DIETHYL 2-ANILINOMALONATE
- Product Name
- DIETHYL 2-ANILINOMALONATE
- CAS No.
- 6414-58-0
- Chemical Name
- DIETHYL 2-ANILINOMALONATE
- Synonyms
- Diethyl 2-(phenylamino);DIETHYL 2-ANILINOMALONATE;DIETHYL 2-PHENYLAMINOMALONATE;diethyl 2-anilinopropanedioate;2-Anilinomalonic acid diethyl ester;Diethyl 2-(phenylamino)malonate 95+%;2-Phenylamino-malonic acid diethyl ester;2-(Phenylamino)propanedioic acid diethyl ester;1H-Pyrazole,5-bromo-1-(tetrahydro-2H-pyran-4-yl)-;Propanedioic acid, 2-(phenylamino)-, 1,3-diethyl ester
- CBNumber
- CB0507130
- Molecular Formula
- C13H17NO4
- Formula Weight
- 251.28
- MOL File
- 6414-58-0.mol
DIETHYL 2-ANILINOMALONATE Property
- Melting point:
- 43-45 °C
- Boiling point:
- 340.6±22.0 °C(Predicted)
- Density
- 1.167±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 14.73±0.59(Predicted)
- Appearance
- White to off-white Solid
Safety
- HazardClass
- IRRITANT
- HS Code
- 2922390090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- AS68228
- Product name
- Diethyl 2-(phenylamino)malonate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $160
- Updated
- 2021/12/16
- Product number
- 7283AE
- Product name
- 2-Phenylamino-malonicaciddiethylester
- Packaging
- 1g
- Price
- $194
- Updated
- 2021/12/16
- Product number
- 059213
- Product name
- 2-Phenylamino-malonic acid diethyl ester
- Purity
- 95+%
- Packaging
- 1g
- Price
- $284
- Updated
- 2021/12/16
- Product number
- AS68228
- Product name
- Diethyl 2-(phenylamino)malonate
- Purity
- 95+%
- Packaging
- 5G
- Price
- $557
- Updated
- 2021/12/16
- Product number
- 7283AE
- Product name
- 2-Phenylamino-malonicaciddiethylester
- Packaging
- 5g
- Price
- $612
- Updated
- 2021/12/16
DIETHYL 2-ANILINOMALONATE Chemical Properties,Usage,Production
Synthesis
685-87-0
6414-58-0
(1) Synthesis of diethyl anilino malonate: Aniline (18.6 g, 0.20 mol) was dissolved in anhydrous benzene (125 mL), followed by the addition of diethyl bromomalonate (23.9 g, 0.10 mol). The reaction mixture was heated to reflux under continuous stirring and maintained for 37 hours. Upon completion of the reaction, the reaction mixture was washed with dilute hydrochloric acid to remove unreacted aniline. The organic layer was separated, washed three times with water and dried with anhydrous magnesium sulfate. Subsequently, the solvent was removed by distillation under reduced pressure. The crude product was purified by silica gel column chromatography using hexane/ethyl acetate (10:1, v/v) as eluent to afford 7.5 g (30% yield) of diethyl anilino malonate. The product was characterized by nuclear magnetic resonance (NMR) with the following data: 1H NMR (δ, TMS, CCl4): 1.20 (6H, t, J = 7 Hz), 4.20 (4H, q, J = 7 Hz), 4.66 (2H, s, br; changed to 1H after addition of D2O), 6.5-7.3 (5H, m).
References
[1] Patent: US4421914, 1983, A
DIETHYL 2-ANILINOMALONATE Preparation Products And Raw materials
Raw materials
Preparation Products
DIETHYL 2-ANILINOMALONATE Suppliers
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