Isoxazole

Product Name: Isoxazole
CAS No.: 288-14-2
Chemical Name: Isoxazole
Synonyms: ISOXAZOLE;Isoxazolec;Isooxazole;1,2-Oxazole;Isoxazole>Isoxazole,99%;Isoxazole 99%;ISOXAZOLE 98+%;Isoxazole, 98.5%;Different oxazole
CBNumber: CB3485864
Molecular Formula: C3H3NO
Formula Weight: 69.06
MOL File: 288-14-2.mol

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Isoxazole Property

Melting point:: -67.1°C
Boiling point:: 93-95 °C(lit.)
Density: 1.078 g/mL at 25 °C(lit.)
vapor density: 2.4 (vs air)
refractive index: n20/D 1.427(lit.)
Flash point:: 48 °F
storage temp.: 2-8°C
solubility: 167g/l
pka: -2.0(at 25℃)
form: clear liquid
color: Colorless to Light yellow
BRN: 103773
InChIKey: CTAPFRYPJLPFDF-UHFFFAOYSA-N
CAS DataBase Reference: 288-14-2(CAS DataBase Reference)
NIST Chemistry Reference: Isoxazole(288-14-2)
EPA Substance Registry System: Isoxazole (288-14-2)

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Safety

Hazard Codes: F,Xi
Risk Statements: 11
Safety Statements: 16-23/33-33-29-7/9
RIDADR: UN 1993 3/PG 2
WGK Germany: 3
F: 10
Hazard Note: Highly Flammable
TSCA: Yes
HazardClass: 3
PackingGroup: II
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H225Highly Flammable liquid and vapour
Precautionary statements: P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 151637
Product name: Isoxazole
Purity: 99%
Packaging: 5g
Price: $34.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: 151637
Product name: Isoxazole
Purity: 99%
Packaging: 25g
Price: $113
Updated: 2024/03/01

TCI Chemical

Product number: I0372
Product name: Isoxazole
Purity: >95.0%(GC)
Packaging: 5g
Price: $32
Updated: 2024/03/01

Alfa Aesar

Product number: L01607
Product name: Isoxazole, 99%
Packaging: 5g
Price: $26.65
Updated: 2024/03/01

TRC

Product number: I779145
Product name: Isoxazole
Packaging: 100mg
Price: $60
Updated: 2021/12/16

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Isoxazole Chemical Properties,Usage,Production

Description

Isoxazole, an important class of heterocycles, is a five membered heterocyclic compound that exhibits various pharmacological actions. It is present in some natural products such as ibotenic acid and is also used as a foundation for several drugs such as the COX-2 inhibitor valdecoxib and anti-inflammatory drugs. Isoxazoles are largely applied in the area of pharmaceuticals and therapeutics, including insecticidal, antibacterial, antibiotic, antitumour, antifungal, antituberculosis, anticancer and ulcerogenic. Besides, it has a great effect on reducing blood glucose, eliminating pain, resisting inflammation, killing harmful bacteria, controlling and reducing the risk of HIV.

Chemical Properties

A colorless liquid resembling pyridine. It is soluble in water at room temperature up to six times its volume.

Uses

Natural insecticide.

Definition

ChEBI: Isoxazole is a monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles. It is a mancude organic heteromonocyclic parent, a monocyclic heteroarene and a member of isoxazoles.

Preparation

Isoxazoles can be synthesized by various methods, such as the 1,3-dipolar cycloaddition reaction of nitrile oxides with alkynes, the reaction of hydroxylamine with 1,3-diketones or propiolic acid derivatives, etc.
www.organic-chemistry.org

General Description

Isoxazole(288-14-2) are described as inhibitors of acetylcholinesterase (AChE). Isoxazole ligands bind to and inhibit the Sxc- antiporter.

Hazard

Narcotic and psychomimetic effects.

References

https://en.wikipedia.org/wiki/Isoxazole
https://pubchem.ncbi.nlm.nih.gov/compound/9254

Isoxazole Preparation Products And Raw materials

Raw materials

Malonaldehyde bis(diethyl acetal) Hydroxylamine hydrochloride

Preparation Products

Zonisamide 2-Amino-5-chlorobenzophenone Clomazone 2-AMINO-5-CHLOROBENZOPHENONE OXIME 5-Chloro-2-(methylamino)benzophenone SULFISOXAZOLE ACETYL (200 MG) Isazophos 6-CHLORO-2-(CHLOROMETHYL)-3-OXIDO-4-PHENYL-QUINAZOLINE Risperidone Oxacillin sodium monohydrate

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Isoxazole Suppliers

Americas 1 Belgium 3 China 146 Czech Republic 1 Europe 3 France 1 Germany 7 India 27 Japan 3 Switzerland 3 United Kingdom 14 United States 42 Global 251

Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.

Tel: 133-96369453 18678026865
Fax: 0536-2101172
Email: sdfantai@163.com
Country: China
ProdList: 852
Advantage: 58

Weifang Siyuan Chemical Co., Ltd.

Tel: 0536-8888106 17663601818
Fax: 0536-8888106
Email: 2354379876@qq.com
Country: China
ProdList: 244
Advantage: 58

Weifang Weimeng Chemical Co., Ltd.

Tel: 0536-8790166 15105445095
Email: weimengchem@163.com
Country: China
ProdList: 459
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

BeiJing Hwrk Chemicals Limted

Tel: 0757-86329057 18501085097
Fax: 010-89508210
Email: sales3.gd@hwrkchemical.com
Country: China
ProdList: 7583
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

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View Lastest Price from Isoxazole manufacturers

Career Henan Chemical Co

Product: Isoxazole 288-14-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-24

288-14-2, IsoxazoleRelated Search:

5-Methyl-4-isoxazolecarboxylic acid Fenoxaprop-P Famoxadone 3,5-Dimethylisoxazole METHYL ISOXAZOLE-5-CARBOXYLATE ISOXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER C-ISOXAZOL-3-YL-METHYLAMINE ISOXAZOLE-5-CARBONYL CHLORIDE 4-Methylvaleryl chloride Isoxazol-4-ylmethanamine oxalate ISOXAFLUTOLE ISOXAZOLO[5,4-B]PYRIDIN-3-YLAMINE 5-Isoxazolecarboxylicacid,ethylester(9CI) ISOXAZOLE-5-CARBOXYLIC ACID ISOXAZOLIDIN-3-ONE 1,2-oxazol-3-ylMethanaMine hydrochloride 3-AMINOISOXAZOLO[4,5-B]PYRAZINE Isoxazole-4-boronicacid

ISOXAZOLE

1-Oxa-2-azacyclopentadiene

Isooxazole

ISOXAZOLE 98+%

1,2-Oxazole

Isoxazole,99%

Different oxazole

Isoxazole 99%

Isoxazole, 98.5%

Isoxazole&gt

Isoxazolec

Isoxazole (6CI, 7CI, 8CI, 9CI, ACI)

Entacapone Impurity 31

288-14-2

Isoxazoles

Heterocyclic Building Blocks

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks

Isoxazoles

Building Blocks

Isoxazoles, Oxadiazoles, Oxazoles

pharmacetical

Boronic ester

Isoxazole

Organoborons

Thiophens