OPIPRAMOL
- Product Name
- OPIPRAMOL
- CAS No.
- 315-72-0
- Chemical Name
- OPIPRAMOL
- Synonyms
- G-33040;Nisidana;GR-33040;Opramidol;OPIPRAMOL;NSC 169867;Opipramol in acetonitrile;N-[3-[4-(2-hydroxyethyl)piperazino]propyl]iminostilbene;4-(3-(DIBENZ(B,F)AZEPIN-5-YL)PROPYL)-1-PIPERAZINEETHANOL;1-Piperazineethanol, 4-3-(5H-dibenzb,fazepin-5-yl)propyl-
- CBNumber
- CB6415167
- Molecular Formula
- C23H29N3O
- Formula Weight
- 363.5
- MOL File
- 315-72-0.mol
OPIPRAMOL Property
- Melting point:
- 100-1010C
- Boiling point:
- 494.88°C (rough estimate)
- Density
- 1.0920 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- -20°C Freezer
- solubility
- Acetonitrile: slightly soluble; Chloroform: slightly soluble; Methanol: slightly soluble
- pka
- pKa 8(H2O,t =25,I=0.01(NaCl)) (Uncertain)
- form
- Solid
- color
- Light yellow to yellow
- BRN
- 627076
N-Bromosuccinimide Price
- Product number
- 29471
- Product name
- Opipramol
- Packaging
- 5mg
- Price
- $39
- Updated
- 2024/03/01
- Product number
- 29471
- Product name
- Opipramol
- Packaging
- 10mg
- Price
- $70
- Updated
- 2024/03/01
- Product number
- 29471
- Product name
- Opipramol
- Packaging
- 25mg
- Price
- $152
- Updated
- 2024/03/01
- Product number
- O669600
- Product name
- Opipramol
- Packaging
- 10mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- O669600
- Product name
- Opipramol
- Packaging
- 5mg
- Price
- $105
- Updated
- 2021/12/16
OPIPRAMOL Chemical Properties,Usage,Production
Chemical Properties
Crystalline Solid
Originator
Insidon,Geigy,W. Germany,1962
Uses
Antidepressant; antipsychotic
Definition
ChEBI: 2-[4-[3-(11-benzo[b][1]benzazepinyl)propyl]-1-piperazinyl]ethanol is a dibenzoazepine.
Manufacturing Process
A solution of 5-(3-toluene-p-sulfonyloxypropyl)dibenzazepine (9.2g) and 1-(2hydroxyethyl)piperazine (8.6g) in anhydrous toluene (50 cc) is heated at boiling point under reflux for 4 hours.
After cooling, distilled water (75 cc) is added. The aqueous phase is decanted. The toluene solution is washed with distilled water (25 cc) and then extracted with N hydrohloric acid (40 cc). The hydrochloric acid solution is made alkaline to phenolphthalein with sodium hydroxide (d = 1.33).The base which separates is extracted with chloroform (50 cc). The chloroform solution is dried over anhydrous sodium sulfate and then evaporated to dryness. There are obtained 5-[3-(4-β-hydroxyethylpiperazino)propyl]dibenzazepine (7.95g), the dihydrochloride of which, crystallized from ethanol, melts at about 210°C.
Therapeutic Function
Antidepressant, Antipsychotic
OPIPRAMOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from OPIPRAMOL manufacturers
- Product
- OPIPRAMOL 315-72-0
- Price
- US $1.00/G
- Min. Order
- 1G
- Purity
- 99%
- Supply Ability
- 1KG
- Release date
- 2024-05-21