4-BROMO-5-FLUORO-1,2-PHENYLENEDIAMINE 98
- Product Name
- 4-BROMO-5-FLUORO-1,2-PHENYLENEDIAMINE 98
- CAS No.
- 153505-37-4
- Chemical Name
- 4-BROMO-5-FLUORO-1,2-PHENYLENEDIAMINE 98
- Synonyms
- 4-Bromo-5-fluoro-2-amino-aniline;4-Bromo-5-fluoro-o-phenylenediamine;4-Bromo-5-fluoro-1,2-benzenediamine;1,2-BenzenediaMine, 4-broMo-5-fluoro-;4-Bromo-5-fluorobenzene-1,2-diamine97%;4-Bromo-5-fluorobenzene-1,2-diamine 97%;4-BROMO-5-FLUORO-1,2-PHENYLENEDIAMINE 98;4-Bromo-5-fluoro-1,2-phenylenediamine 98%;4-Bromo-5-fluorophenylene-1,2-diamine, 4-Bromo-1,2-diamino-5-fluorobenzene;4-Bromo-5-fluorophenylene-1,2-diamine, 1-Bromo-4,5-diamino-2-fluorobenzene
- CBNumber
- CB0501042
- Molecular Formula
- C6H6BrFN2
- Formula Weight
- 205.03
- MOL File
- 153505-37-4.mol
4-BROMO-5-FLUORO-1,2-PHENYLENEDIAMINE 98 Property
- Boiling point:
- 297.0±35.0 °C(Predicted)
- Density
- 1.792±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 3.15±0.10(Predicted)
- form
- powder
- color
- Brown
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant
- HS Code
- 2921511990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B686518
- Product name
- 4-Bromo-5-fluorobenzene-1,2-diamine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- J91220
- Product name
- 4-Bromo-5-fluorobenzene-1,2-diamine
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
- Product number
- 3630-B-X2
- Product name
- 4-Bromo-5-fluoro-1,2-phenylenediamine
- Purity
- 98%
- Packaging
- 1g
- Price
- $77
- Updated
- 2021/12/16
- Product number
- PC9574
- Product name
- 4-Bromo-5-fluorobenzene-1,2-diamine
- Purity
- 97%
- Packaging
- 1g
- Price
- $48
- Updated
- 2021/12/16
- Product number
- J91220
- Product name
- 4-Bromo-5-fluorobenzene-1,2-diamine
- Packaging
- 5g
- Price
- $210
- Updated
- 2021/12/16
4-BROMO-5-FLUORO-1,2-PHENYLENEDIAMINE 98 Chemical Properties,Usage,Production
Synthesis
153505-36-3
153505-37-4
General procedure for the synthesis of 4-bromo-5-fluoro-2-nitroaniline from 4-bromo-5-fluoro-2-nitroaniline: to a solution of 4-bromo-5-fluoro-2-nitroaniline (1.0 g, 4.3 mmol) in THF (9.0 mL) was added EtOH (9.0 mL) and H2O (3 mL), followed by the addition of iron powder (1.2 g, 21.3 mmol) and ammonium chloride (0.34 g, 6.4 mmol). The reaction mixture was heated to reflux at 95 °C for 4 hours. After completion of the reaction, the mixture was cooled to room temperature, diluted with EtOH and filtered through a diatomaceous earth pad until the filtrate was colorless. The filtrate was concentrated under reduced pressure, the residue was dissolved in EtOAc, washed sequentially with H2O and brine, the organic phase was dried with anhydrous Na2SO4, filtered and concentrated. Hexane was added to the concentrate and the precipitated solid was collected by filtration to afford the title compound 4-bromo-5-fluorobenzene-1,2-diamine (710 mg, 3.5 mmol, 81% yield).
References
[1] Patent: EP2566477, 2015, B1. Location in patent: Paragraph 0172; 0173
[2] Patent: WO2012/83170, 2012, A1. Location in patent: Page/Page column 155
[3] Patent: WO2013/26914, 2013, A1. Location in patent: Page/Page column 134
[4] Patent: US2007/259936, 2007, A1. Location in patent: Page/Page column 175
[5] Patent: US2010/222345, 2010, A1. Location in patent: Page/Page column 69
4-BROMO-5-FLUORO-1,2-PHENYLENEDIAMINE 98 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-BROMO-5-FLUORO-1,2-PHENYLENEDIAMINE 98 manufacturers
- Product
- 4-BROMO-5-FLUORO-1,2-PHENYLENEDIAMINE 98 153505-37-4
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-07
- Product
- 4-BROMO-5-FLUORO-1,2-PHENYLENEDIAMINE 98 153505-37-4
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 10000MT
- Release date
- 2023-08-17
- Product
- diamine 153505-37-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.2%
- Supply Ability
- 100 tons
- Release date
- 2022-02-08