochloride
  • memory,cognition,human,RS25344 hydrochloride,antineoplastic,RS-25344,Inhibitor,anti-inflammatory,RS 25344,inhibit,Phosphodiesterase (PDE),RS25344,RS 25344 hydrochloride,lymphocytes,cAMP
  • RS-25344 hydrochloride, 10 mM in DMSO
  • 152815-28-6