PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL&
- Product Name
- PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL&
- CAS No.
- 72556-74-2
- Chemical Name
- PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL&
- Synonyms
- dichlorophosphinate;Colifos Tetrahydrate;Merival Tetrahydrate;Isocolin Tetrahydrate;Mebophos Tetrahydrate;Ipercolin Tetrahydrate;Pancholin Tetrahydrate;Biocalcose Tetrahydrate;Phoscholin Tetrahydrate;Epafosforil Tetrahydrate
- CBNumber
- CB0499026
- Molecular Formula
- ClN(CH3)3CH2CH2OPO3Ca4H2O
- Formula Weight
- 329.73
- MOL File
- 72556-74-2.mol
PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL& Property
- storage temp.
- -20°C
- solubility
- Water (Slightly)
- Water Solubility
- Soluble in water
- form
- powder to crystal
- color
- White to Almost white
- biological source
- synthetic (organic)
- Merck
- 14,7362
- BRN
- 4835230
- Stability:
- Stable, but light sensitive and may also be heat sensitive. Store at -20℃.
- InChI
- InChI=1S/Ca.2Cl2HO2P.4H2O/c;2*1-5(2,3)4;;;;/h;2*(H,3,4);4*1H2/q+2;;;;;;/p-2
- InChIKey
- WOCFGZLMOWLHFB-UHFFFAOYSA-L
- SMILES
- [Ca+2].ClP(Cl)([O-])=O.ClP(Cl)([O-])=O.[H]O[H].[H]O[H].[H]O[H].[H]O[H]
- CAS DataBase Reference
- 72556-74-2
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P0378
- Product name
- Phosphocholine chloride calcium salt tetrahydrate
- Purity
- Sigma Grade
- Packaging
- 10mg
- Price
- $30.5
- Updated
- 2025/07/31
- Product number
- P0378
- Product name
- Phosphocholine chloride calcium salt tetrahydrate
- Purity
- Sigma Grade
- Packaging
- 5g
- Price
- $77.62
- Updated
- 2025/07/31
- Product number
- P0274
- Product name
- Phosphocholine Chloride Calcium Salt Tetrahydrate
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $121
- Updated
- 2025/07/31
- Product number
- P0274
- Product name
- Phosphocholine Chloride Calcium Salt Tetrahydrate
- Purity
- >98.0%(T)
- Packaging
- 250g
- Price
- $721
- Updated
- 2025/07/31
- Product number
- P0378
- Product name
- Phosphocholine chloride calcium salt tetrahydrate
- Purity
- Sigma Grade
- Packaging
- 25g
- Price
- $291
- Updated
- 2025/07/31
PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL& Chemical Properties,Usage,Production
Description
Phosphocholine chloride calcium salt tetrahydrate is a phospholipid and also an essential component of cell membranes. It is involved in many cellular processes such as cell growth, differentiation, membrane transport and signal transduction, and can be used to study the effects of phospholipids on cell growth and differentiation. It can also be used as an intermediate raw material for synthetic enzymatic hydrolysis of lignin (EHL)-grafted phosphobetaine (EHLPB).
Chemical Properties
white powder
Uses
Phosphocholine Chloride is a specific promoter of heparin and serum β-lipoprotein interaction. Phosphocholine Chloride protected the membranes of platelets, erythrocytes, and lysosomes against the labilizing action of various known membrane labilizers.
Synthesis
67-48-1
72556-74-2
1. 1032 g of orthophosphoric acid was added to a 2L four-neck flask and heated to 160-165°C. 2. 2. a mixed clarified solution consisting of 1032 g of orthophosphoric acid and 852 g of choline chloride was added slowly and dropwise, maintaining the temperature at 160°C for 2 hours, during which time it was ensured that no water vapor was generated and about 520 g of distillate was collected. 3. Transfer the reaction solution to a 50L glass reactor, cool to 30°C, add 15kg of pure water and stir until the solution becomes colorless and transparent, at which time the pH should be 1-2. 4. Add 520g of calcium chloride and stir at room temperature until completely dissolved. 5. 5. Slowly add 900g of calcium carbonate, observe a large number of foam generation and the liquid becomes white milky, stirring at room temperature for 30 minutes. 6. Add 540g of calcium hydroxide, continue to stir at room temperature for 30 minutes, adjust and maintain the pH to 8.0, the liquid is still white milky. 7. Add 2kg of purified water, make sure the pH is stabilized at 8.0, then centrifuge and filter, and wash the filter cake with purified water. 8. Calcium hydroxide was added to the filter cake, the pH was adjusted to 9-13, centrifugation was performed again, and 2.3 kg of calcium phosphate solid was obtained after drying. 9. The filtrate was filtered through a 0.2 μm PP microfiltration membrane to obtain 21 kg of colorless transparent liquid. 10. The liquid was concentrated to 4L using an experimental ultrafiltration membrane at 1.5MPa and 20-30°C. The liquid was then filtered through a 0.5μm PP microfiltration membrane. 11. Add 1.5L of 95% ethanol, stir for 30 minutes and then crystallize at 0-5°C for 3 hours and vacuum filter. 12. Wash the filter cake with 2150 ml of 75% ethanol/pure water (1:1 v/v) and stir the mixture at room temperature. 13. Add 10L of 95% ethanol, the solution gradually changed from turbid to milky white, left to drain. 14. Dry the wet product in vacuum at 60 ℃ for 3 hours to get 1052g N,N,N-trimethyl-2-(phosphonooxy)ethanaminium chloride calcium salt tetrahydrate dry product. 15. Product analysis: Chlorine content 10.7%, phosphorus content 9.5%, calcium content 12.4%, titer content 98.8%. Infrared spectrum conforms to the reference standard.
IC 50
Human Endogenous Metabolite; Microbial Metabolite
References
[1] Patent: CN103936785, 2016, B. Location in patent: Paragraph 0027-0032
PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL& Preparation Products And Raw materials
Raw materials
Preparation Products
PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL& Suppliers
- Tel
- 18639096640
- hnxxflst@163.com
- Country
- China
- ProdList
- 44
- Advantage
- 58
- Tel
- 2537653158 16621191650
- Fax
- QQ 2537653158
- 2537653158@qq.com
- Country
- China
- ProdList
- 7273
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44802
- Advantage
- 61
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11032
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- 0731-85526065 13308475853
- ivy@hnhbsj.com
- Country
- China
- ProdList
- 7247
- Advantage
- 62
View Lastest Price from PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL& manufacturers
- Product
- Phosphocholine Chloride CalciuM Salt Tetrahydrate 72556-74-2
- Price
- US $0.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20Ton
- Release date
- 2024-10-28