10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
- Product Name
- 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
- CAS No.
- 29331-92-8
- Chemical Name
- 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
- Synonyms
- GP 47779;BIA 2-005;GP 47779-d3;BIA 2-005-d3;Licarbazepine;Hydroxycarbamazepine;Licarbazepine Racemate;10,11-Dihydro-10-hydroxy;LICARBAZEPINE SEE 16178912;Oxcarbazepine Hydroxy Impurity
- CBNumber
- CB0500702
- Molecular Formula
- C15H14N2O2
- Formula Weight
- 254.28
- MOL File
- 29331-92-8.mol
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Property
- Melting point:
- 186-189°C
- Boiling point:
- 431.3±55.0 °C(Predicted)
- Density
- 1.336
- Flash point:
- 2℃
- storage temp.
- -20°C
- solubility
- Soluble to 100 mM in DMSO and to 50 mM in ethanol
- pka
- 13.75±0.20(Predicted)
- BRN
- 1540211
- InChIKey
- BMPDWHIDQYTSHX-UHFFFAOYSA-N
- CAS DataBase Reference
- 29331-92-8
Safety
- Hazard Codes
- N,Xn,F
- Risk Statements
- 51/53-36-20/21/22-11
- Safety Statements
- 61-36/37-26-16
- RIDADR
- UN 3077 9 / PGIII
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- PHR3294
- Product name
- Licarbazepine
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 50MG
- Price
- $344
- Updated
- 2024/03/01
- Product number
- D-091
- Product name
- 10,11-Dihydro-10-Hydroxycarbamazepine solution
- Purity
- 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $140
- Updated
- 2024/03/01
- Product number
- 61347
- Product name
- 10,11-Dihydro-10-hydroxycarbamazepine
- Purity
- analytical standard
- Packaging
- 25mg
- Price
- $1000
- Updated
- 2024/03/01
- Product number
- 18467
- Product name
- 10,11-dihydro-10-hydroxy Carbamazepine
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $50
- Updated
- 2024/03/01
- Product number
- 18467
- Product name
- 10,11-dihydro-10-hydroxy Carbamazepine
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $94
- Updated
- 2024/03/01
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
A metabolite of Oxcarbazepine
Uses
A labelled metabolite of Oxcarbazepine
Uses
10,11-dihydro-10-hydroxy Carbamazepinee is the active metabolite of oxcarbazepine . Oxcarbazepine is rapidly and almost completely converted to 10,11-dihydro-10-hydroxycarbamazepine, which then demonstrates anticonvulsant efficacy by modulating several ion channels and receptors. ?10,11-dihydro-10-hydroxy Carbamazepine is reported to inhibit both voltage-gated Na+ and Ca2+ channels, to potentiate voltage-gated K+ channels, to antagonize adenosine A1 receptors, to increase dopaminergic transmission, and to inhibit glutamate release.
Definition
ChEBI: A dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel b ocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine.
storage
Store at RT
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Preparation Products And Raw materials
Raw materials
Preparation Products
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Suppliers
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- Product
- 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE 29331-92-8
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-30