BENZYL 3-PYRROLINE-1-CARBOXYLATE

Product Name: BENZYL 3-PYRROLINE-1-CARBOXYLATE
CAS No.: 31970-04-4
Chemical Name: BENZYL 3-PYRROLINE-1-CARBOXYLATE
Synonyms: N-Cbz-pyrroline;N-Cbz-3-pyrroline;N-Cbz-2,5-dihydropyrrole;2,5-Dihydropyrrole-1-Cbz;N-Carbobenzoxy-3-pyrroline;N-Cbz 2,5-dihydro-1H-pyrrole;1-Cbz-2,5-dihydro-1H-pyrrole;Benzyl 3-pyrroline-1-formate;N-Carbobenzoxy-3-pyrroline >3-pyrroline-1-benzylcarboxylate
CBNumber: CB0499440
Molecular Formula: C12H13NO2
Formula Weight: 203.24
MOL File: 31970-04-4.mol

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BENZYL 3-PYRROLINE-1-CARBOXYLATE Property

Boiling point:: 133-137 °C0.6 mm Hg(lit.)
Density: 1.132 g/mL at 25 °C(lit.)
refractive index: n20/D 1.544(lit.)
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: -1.51±0.20(Predicted)
form: Liquid
color: Colorless to pale yellow
InChI: InChI=1S/C12H13NO2/c14-12(13-8-4-5-9-13)15-10-11-6-2-1-3-7-11/h1-7H,8-10H2
InChIKey: XSKKIFJNZPNVGO-UHFFFAOYSA-N
SMILES: N1(C(OCC2=CC=CC=C2)=O)CC=CC1
CAS DataBase Reference: 31970-04-4

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C2872
Product name: N-Carbobenzoxy-3-pyrroline
Purity: >97.0%(GC)
Packaging: 1g
Price: $52
Updated: 2025/07/31

TCI Chemical

Product number: C2872
Product name: N-Carbobenzoxy-3-pyrroline
Purity: >97.0%(GC)
Packaging: 5g
Price: $247
Updated: 2025/07/31

TRC

Product number: B288745
Product name: Benzyl 3-pyrroline-1-carboxylate
Packaging: 2.5g
Price: $165
Updated: 2021/12/16

Chem-Impex

Product number: 43870
Product name: N-Carbobenzoxy-3-pyrroline,≥97%(GC)
Purity: ≥97%(GC)
Packaging: 1G
Price: $47.38
Updated: 2021/12/16

AK Scientific

Product number: J97935
Product name: Benzyl 3-pyrroline-1-carboxylate
Packaging: 10g
Price: $66
Updated: 2021/12/16

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BENZYL 3-PYRROLINE-1-CARBOXYLATE Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Uses

Benzyl 3-Pyrroline-1-carboxylate is an heterocyclic building block used in the synthesis of pharmaceutical products including inhibitors. It is used in synthesis of novel series of pyrrolotriazine, acting as a pan-Aurora kinase inhibitors.

Synthesis

3-Pyrroline was added to a round-bottomed flask, 10% aqueous sodium carbonate was added and stirred to dissolve, then dioxane was added, and a 10% dioxane solution of benzyl chloroformate was slowly added dropwise into the reaction solution under an ice bath, and after the dropwise addition was completed the reaction was carried out in an ice bath for 2 hours, and then at room temperature for 8 hours, and the reaction was diluted with the addition of water, and extracted with ether 4 times, the aqueous layer was placed in an ice bath, the pH was adjusted with concentrated hydrochloric acid until the Congo red paper showed blue, placed in a refrigerator overnight, the white precipitate was extracted with ethyl acetate, the combined organic liquids were washed with water, the organic layer was dried with anhydrous magnesium sulfate, and pumped dry to obtain the product benzyl 2,5-dihydropyrrolidine-1-carboxylate.

BENZYL 3-PYRROLINE-1-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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BENZYL 3-PYRROLINE-1-CARBOXYLATE Suppliers

Americas 1 China 152 Europe 1 India 4 Japan 1 Switzerland 1 United Kingdom 3 United States 20 Global 183

Cool Pharm, Ltd

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J & K SCIENTIFIC LTD.

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Alfa Aesar

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Energy Chemical

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Suzhou Highfine Biotech Co., Ltd

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Jia Xing Isenchem Co.,Ltd

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View Lastest Price from BENZYL 3-PYRROLINE-1-CARBOXYLATE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Benzyl 2,5-dihydro-1H-pyrrole-1-carboxylate 31970-04-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-08

Shaanxi Dideu Medichem Co. Ltd

Product: BENZYL 3-PYRROLINE-1-CARBOXYLATE 90 31970-04-4
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2020-04-27

Shaanxi Dideu Medichem Co. Ltd

Product: Benzyl 3-pyrroline-1-carboxylate 31970-04-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 100 tons
Release date: 2019-12-30

31970-04-4, BENZYL 3-PYRROLINE-1-CARBOXYLATERelated Search:

Benzyl formate

benzyl 2,5-dihydropyrrole-1-carboxylate

2,5-Dihydro-1H-pyrrole, N-CBZ protected

2,5-dihydropyrrole-1-carboxylic acid (phenylmethyl) ester

N-Cbz 2,5-dihydro-1H-pyrrole

benzyl 2,5-dihydro-1H-pyrrole-1-carboxylate

N-(Benzyloxycarbonyl)3-pyrroline

2,5-Dihydropyrrole-1-Cbz

N-Cbz-2,5-dihydropyrrole

3-pyrroline-1-benzylcarboxylate

N-Cbz-3-pyrroline

BENZYL 3-PYRROLINE-1-CARBOXYLATE 90

N-Carbobenzoxy-3-pyrroline

benzyl 2H-pyrrole-1(5H)-carboxylate

2,5-Dihydropyrrole-1-carboxylic acid benzyl ester

1-Cbz-2,5-dihydro-1H-pyrrole

Benzyl 3-pyrroline-1-carboxylate

Benzyl 3-pyrroline-1-formate

N-Carbobenzoxy-3-pyrroline &gt

1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-, phenylmethyl ester

N-Cbz-pyrroline

31970-04-4

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