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ChemicalBook > CAS DataBase List > 3-TERT-BUTYLISOXAZOL-5-AMINE

3-TERT-BUTYLISOXAZOL-5-AMINE

Uses
Product Name
3-TERT-BUTYLISOXAZOL-5-AMINE
CAS No.
59669-59-9
Chemical Name
3-TERT-BUTYLISOXAZOL-5-AMINE
Synonyms
5-AMINO-3-T-BUTYL ISOXAZOLE;3-TERT-BUTYL-5-ISOXAZOLAMINE;3-TERT-BUTYLISOXAZOL-5-AMINE;3-tert-butylisoxazole-5-aMine;3-tert-Butyl-isoxazol-5-ylamine;3-tert-butyl-1,2-oxazol-5-aMine;5-Amino-3-(tert-butyl)isoxazole;3-tert-Butylisoxazol-5-amine ,97%;5-Isoxazolamine, 3-(1,1-dimethylethyl)-;3-(tert-Butyl)isoxazol-5-amine, 5-Amino-3-(tert-butyl)-1,2-oxazole
CBNumber
CB0511722
Molecular Formula
C7H12N2O
Formula Weight
140.18
MOL File
59669-59-9.mol
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3-TERT-BUTYLISOXAZOL-5-AMINE Property

Boiling point:
248.1±28.0 °C(Predicted)
Density 
1.042±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
-0.31±0.50(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C7H12N2O/c1-7(2,3)5-4-6(8)10-9-5/h4H,8H2,1-3H3
InChIKey
APHNQOGPYLTSFX-UHFFFAOYSA-N
SMILES
O1C(N)=CC(C(C)(C)C)=N1
CAS DataBase Reference
59669-59-9
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Safety

Risk Statements 
20/21/22
Safety Statements 
36/37-24/25
RIDADR 
2811
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B809685
Product name
3-tert-Butylisoxazol-5-amine
Packaging
50mg
Price
$60
Updated
2021/12/16
TRC
Product number
B809685
Product name
3-tert-Butylisoxazol-5-amine
Packaging
250mg
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-A7
Product name
5-Amino-3-(tert-butyl)isoxazole
Packaging
1g
Price
$26
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB13151
Product name
3-tert-Butyl-isoxazol-5-ylamine
Packaging
1g
Price
$65
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK125218
Product name
3-tert-Butylisoxazol-5-amine
Purity
97%
Packaging
250mg
Price
$73
Updated
2021/12/16
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3-TERT-BUTYLISOXAZOL-5-AMINE Chemical Properties,Usage,Production

Uses

3-tert-butylisoxazol-5-amine is a useful research chemical.

Chemical Properties

White solid

Synthesis

59997-51-2

59669-59-9

GENERAL STEPS: To a configured aqueous sodium hydroxide solution (40.00 g, 1 mol, dissolved in 200 mL of water) were sequentially added hydroxylamine hydrochloride (24.00 g, 346 mmol) and 4,4-dimethyl-3-oxovaleronitrile (40.00 g, 320 mmol). The reaction mixture was stirred at a constant temperature at 50 °C for 3 hours. After completion of the reaction, the mixture was cooled to room temperature and the precipitated white crystalline solid was collected by filtration. The solid was washed several times with cold water and subsequently dried to afford the target compound 3-tert-butylisoxazol-5-amine as a white crystalline solid (34 g, 76% yield). The product was characterized by 1H NMR (DMSO-d6): δ 6.41 (brs, 2H), 4.85 (s, 1H), 1.18 (s, 9H); LC-MS (ES, m/z) analysis showed that the [M + H]+ peak was located at 141.3.

References

[1] Heterocycles, 1991, vol. 32, # 6, p. 1153 - 1158
[2] Journal of Medicinal Chemistry, 2012, vol. 55, # 3, p. 1082 - 1105
[3] Patent: US2008/261961, 2008, A1. Location in patent: Page/Page column 16
[4] Organic Letters, 2018, vol. 20, # 9, p. 2774 - 2777
[5] Journal of Medicinal Chemistry, 2016, vol. 59, # 18, p. 8293 - 8305

3-TERT-BUTYLISOXAZOL-5-AMINE Preparation Products And Raw materials

Raw materials

Sodium sulfate Chloroform Pivaloylacetonitrile Sodium hydroxide Hydroxylamine sulfate

Preparation Products

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3-TERT-BUTYLISOXAZOL-5-AMINE Suppliers

Canada 1 China 88 China Hong Kong 1 Germany 3 India 1 Ukraine 1 United Kingdom 2 United States 15 Global 112
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from 3-TERT-BUTYLISOXAZOL-5-AMINE manufacturers

Career Henan Chemical Co
Product
3-TERT-BUTYLISOXAZOL-5-AMINE 59669-59-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-01

59669-59-9, 3-TERT-BUTYLISOXAZOL-5-AMINERelated Search:

DI(T-BUTYLAMINO)SILANE 2,6-Di-tert-butylphenol 3-TERT-BUTYLISOXAZOL-5-AMINE HYDROCHLORIDE 5-TERT-BUTYLISOXAZOL-3-AMINE METHYL 3-TERT-BUTYL-5-AMINOISOXAZOLE-4-CARBOXYLATE 2,6-Dimethoxy-N-(3-(2-methoxy-1,1-dimethylethyl)-5-isoxazolyl)benzanam ide 3-(adamantan-1-yl)-1,2-oxazol-5-amine N-(3-TERT-BUTYL-ISOXAZOL-5-YL)-2-CHLORO-ACETAMIDE IFLAB-BB F2108-0166 3-TERT-BUTYLISOXAZOL-5-AMINE

  • 3-(tert-Butyl)isoxazol-5-amine, 5-Amino-3-(tert-butyl)-1,2-oxazole
  • 3-TERT-BUTYLISOXAZOL-5-AMINE
  • 3-tert-Butyl-isoxazol-5-ylamine
  • 3-tert-Butylisoxazol-5-amine ,97%
  • 5-Amino-3-(tert-butyl)isoxazole
  • 3-tert-butylisoxazole-5-aMine
  • 3-tert-butyl-1,2-oxazol-5-aMine
  • 5-AMINO-3-T-BUTYL ISOXAZOLE
  • 5-Isoxazolamine, 3-(1,1-dimethylethyl)-
  • 3-TERT-BUTYL-5-ISOXAZOLAMINE
  • 59669-59-9
  • CHIRAL CHEMICALS