ChemicalBook > CAS DataBase List > MC180295
MC180295
- Product Name
- MC180295
- CAS No.
- 2237942-08-2
- Chemical Name
- MC180295
- Synonyms
- MC180295;(rel)-MC180295;MC-180295;MC 180295;MC180295, 10 mM in DMSO;MC180295 ((REL)-MC180295);MC180295,MC 180295,Cyclin dependent kinase,MC-180295,CDK,inhibit,Inhibitor;Methanone, [4-amino-2-[(1R,2R,4S)-bicyclo[2.2.1]hept-2-ylamino]-5-thiazolyl](2-nitrophenyl)-, rel-
- CBNumber
- CB04923806
- Molecular Formula
- C17H18N4O3S
- Formula Weight
- 358.41
- MOL File
- 2237942-08-2.mol
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MC180295 Property
- Boiling point:
- 623.8±65.0 °C(Predicted)
- Density
- 1.462±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 100 mg/mL (279.01 mM)
- form
- Solid
- pka
- 2.40±0.10(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0081067
- Product name
- MC180295
- Purity
- 98.47%
- Packaging
- 5mg
- Price
- $650
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0081067
- Product name
- MC180295
- Purity
- 98.47%
- Packaging
- 10mg
- Price
- $950
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb573229
- Product name
- MC180295
- Purity
- >98%
- Packaging
- 100mg
- Price
- $1802
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0081067
- Product name
- MC180295
- Purity
- 98.47%
- Packaging
- 50mg
- Price
- $2850
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb573229
- Product name
- MC180295
- Purity
- >98%
- Packaging
- 250mg
- Price
- $3136.5
- Updated
- 2021/12/16
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MC180295 Chemical Properties,Usage,Production
Uses
MC180295 can be useful in combination therapy of BET proteolysis targeting chimeric mol. with CDK9 inhibitor against human multiple myeloma cells.
Biological Activity
MC180295 ((rel)-MC180295) is a novel potent and selective CDK9 inhibitor with IC50 of 5 nM, at least 22-fold selective for CDK9 over other CDKs.
in vivo
MC180295 has antitumor and immunoallergic activity.
target
| Target | Value |
| CDK9-Cyclin T1 (Cell-free assay) | 5 nM |
| CDK4-Cyclin D (Cell-free assay) | 112 nM |
| CDK1-Cyclin B (Cell-free assay) | 138 nM |
| CDK5-P35 < br/> (Cell-free assay) | 159 nM |
| CDK5-P25 (Cell-free assay) | 186 nM |
MC180295 Preparation Products And Raw materials
Raw materials
Preparation Products
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MC180295 Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6391
- Advantage
- 58
- Tel
- +1-+1(833)-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 52924
- Advantage
- 58
- Tel
- support@targetmol.com
- Country
- United States
- ProdList
- 38631
- Advantage
- 58