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DIETHYL 2-ANILINOMALONATE

Product Name
DIETHYL 2-ANILINOMALONATE
CAS No.
6414-58-0
Chemical Name
DIETHYL 2-ANILINOMALONATE
Synonyms
Diethyl 2-(phenylamino);DIETHYL 2-ANILINOMALONATE;DIETHYL 2-PHENYLAMINOMALONATE;diethyl 2-anilinopropanedioate;2-Anilinomalonic acid diethyl ester;Diethyl 2-(phenylamino)malonate 95+%;2-Phenylamino-malonic acid diethyl ester;2-(Phenylamino)propanedioic acid diethyl ester;1H-Pyrazole,5-bromo-1-(tetrahydro-2H-pyran-4-yl)-;Propanedioic acid, 2-(phenylamino)-, 1,3-diethyl ester
CBNumber
CB0507130
Molecular Formula
C13H17NO4
Formula Weight
251.28
MOL File
6414-58-0.mol
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DIETHYL 2-ANILINOMALONATE Property

Melting point:
43-45 °C
Boiling point:
340.6±22.0 °C(Predicted)
Density 
1.167±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
14.73±0.59(Predicted)
Appearance
White to off-white Solid
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Safety

HazardClass 
IRRITANT
HS Code 
2922390090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS68228
Product name
Diethyl 2-(phenylamino)malonate
Purity
95+%
Packaging
1g
Price
$160
Updated
2021/12/16
AK Scientific
Product number
7283AE
Product name
2-Phenylamino-malonicaciddiethylester
Packaging
1g
Price
$194
Updated
2021/12/16
Matrix Scientific
Product number
059213
Product name
2-Phenylamino-malonic acid diethyl ester
Purity
95+%
Packaging
1g
Price
$284
Updated
2021/12/16
Activate Scientific
Product number
AS68228
Product name
Diethyl 2-(phenylamino)malonate
Purity
95+%
Packaging
5G
Price
$557
Updated
2021/12/16
AK Scientific
Product number
7283AE
Product name
2-Phenylamino-malonicaciddiethylester
Packaging
5g
Price
$612
Updated
2021/12/16
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DIETHYL 2-ANILINOMALONATE Chemical Properties,Usage,Production

Synthesis

685-87-0

6414-58-0

(1) Synthesis of diethyl anilino malonate: Aniline (18.6 g, 0.20 mol) was dissolved in anhydrous benzene (125 mL), followed by the addition of diethyl bromomalonate (23.9 g, 0.10 mol). The reaction mixture was heated to reflux under continuous stirring and maintained for 37 hours. Upon completion of the reaction, the reaction mixture was washed with dilute hydrochloric acid to remove unreacted aniline. The organic layer was separated, washed three times with water and dried with anhydrous magnesium sulfate. Subsequently, the solvent was removed by distillation under reduced pressure. The crude product was purified by silica gel column chromatography using hexane/ethyl acetate (10:1, v/v) as eluent to afford 7.5 g (30% yield) of diethyl anilino malonate. The product was characterized by nuclear magnetic resonance (NMR) with the following data: 1H NMR (δ, TMS, CCl4): 1.20 (6H, t, J = 7 Hz), 4.20 (4H, q, J = 7 Hz), 4.66 (2H, s, br; changed to 1H after addition of D2O), 6.5-7.3 (5H, m).

References

[1] Patent: US4421914, 1983, A

DIETHYL 2-ANILINOMALONATE Preparation Products And Raw materials

Raw materials

Preparation Products

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DIETHYL 2-ANILINOMALONATE Suppliers

China 16 India 1 United Kingdom 2 United States 6 Global 25
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Advanced Chemical Intermediates Ltd.
Tel
--
Fax
--
Email
enquiries@acints.com
Country
United States
ProdList
4893
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Ryan Scientific, Inc.
Tel
--
Fax
--
Email
ryan.reichlyn@ryansci.com
Country
United States
ProdList
6439
Advantage
60

6414-58-0, DIETHYL 2-ANILINOMALONATERelated Search:

TIMTEC-BB SBB006857 N-PHENYLGLYCINE ETHYL ESTER TIMTEC-BB SBB006901 2-AMINODIETHYLMALONATE DIETHYL 2-(4-CHLOROANILINO)MALONATE DIMETHYL 2-AMINOMALONATE, TECH DIETHYL 2-ANILINOMALONATE Aminomalonic acid

  • Diethyl 2-(phenylamino)malonate 95+%
  • diethyl 2-anilinopropanedioate
  • DIETHYL 2-ANILINOMALONATE
  • DIETHYL 2-PHENYLAMINOMALONATE
  • 2-(Phenylamino)propanedioic acid diethyl ester
  • 2-Anilinomalonic acid diethyl ester
  • 2-Phenylamino-malonic acid diethyl ester
  • Diethyl 2-(phenylamino)
  • Propanedioic acid, 2-(phenylamino)-, 1,3-diethyl ester
  • 1H-Pyrazole,5-bromo-1-(tetrahydro-2H-pyran-4-yl)-
  • 6414-58-0