Tianeptine

ChemicalBook > CAS DataBase List > Tianeptine

Product Name: Tianeptine
CAS No.: 72797-41-2
Chemical Name: Tianeptine
Synonyms: Tianeptin;TPI-1062;TIANEPTINE;JNJ-39823277;Einecs 276-851-9;Tianeptine in acetonitrile;72797-41-2;7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid;7-((3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanoic acid;(1)-7-((3-Chloro-6,11-dihydro-6-methyldibenzo(C,F)(1,2)thiazepin-11-yl)amino)heptanoic acid S,S-dioxide
CBNumber: CB0504881
Molecular Formula: C21H25ClN2O4S
Formula Weight: 436.95
MOL File: 72797-41-2.mol

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Tianeptine Property

Melting point:: 129-131?C
Boiling point:: 609.2±65.0 °C(Predicted)
Density: 1.38±0.1 g/cm3(Predicted)
vapor pressure: 0.001Pa at 25℃
storage temp.: Refrigerator, Under Inert Atmosphere
pka: 4.75±0.10(Predicted)
form: solid
InChIKey: JICJBGPOMZQUBB-UHFFFAOYSA-N
SMILES: C(O)(=O)CCCCCCNC1C2=CC=C(Cl)C=C2S(=O)(=O)N(C)C2=CC=CC=C21
LogP: 2.162 at 25℃ and pH6

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

H362May cause harm to breast-fed children

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: T436800
Product name: Tianeptine
Packaging: 5mg
Price: $85
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FT28263
Product name: Tianeptine
Packaging: 1g
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FT28263
Product name: Tianeptine
Packaging: 5mg
Price: $124.9
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FT28263
Product name: Tianeptine
Packaging: 2g
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FT28263
Product name: Tianeptine
Packaging: 10mg
Price: $227.2
Updated: 2021/12/16

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Tianeptine Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. It is used mainly in the treatment of major depressive disorder and may also be used to treat anxiety, asthma, and irritable bowel syndrome. It has been found to act as an atypical agonist of the μ-opioid receptor with clinically negligible effects on the δ- and κ-opioid receptors. Tianeptine prevents chronic stress-induced morphological changes in the hippocampus and amygdala and blocks the effects of acute stress on synaptic plasticity in the hippocampus and PFC.

Definition

ChEBI: Tianeptine is a racemate comprising of equimolar amounts of (R)- and (S)-tianeptine. It is an atypical antidepressant used in Europe to treat patients who respond poorly to selective serotonin reuptake inhibitors (SSRIs). It has a role as a mu-opioid receptor agonist, a second generation antipsychotic and an anxiolytic drug. It contains a (R)-tianeptine and a (S)-tianeptine.

brand name

Stablon, Tatinol, and Coaxil among others

Mechanism of action

Current research suggests that tianeptine produces its antidepressant effects through the modulation of glutamate receptor activity (for example, AMPA receptors and NMDA receptors) and affect the release of brain-derived neurotrophic factor (BDNF), which impacts neural plasticity.

Tianeptine Preparation Products And Raw materials

Raw materials

Preparation Products

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Tianeptine Suppliers

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View Lastest Price from Tianeptine manufacturers

Hebei Mojin Biotechnology Co.,Ltd

Product: TIANEPTINE 72797-41-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-08-01

Hebei Kangcang new material Technology Co., LTD

Product: Tianeptine
Price: US $5.00/kg
Min. Order: 0.10000000149011612kg
Purity: 99.99%
Supply Ability: 20tons
Release date: 2024-03-14

Hebei Kangcang new material Technology Co., LTD

Product: Tianeptine /acid 72797-41-2
Price: US $2000.00-1500.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 100ton/ month
Release date: 2024-03-20

72797-41-2, TianeptineRelated Search:

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(±)-7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S-dioxide

(1)-7-((3-Chloro-6,11-dihydro-6-methyldibenzo(C,F)(1,2)thiazepin-11-yl)amino)heptanoic acid S,S-dioxide

Einecs 276-851-9

7-((3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanoic acid

7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid

Tianeptin

JNJ-39823277

TPI-1062

Tianeptine D4Q: What is Tianeptine D4 Q: What is the CAS Number of Tianeptine D4 Q: What is the storage condition of Tianeptine D4 Q: What are the applications of Tianeptine D4

TIANEPTINE

Tianeptine in acetonitrile

72797-41-2

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