BETAZOLE HYDROCHLORIDE

Product Name: BETAZOLE HYDROCHLORIDE
CAS No.: 138-92-1
Chemical Name: BETAZOLE HYDROCHLORIDE
Synonyms: histalog;Histimin;gastramine;Histalog (TN);betazolehydrochloride;betazoledihydrochloride;2-(3-Pyrazolyl)ethylamin;ametazoledihydrochloride;Betazole hydrochloride (JAN);BETAZOLE HYDROCHLORIDE (200 MG)
CBNumber: CB0501633
Molecular Formula: C5H11Cl2N3
Formula Weight: 184.06694
MOL File: 138-92-1.mol

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BETAZOLE HYDROCHLORIDE Property

Melting point:: 224-226°
storage temp.: Store at -20°C
solubility: DMSO: 37 mg/mL (201.01 mM);Ethanol: 18 mg/mL (97.79 mM)
Water Solubility: Water: 37 mg/mL (201.01 mM)

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Safety

HS Code: 2933199090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B276680
Product name: BetazoleDihydrochloride
Packaging: 2.5mg
Price: $160
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP126823
Product name: Betazole dihydrochloride
Packaging: 250mg
Price: $172.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP126823
Product name: Betazole dihydrochloride
Packaging: 2g
Price: $867
Updated: 2021/12/16

Apolloscientific

Product number: OR471576
Product name: 2-(3-Pyrazolyl)ethanaminedihydrochloride
Packaging: 5g
Price: $1827
Updated: 2021/12/16

Matrix Scientific

Product number: 077451
Product name: [2-(1H-Pyrazol-3-yl)ethyl]amine dihydrochloride
Packaging: 5g
Price: $2310
Updated: 2021/12/16

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BETAZOLE HYDROCHLORIDE Chemical Properties,Usage,Production

Originator

Histalog,Lilly,US,1953

Uses

Betazole Hydrochloride is a histamine H2 receptor agonist that is used as a gastric stimulant for the investigation of gastric secretion activity.

Definition

ChEBI: The dihydrochloride salt of betazole.

Manufacturing Process

A solution of 55 grams (1.1 mol) of hydrazine hydrate in 100 ml of methanol was cooled in a water bath and stirred while a solution of 48 grams (0.50 mol) of pure γ-pyrone in 100 ml of methanol was added over a period of about 15 minutes. After the addition was complete, the solution was allowed to stand at room temperature for about 1 hour, and was placed in a 1 liter hydrogenation bomb. 25 ml of liquid ammonia were added cautiously with stirring, followed by about 15 cc of Raney nickel catalyst. The bomb was charged with hydrogen to 1,800 pounds pressure, heated to 90°C and agitated. The quantity of hydrogen required to convert the hydrazone into the desired aminoethylpyrazole was taken up in about 3 hours. The bomb was cooled and opened, and the contents filtered. The filtrate was evaporated under reduced pressure to remove the methanol and the residual liquid was distilled under reduced pressure, whereby there were obtained 44.5 grams (81% yield) of 3-β-aminoethylpyrazole boiling at 118°-123°C at a pressure of 0.5 mm of Hg.

brand name

Histalog (Lilly).

Therapeutic Function

Diagnostic aid (gastric secretion)

BETAZOLE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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BETAZOLE HYDROCHLORIDE Suppliers

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138-92-1, BETAZOLE HYDROCHLORIDERelated Search:

Norvoncomycin hydrochloride Phenylhydrazine hydrochloride Terazosin hydrochloride Metacycline hydrochloride Xylazine Hydrochloride SPECTINOMYCIN DIHYDROCHLORIDE Hydralazine hydrochloride 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINE DIHYDROCHLORIDE 4,5,6,7-TETRAHYDRO-2-METHYL-2H-PYRAZOLO[4,3-C]PYRIDINE DIHYDROCHLORIDE BETAZOLE HYDROCHLORIDE 3-(4-chlorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride 2-phenyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine dihydrochloride RARECHEM AN KD 0464 RARECHEM AN KB 2415 RARECHEM AN KB 1606 1-(4-CHLOROPHENYL)-5-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-PYRAZOL-5-YL)-3-(4-FLUOROBENZYL)-2,4(1H,3H)-PYRIMIDINEDIONE 11-(2,5-DICHLOROPHENYL)-2,3-DIMETHOXY-5,11,12,12A-TETRAHYDROPYRAZOLO[3',4':4,5]PYRIDO[2,1-A]ISOQUINOLIN-8(6H)-ONE RARECHEM AN KC 0456

2-(1H-pyrazol-5-yl)ethan-1-amine dihydrochloride

betazolehydrochloride

gastramine

histalog

BETAZOLE HYDROCHLORIDE (200 MG)

Histimin

[2-(1H-Pyrazol-3-yl)ethyl]amine dihydrochloride

2-(1H-pyrazol-3-yl)ethanamine dihydrochloride

2-(3-Pyrazolyl)ethylamin

2-(2H-pyrazol-3-yl)ethanamine dihydrochloride

2-(2H-pyrazol-3-yl)ethylamine dihydrochloride

ametazoledihydrochloride

betazoledihydrochloride

1h-pyrazole-3-ethanamine,dihydrochloride

3-(2-aminoethyl)-pyrazoldihydrochloride

3-(2-aminoethyl)pyrazole,dihydrochloride

3,5-beta-pyrazoleethylaminedihydrochloride

3-beta-aminoethylpyrazoledihydrochloride

Betazole hydrochloride (JAN)

Histalog (TN)

Pyrazole, 3-(2-aminoethyl)-, dihydrochloride

2-(3-Pyrazolyl)ethanamine Dihydrochloride

BETAZOLE HYDROCHLORIDE USP/EP/BP

Betazole Hydrochloride (1070006)

secretion,bile,Betazole,gastric,acid,Histamine Receptor,inhibit,Betazole dihydrochloride,duct,secretory,histalog,Ametazole,capacity,pressure,Inhibitor

138-92-1

Amine, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals