10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

Product Name: 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
CAS No.: 29331-92-8
Chemical Name: 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
Synonyms: GP 47779;BIA 2-005;GP 47779-d3;BIA 2-005-d3;Licarbazepine;Hydroxycarbamazepine;Licarbazepine Racemate;10,11-Dihydro-10-hydroxy;LICARBAZEPINE SEE 16178912;Oxcarbazepine Hydroxy Impurity
CBNumber: CB0500702
Molecular Formula: C15H14N2O2
Formula Weight: 254.28
MOL File: 29331-92-8.mol

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10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Property

Melting point:: 186-189°C
Boiling point:: 431.3±55.0 °C(Predicted)
Density: 1.336
Flash point:: 2℃
storage temp.: -20°C
solubility: Soluble to 100 mM in DMSO and to 50 mM in ethanol
form: Solid
pka: 13.75±0.20(Predicted)
color: White to off-white
BRN: 1540211
InChIKey: BMPDWHIDQYTSHX-UHFFFAOYSA-N
CAS DataBase Reference: 29331-92-8

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Safety

Hazard Codes: N,Xn,F
Risk Statements: 51/53-36-20/21/22-11
Safety Statements: 61-36/37-26-16
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3294
Product name: Licarbazepine
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 50MG
Price: $344
Updated: 2024/03/01

Sigma-Aldrich

Product number: D-091
Product name: 10,11-Dihydro-10-Hydroxycarbamazepine solution
Purity: 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $140
Updated: 2024/03/01

Sigma-Aldrich

Product number: 61347
Product name: 10,11-Dihydro-10-hydroxycarbamazepine
Purity: analytical standard
Packaging: 25mg
Price: $1000
Updated: 2024/03/01

Cayman Chemical

Product number: 18467
Product name: 10,11-dihydro-10-hydroxy Carbamazepine
Purity: ≥98%
Packaging: 5mg
Price: $50
Updated: 2024/03/01

Cayman Chemical

Product number: 18467
Product name: 10,11-dihydro-10-hydroxy Carbamazepine
Purity: ≥98%
Packaging: 10mg
Price: $94
Updated: 2024/03/01

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10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A metabolite of Oxcarbazepine

Uses

A labelled metabolite of Oxcarbazepine

Uses

10,11-dihydro-10-hydroxy Carbamazepinee is the active metabolite of oxcarbazepine . Oxcarbazepine is rapidly and almost completely converted to 10,11-dihydro-10-hydroxycarbamazepine, which then demonstrates anticonvulsant efficacy by modulating several ion channels and receptors. ?10,11-dihydro-10-hydroxy Carbamazepine is reported to inhibit both voltage-gated Na+ and Ca2+ channels, to potentiate voltage-gated K+ channels, to antagonize adenosine A1 receptors, to increase dopaminergic transmission, and to inhibit glutamate release.

Definition

ChEBI: A dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel b ocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine.

storage

Store at RT

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Preparation Products And Raw materials

Raw materials

Preparation Products

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10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Suppliers

Canada 1 China 116 India 8 United Kingdom 3 United States 16 Global 144

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View Lastest Price from 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE manufacturers

Career Henan Chemical Co

Product: 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE 29331-92-8
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-01-30

29331-92-8, 10,11-DIHYDRO-10-HYDROXYCARBAZEPINERelated Search:

Oxcarbazepine Hydroxy Impurity

5-Carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepine-10-ol

6-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide

10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide

10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxaMide

10,11-Dihydro-10-hydroxy

(±)-10-Hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxaMide

5H-Dibenz[b,f]azepine-5-carboxaMide,10,11-dihydro-10-hydroxy-

10,11-Dihydro-10-Hydroxycarbamazepine solution

5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide

10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide

10-Hydroxy-10,11-dihydrocarbamezepine

BIA 2-005

GP 47779

Licarbazepine

10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide-d3

10,11-Dihydro-10-hydroxycarbazepine-d3

10-Hydroxy-10,11-dihydrocarbamezepine-d3

BIA 2-005-d3

GP 47779-d3

LICARBAZEPINE SEE 16178912

Hydroxycarbamazepine

10-Hydroxy-10,11-dihydrocarbamazepi

Dihydrohydroxy carbamazepine-D4

10,11-hydroxy-10,11 Dihydrocarbamezer

Licarbazepine Racemate

10,11-Dihydro-10-hydroxy-Carbamazepin

(±)-10-Hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carbox...

10,11-Dihydro-10-hydroxy carbamazepine D7

10,11-dihydro-10-Hydroxy CarbamazepineQ: What is 10,11-dihydro-10-Hydroxy Carbamazepine Q: What is the CAS Number of 10,11-dihydro-10-Hydroxy Carbamazepine Q: What is the storage condition of 10,11-dihydro-10-Hydroxy Carbamazepine Q: What are the applications of 10,11-dihydro-10-Hydroxy Carbamazepine

1H-Benzimidazole,2-(6-methoxyethyl)-

(±) -10,11-Dihydro-10-hydroxy-5H-dibenzo[b,f]azepine-5-carboxamide

10,11-Dihydro-10-hydroxycarbamazepine in methanol

Licarbazepine (10,11-Dihydro-10-hydroxycarbamazepine), Active oxcarbazepine metabolite

29331-92-8

84006-10-4

C15H11D3N2O2

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

Isotope Labeled Compounds