S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O
- Product Name
- S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O
- CAS No.
- 5653-80-5
- Chemical Name
- S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O
- Synonyms
- d-methadone;6s-methadone;S-(+)-Methadone;l-(+)-methadone;dextromethadone;4-diphenyl-6-(dimethylamino)-(s)-3-heptanon;d-6-(dimethylamino)-4,4-diphenyl-3-heptanone;(s)-6-(dimethylamino)-4,4-diphenyl-3-heptanone;(6S)-6-(diMethylaMino)-4,4-diphenylheptan-3-one;3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (6S)-
- CBNumber
- CB0498241
- Molecular Formula
- C21H27NO
- Formula Weight
- 309.45
- MOL File
- 5653-80-5.mol
S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Property
- Melting point:
- 100.5°C
- Boiling point:
- 449.71°C (rough estimate)
- Density
- 1.0350 (rough estimate)
- refractive index
- 1.5614 (estimate)
- solubility
- H2O: soluble
- form
- solid
- pka
- 9.05±0.50(Predicted)
- color
- white
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-42/43
- Safety Statements
- 22-26-36/37/39-45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- MJ6000000
- Toxicity
- LD50 oral in mouse: 252mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P285In case of inadequate ventilation wear respiratory protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Chemical Properties,Usage,Production
Uses
Dextromethadone-D3 is an impurity of Dextromethadone (CAS #: 5653-80-5). Dextromethadone is used in therapy for treating or preventing depression or other mood diseases.
Definition
ChEBI: Dextromethadone is a 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (S)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder. It has a role as a NMDA receptor antagonist and an opioid analgesic. It is an enantiomer of a levomethadone.