Diethylstilbestrol

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Diethylstilbestrol

Product Name: Diethylstilbestrol
CAS No.: 6898-97-1
Chemical Name: Diethylstilbestrol
Synonyms: DES;Diethylstilbestrol;Diethylstillbestrol;3,4-Bis(4-hydroxypheny;Diethylstilbestrol >(E,Z)-Diethylstilbestrol;Diethylstilbestrol-(E,Z);Atovaquone CAS NO.6898-97-1;Diethylstilbestrol USP/EP/BP;4,4'-Hex-3-ene-3,4-diyldiphenol
CBNumber: CB0503501
Molecular Formula: C18H20O2
Formula Weight: 268.35
MOL File: 6898-97-1.mol

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Diethylstilbestrol Property

Melting point:: 170-172 °C(lit.)
Boiling point:: 407.1±25.0 °C(Predicted)
Density: 1.107±0.06 g/cm3(Predicted)
solubility: soluble in Methanol
form: powder to crystal
pka: 9.27±0.15(Predicted)
color: White to Almost white
Merck: 14,3129
InChIKey: RGLYKWWBQGJZGM-ISLYRVAYSA-N
CAS DataBase Reference: 6898-97-1

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Safety

Hazard Codes: T,N
Risk Statements: 45-61-36/37/38-51/53
Safety Statements: 53-36/37/39-45-60-61
RIDADR: UN 3077 9/PG 3
WGK Germany: 3
RTECS: WJ5600000
HazardClass: 9
PackingGroup: III
HS Code: 29072990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H350May cause cancer

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 218944
Product name: Diethylstilbestrol, mixture of cis and trans
Purity: 97%
Packaging: 5g
Price: $113
Updated: 2023/06/20

TCI Chemical

Product number: D0526
Product name: Diethylstilbestrol
Purity: >98.0%(GC)
Packaging: 1g
Price: $48
Updated: 2024/03/01

TCI Chemical

Product number: D0526
Product name: Diethylstilbestrol
Purity: >98.0%(GC)
Packaging: 5g
Price: $119
Updated: 2024/03/01

Usbiological

Product number: 446129
Product name: Des-
Packaging: 2.5mg
Price: $460
Updated: 2021/12/16

Usbiological

Product number: 446134
Product name: Des-
Packaging: 10mg
Price: $460
Updated: 2021/12/16

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Diethylstilbestrol Chemical Properties,Usage,Production

Description

Diethylstilbestrol is a derivative of stilbene, and it differs from sin-estrol by the presence of a double bond with trans-configuration of the two phenyl groups. In terms of estrogenic activity, this drug surpasses both estrone and hexestrol.

Chemical Properties

White solid

Uses

Diethylstilbestrol was used as internal standard for the analysis of drug residues in urine of rats and calves by on-line HPLC with ultraviolet and continuous-flow fast atom bombardmentmass spectrometry detectors.

Definition

ChEBI: Diethylstilbestrol is an olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. It has a role as an antineoplastic agent, a carcinogenic agent, a xenoestrogen, an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor, an antifungal agent, an endocrine disruptor, an EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor, an autophagy inducer and a calcium channel blocker. It is a polyphenol and an olefinic compound.

General Description

Mechanisms of the isomerization processes of molecular and anionic diethylstilbestrol (DES) has been reported. Estrogen activity of cis- and trans-diethylstilbestrol has been evaluated. Diethylstilbestrol is a carcinogenic synthetic estrogen.

Synthesis

Diethylstilbestrol, trans-|á,|?-diethyl-4,4-stilbendiol (28.1.34), is proposed to be synthesized in various ways. According to one of them, desoxyansoine is alkylated by ethyl iodide in the presence of sodium ethoxide, and the resulting ketone (28.1.30) is reacted in a Grignard reaction with ethylmagnesium bromide, which forms the carbinol (28.1.31). Dehydration of this compound by distillation in the presence of p-toluenesulfonic acid gives dimethyl ether of stilbestrol (28.1.32), methyl groups of which are removed by heating it at high temperatures with potassium hydroxide, thus forming diethylstilbestrol (28.1.33).

Diethylstilbestrol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Diethylstilbestrol manufacturers

Wuhan Haorong Biotechnology Co.,Ltd

Product: Diethylstilbestrol 6898-97-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500
Release date: 2023-07-31

Shaanxi Dideu Medichem Co. Ltd

Product: Diethylstilbestrol 6898-97-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-26

WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD

Product: Diethylstilbestrol 6898-97-1
Price: US $0.00/KG
Min. Order: 100g
Purity: 98%+
Supply Ability: 100kg
Release date: 2020-09-08

6898-97-1, DiethylstilbestrolRelated Search:

4-(4-CHLORO-BENZYLOXY)-PHENYLAMINE VINYL PROPIONATE N-Vinyl-2-pyrrolidone p-(2-Methoxyethyl) phenol Vinyl resin Leuprorelin Acetate Vinyl ester resin Leuprorelin DIETHYLSTILBESTROL DIPHOSPHATE,diethylstilbestrol bisphosphate HEXESTROL Histrelin Diethylstilbestrol diphosphate tetra sodium salt DIETHYLSTILBESTROL GLUCURONIDE,Diethylstilbestrol b-D-Glucuronide,Diethylstilbestrol -D-Glucuronide Diethylstilbestrol propionate,DIETHYLSTILBESTROL DIPROPIONATE TRANS-DIETHYLSTILBESTROL,Diethylstilbestrol,Diethylstilbestrol (DES),DIETHYLSTILBESTROL,USP (D-LEU7)-HISTRELIN (DES-GLY10,D-HIS2,D-TRP6,PRO-NHET9)-LHRH DIETHYLSTILBESTROL MONOMETHYL ETHER,DIETHYLSTILBESTROL METHYL ETHER

DIETHYLSTILBESTROL 97% MIXTURE OF CIS&

diethylstilbestrol, mixture of cis and trans

Diethylstilbestrol,mixture of cis and trans

DIETHYLSTILBESTROL, 99%, MIXTURE OF CIS AND TRANS

3,4-Bis(4-hydroxyphenyl)-3-hexene

4,4'-(1,2-Diethylvinylene)bisphenol

4,4'-(3-Hexene-3,4-diyl)bisphenol

3,4-Bis(4-hydroxypheny

4-[1-ethyl-2-(4-hydroxyphenyl)but-1-enyl]phenol

4-[4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol

4,4'-Hex-3-ene-3,4-diyldiphenol

DES

Diethylstilbestrol

Diethylstillbestrol

Diethylstilbestrol, mixture of cis and trans 97%

Diethylstilbestrol &gt

Phenol, 4,4'-(1,2-diethyl-1,2-ethenediyl)bis-

(E,Z)-Diethylstilbestrol

(E,Z)-Diethylstilbestrol Solution in Methanol, 100μg/mL

Diethylstilbestrol USP/EP/BP

a,a’-Diethyl-4,4’-stilbenediol D4

Atovaquone CAS NO.6898-97-1

Diethylstilbestrol-(E,Z)

6898-97-1

Acyclic

Alkenes

Bioactive Small Molecules

Building Blocks

Cell Biology

Chemical Synthesis

D-DIF

Organic Building Blocks

Stilbenes