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OPIPRAMOL

Product Name
OPIPRAMOL
CAS No.
315-72-0
Chemical Name
OPIPRAMOL
Synonyms
G-33040;Nisidana;GR-33040;Opramidol;OPIPRAMOL;NSC 169867;Opipramol in acetonitrile;N-[3-[4-(2-hydroxyethyl)piperazino]propyl]iminostilbene;4-(3-(DIBENZ(B,F)AZEPIN-5-YL)PROPYL)-1-PIPERAZINEETHANOL;1-Piperazineethanol, 4-3-(5H-dibenzb,fazepin-5-yl)propyl-
CBNumber
CB6415167
Molecular Formula
C23H29N3O
Formula Weight
363.5
MOL File
315-72-0.mol
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OPIPRAMOL Property

Melting point:
100-1010C
Boiling point:
494.88°C (rough estimate)
Density 
1.0920 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
-20°C Freezer
solubility 
Acetonitrile: slightly soluble; Chloroform: slightly soluble; Methanol: slightly soluble
pka
pKa 8(H2O,t =25,I=0.01(NaCl)) (Uncertain)
form 
Solid
color 
Light yellow to yellow
BRN 
627076
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Safety

Hazard Codes 
Xn,N
Risk Statements 
22-50/53
Safety Statements 
60-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
1
RTECS 
TL8750000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29471
Product name
Opipramol
Packaging
5mg
Price
$39
Updated
2024/03/01
Cayman Chemical
Product number
29471
Product name
Opipramol
Packaging
10mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
29471
Product name
Opipramol
Packaging
25mg
Price
$152
Updated
2024/03/01
TRC
Product number
O669600
Product name
Opipramol
Packaging
10mg
Price
$155
Updated
2021/12/16
TRC
Product number
O669600
Product name
Opipramol
Packaging
5mg
Price
$105
Updated
2021/12/16
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OPIPRAMOL Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Originator

Insidon,Geigy,W. Germany,1962

Uses

Antidepressant; antipsychotic

Definition

ChEBI: 2-[4-[3-(11-benzo[b][1]benzazepinyl)propyl]-1-piperazinyl]ethanol is a dibenzoazepine.

Manufacturing Process

A solution of 5-(3-toluene-p-sulfonyloxypropyl)dibenzazepine (9.2g) and 1-(2hydroxyethyl)piperazine (8.6g) in anhydrous toluene (50 cc) is heated at boiling point under reflux for 4 hours.
After cooling, distilled water (75 cc) is added. The aqueous phase is decanted. The toluene solution is washed with distilled water (25 cc) and then extracted with N hydrohloric acid (40 cc). The hydrochloric acid solution is made alkaline to phenolphthalein with sodium hydroxide (d = 1.33).The base which separates is extracted with chloroform (50 cc). The chloroform solution is dried over anhydrous sodium sulfate and then evaporated to dryness. There are obtained 5-[3-(4-β-hydroxyethylpiperazino)propyl]dibenzazepine (7.95g), the dihydrochloride of which, crystallized from ethanol, melts at about 210°C.

Therapeutic Function

Antidepressant, Antipsychotic

OPIPRAMOL Preparation Products And Raw materials

Raw materials

Preparation Products

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OPIPRAMOL Suppliers

Ariheet Pharmachem Llp
Tel
--
Fax
--
Country
India
ProdList
22
Advantage
58
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View Lastest Price from OPIPRAMOL manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
OPIPRAMOL 315-72-0
Price
US $1.00/G
Min. Order
1G
Purity
99%
Supply Ability
1KG
Release date
2024-05-21

315-72-0, OPIPRAMOLRelated Search:


  • NSC 169867
  • OPIPRAMOL
  • 4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol
  • N-[3-[4-(2-hydroxyethyl)piperazino]propyl]iminostilbene
  • 1-Piperazineethanol, 4-3-(5H-dibenzb,fazepin-5-yl)propyl-
  • 4-(3-(DIBENZ(B,F)AZEPIN-5-YL)PROPYL)-1-PIPERAZINEETHANOL
  • G-33040
  • GR-33040
  • Nisidana
  • Opramidol
  • 2-[4-(3-benzo[b][1]benzazepin-11-ylpropyl)piperazin-1-yl]ethanol
  • Opipramol in acetonitrile
  • 315-72-0
  • C23H29N3O
  • C23H25D4N3O
  • Intermediates & Fine Chemicals
  • Pharmaceuticals