ChemicalBook > CAS DataBase List > Tianeptine
Tianeptine
- Product Name
- Tianeptine
- CAS No.
- 72797-41-2
- Chemical Name
- Tianeptine
- Synonyms
- Tianeptin;TPI-1062;TIANEPTINE;JNJ-39823277;Einecs 276-851-9;72797-41-2;7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid;7-((3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanoic acid;(1)-7-((3-Chloro-6,11-dihydro-6-methyldibenzo(C,F)(1,2)thiazepin-11-yl)amino)heptanoic acid S,S-dioxide;(±)-7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S-dioxide
- CBNumber
- CB0504881
- Molecular Formula
- C21H25ClN2O4S
- Formula Weight
- 436.95
- MOL File
- 72797-41-2.mol
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Tianeptine Property
- Melting point:
- 129-131?C
- Boiling point:
- 609.2±65.0 °C(Predicted)
- Density
- 1.38±0.1 g/cm3(Predicted)
- vapor pressure
- 0.001Pa at 25℃
- storage temp.
- Refrigerator, Under Inert Atmosphere
- pka
- 4.75±0.10(Predicted)
- form
- solid
- InChIKey
- JICJBGPOMZQUBB-UHFFFAOYSA-N
- SMILES
- C(O)(=O)CCCCCCNC1C2=CC=C(Cl)C=C2S(=O)(=O)N(C)C2=CC=CC=C21
- LogP
- 2.162 at 25℃ and pH6
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Safety
- WGK Germany
- 3
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P263Avoid contact during pregnancy/while nursing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P281Use personal protective equipment as required.
P308+P313IF exposed or concerned: Get medical advice/attention.
P314Get medical advice/attention if you feel unwell.
P405Store locked up.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
TRC
- Product number
- T436800
- Product name
- Tianeptine
- Packaging
- 5mg
- Price
- $85
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FT28263
- Product name
- Tianeptine
- Packaging
- 1g
- Price
- $120
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FT28263
- Product name
- Tianeptine
- Packaging
- 5mg
- Price
- $124.9
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FT28263
- Product name
- Tianeptine
- Packaging
- 2g
- Price
- $200
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FT28263
- Product name
- Tianeptine
- Packaging
- 10mg
- Price
- $227.2
- Updated
- 2021/12/16
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Tianeptine Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. It is used mainly in the treatment of major depressive disorder and may also be used to treat anxiety, asthma, and irritable bowel syndrome. It has been found to act as an atypical agonist of the μ-opioid receptor with clinically negligible effects on the δ- and κ-opioid receptors. Tianeptine prevents chronic stress-induced morphological changes in the hippocampus and amygdala and blocks the effects of acute stress on synaptic plasticity in the hippocampus and PFC.
Definition
ChEBI: Tianeptine is a racemate comprising of equimolar amounts of (R)- and (S)-tianeptine. It is an atypical antidepressant used in Europe to treat patients who respond poorly to selective serotonin reuptake inhibitors (SSRIs). It has a role as a mu-opioid receptor agonist, a second generation antipsychotic and an anxiolytic drug. It contains a (R)-tianeptine and a (S)-tianeptine.
brand name
Stablon, Tatinol, and Coaxil among others
Mechanism of action
Current research suggests that tianeptine produces its antidepressant effects through the modulation of glutamate receptor activity (for example, AMPA receptors and NMDA receptors) and affect the release of brain-derived neurotrophic factor (BDNF), which impacts neural plasticity.
Tianeptine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Tianeptine manufacturers
Hunan aslsen technology co.,ltd
- Product
- Tianeptine 72797-41-2
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000 tons
- Release date
- 2024-04-16
Hebei Kangcang new material Technology Co., LTD
- Product
- Tianeptine
- Price
- US $5.00/kg
- Min. Order
- 0.10000000149011612kg
- Purity
- 99.99%
- Supply Ability
- 20tons
- Release date
- 2024-03-14
Hebei Kangcang new material Technology Co., LTD
- Product
- Tianeptine /acid 72797-41-2
- Price
- US $2000.00-1500.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 100ton/ month
- Release date
- 2024-03-20
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