3-Amino-5-tert-butylisoxazole

Product Name: 3-Amino-5-tert-butylisoxazole
CAS No.: 55809-36-4
Chemical Name: 3-Amino-5-tert-butylisoxazole
Synonyms: TIMTEC-BB SBB005492;3-AMINO-5-T-BUTYLISOXAZOLE;5-TERT-BUTYLISOXAZOL-3-AMINE;3-AMINO-5-TERT-BUTYLISOXAZOLE;5-tert-Butyl-3-isoxazolylamine;5-(tert-Butyl)-3-isoxazolamine;5-TERT-BUTYL-ISOXAZOL-3-YLAMINE;5-tert-butyl-1,2-oxazol-3-aMine;3-Amino-5-tert-butylisoxazole 97%;3-Amino-5-tert-butylisoxazole,97%
CBNumber: CB1455513
Molecular Formula: C7H12N2O
Formula Weight: 140.18
MOL File: 55809-36-4.mol

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3-Amino-5-tert-butylisoxazole Property

Melting point:: 110-114 °C
Boiling point:: 248.1±28.0 °C(Predicted)
Density: 1.042±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 2.37±0.10(Predicted)
color: White to Light yellow
BRN: 1100990
InChI: InChI=1S/C7H12N2O/c1-7(2,3)5-4-6(8)9-10-5/h4H,1-3H3,(H2,8,9)
InChIKey: GGXGVZJHUKEJHO-UHFFFAOYSA-N
SMILES: O1C(C(C)(C)C)=CC(N)=N1
CAS DataBase Reference: 55809-36-4(CAS DataBase Reference)
EPA Substance Registry System: 3-Isoxazolamine, 5-(1,1-dimethylethyl)- (55809-36-4)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38-37/38-36
Safety Statements: 26-36-37
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 666580
Product name: 3-Amino-5-tert-butylisoxazole
Purity: 97%
Packaging: 5g
Price: $67.8
Updated: 2023/06/20

TCI Chemical

Product number: A2341
Product name: 3-Amino-5-tert-butylisoxazole
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $101
Updated: 2025/07/31

TCI Chemical

Product number: A2341
Product name: 3-Amino-5-tert-butylisoxazole
Purity: >97.0%(GC)(T)
Packaging: 25g
Price: $474
Updated: 2021/12/16

TRC

Product number: A617618
Product name: 3-Amino-5-tert-butylisoxazole
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 021406
Product name: 3-Amino-5-tert-butylisoxazole
Purity: 97%
Packaging: 1g
Price: $10
Updated: 2021/12/16

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3-Amino-5-tert-butylisoxazole Chemical Properties,Usage,Production

Uses

Amination of aryl bromides catalyzed by Pd(dba)3 (Aldrich Catalog No. 328774) and Xantphos (Aldrich Catalog No. 526460).1

Uses

Amination of aryl bromides catalyzed by Pd(dba)₃ (Aldrich Catalog No. 328774) and Xantphos (Aldrich Catalog No. 526460).

Uses

3-Amino-5-tert-butylisoxazole is a degradation product of herbicide isouron.

Synthesis

59997-51-2

55809-36-4

Example 1: Gaseous hydrogen chloride (26.3 g) was added to 4,4-dimethyl-3-oxopentanenitrile (75.102 g) suspended in a mixture of anhydrous toluene (150 ml) and anhydrous methanol (26.7 ml) at 5° C. to 10° C. with continuous stirring. Subsequently, the reaction mixture was allowed to stand at 10° to 12°C for 23 hours. Under cooling and stirring conditions, anhydrous methanol (750 ml) followed by triethylamine (185.178 g) was added slowly and dropwise to the reaction mixture until a complete solution was formed. Next, hydroxylamine sulfate (51.704 g) was added and the reaction mixture was stirred at 50°C for 2 hours. After completion of the reaction, the mixture was concentrated. Hydrochloric acid (112.629 g) was added dropwise to the concentrated mixture and stirring was continued at 50 °C for 1 hour. After removal of the solvent by evaporation under reduced pressure, the residue was adjusted to alkaline with 48% aqueous sodium hydroxide solution under cooling conditions, followed by extraction of the aqueous solution with toluene. After the organic layer was washed with water, the solvent was removed by azeotropic distillation at atmospheric pressure and finally dried to give 3-amino-5-tert-butylisoxazole (79.480 g) with a melting point of 106° to 109°C and a yield of 94.5%.

References

[1] Patent: US4200757, 1980, A
[2] Patent: WO2013/100632, 2013, A1. Location in patent: Page/Page column 42; 43
[3] Patent: US2014/371219, 2014, A1. Location in patent: Paragraph 0288; 0289; 0290
[4] Molecules, 2014, vol. 19, # 2, p. 2004 - 2028
[5] Heterocycles, 1991, vol. 32, # 6, p. 1153 - 1158

3-Amino-5-tert-butylisoxazole Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Amino-5-tert-butylisoxazole Suppliers

Americas 1 Canada 1 China 163 Europe 1 Germany 4 India 7 Japan 2 Slovakia 1 Switzerland 1 United Kingdom 13 United States 27 Global 221

Suzhou TaCheng Pharmaceutical Co., Ltd.

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Energy Chemical

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View Lastest Price from 3-Amino-5-tert-butylisoxazole manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: 3-Amino-5-tert-butylisoxazole 55809-36-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 2000
Release date: 2025-09-10

R&D Scientific Inc.

Product: 3-Amino-5-tert-butylisoxazole 55809-36-4
Price: US $520.00/g
Min. Order: 1g
Purity: 97
Supply Ability: 500 Kg
Release date: 2024-02-29

henan kanbei chemical co.,ltd

Product: 3-Amino-5-tert-butylisoxazole 55809-36-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2022-09-26

55809-36-4, 3-Amino-5-tert-butylisoxazoleRelated Search:

tert-Butyl methyl ether tert-Butanol 4-tert-Butylcatechol Glycine Methyl 4-tert-butylbenzoate tert-Butylchlorodiphenylsilane Sulfisoxazole 6-Aminocaproic acid 3-Aminophenol Sulfamethoxazole tert-Butyldimethylsilyl chloride tert-Butyl hydroperoxide tert-Butylhydroquinone ALTRENOGEST 4-tert-Butylphenol ISOXAFLUTOLE Isoxazole Tris(hydroxymethyl)aminomethane

TIMTEC-BB SBB005492

5-TERT-BUTYLISOXAZOL-3-AMINE

5-TERT-BUTYL-ISOXAZOL-3-YLAMINE

5-(1,1-dimethylethyl)-3-isoxazolamine

3-AMINO-5-TERT-BUTYLISOXAZOLE

3-AMINO-5-T-BUTYLISOXAZOLE

3-Amino-5-tert-butylisoxazole,97%

3-Amino-5-tert-butylisoxazole 97%

5-tert-butyl-1,2-oxazol-3-aMine

5-tert-Butyl-3-isoxazolylamine

5-(tert-Butyl)isoxazol-3-amine, 5-(tert-Butyl)-1,2-oxazol-3-amine

3-Amino-5-tert-butylisoxazole &gt

3-Isoxazolamine, 5-(1,1-dimethylethyl)-

3-Amino-5-<i>tert</i>-butylisoxazole

5-(tert-Butyl)-3-isoxazolamine

55809-36-4

AMINO

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