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RIMEXOLONE (100 MG)

Product Name
RIMEXOLONE (100 MG)
CAS No.
49697-38-3
Chemical Name
RIMEXOLONE (100 MG)
Synonyms
Vexol;Rimexel;Org-6216;Rimexolone;Rimexolone D6;Rimexolone D5;(11β,16α,17β)-;RIMEXOLONE (100 MG);Rimexolone (1604600);Benzoyl Peroxide Impurity 9
CBNumber
CB0500540
Molecular Formula
C24H34O3
Formula Weight
370.53
MOL File
49697-38-3.mol
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RIMEXOLONE (100 MG) Property

Melting point:
258-268 ºC
alpha 
D +100° (c = 0.92 in pyridine)
Boiling point:
507.0±50.0 °C(Predicted)
Density 
1.12
pka
14.42±0.70(Predicted)
InChIKey
QTTRZHGPGKRAFB-OOKHYKNYSA-N
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Safety

HS Code 
2937290000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1604600
Product name
Rimexolone
Packaging
100mg
Price
$432
Updated
2024/03/01
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RIMEXOLONE (100 MG) Chemical Properties,Usage,Production

Description

Rimexolone, an ophthalmic corticosteroid, was launched in 1995 in the U.S.A. for the treatment of postoperative inflammation following ocular surgery and anterior uveitis. Rimexolone has high corticoid receptor affinity and is a potent local antiinflammatory agent with minimal systemic effects and virtually no atrophogenic action in many animal models studied, unique among a wide range of topical steroids. Rapid onset, long duration of action plus a superior safety profile are characteristics of rimexolone. It was also approved in Europe for the treatment of rheumatoid arthritis and is currently in clinical trials for tendinitis and osteoarthritis.

Originator

Akzo (Netherlands)

Uses

Anti-inflammatory (local).

Definition

ChEBI: Rimexolone is a 20-oxo steroid.

brand name

Vexol (Alcon).

General Description

Rimexolone, 11β-hydroxy-16α,17α-dimethyl-17-(1-oxopropyl)androsta-1,4-diene-3-one,like medrysone and fluorometholone, lacks the C21 OHgroup. In addition, rimexolone has an additional methylgroup in the 17 -position, a site where an OH group is typicallyfound. Rimexolone is available as a suspension forophthalmic use.

RIMEXOLONE (100 MG) Preparation Products And Raw materials

Raw materials

Preparation Products

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RIMEXOLONE (100 MG) Suppliers

Canada 1 China 46 Europe 1 France 1 Germany 1 India 2 The Netherlands 1 United Kingdom 1 United States 7 Global 61
Chemsky (shanghai) International Co.,Ltd
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View Lastest Price from RIMEXOLONE (100 MG) manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
RIMEXOLONE (100 MG) 49697-38-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-04-01
Career Henan Chemical Co
Product
RIMEXOLONE 49697-38-3
Price
US $1000.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2018-07-23

49697-38-3, RIMEXOLONE (100 MG)Related Search:

RIMEXOLONE (100 MG)

  • (11β,16α,17β)-
  • (17S)-11β-Hydroxy-16α,17α-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one
  • 11β-Hydroxy-16α,17α-dimethyl-17β-propionylandrosta-1,4-dien-3-one
  • Org-6216
  • (11b,16a,17b)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one
  • RIMEXOLONE (100 MG)
  • Rimexolone
  • (11β, 16α, 17β)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androstra-1,4-dien-3-one
  • Androsta-1,4-dien-3-one, 11-hydroxy-16,17-dimethyl-17-(1-oxopropyl)-, (11β,16α,17β)-
  • Rimexolone D5
  • Rimexolone D6
  • Rimexolone (1604600)
  • Rimexel
  • Vexol
  • Methylprednisolone Impurity 31 (Rimexolone)
  • Benzoyl Peroxide Impurity 9
  • 49697-38-3
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids