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Isoxazole

Product Name
Isoxazole
CAS No.
288-14-2
Chemical Name
Isoxazole
Synonyms
ISOXAZOLE;Isoxazolec;Isooxazole;1,2-Oxazole;Isoxazole>Isoxazole,99%;Isoxazole 99%;ISOXAZOLE 98+%;Isoxazole, 98.5%;Different oxazole
CBNumber
CB3485864
Molecular Formula
C3H3NO
Formula Weight
69.06
MOL File
288-14-2.mol
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Isoxazole Property

Melting point:
-67.1°C
Boiling point:
93-95 °C(lit.)
Density 
1.078 g/mL at 25 °C(lit.)
vapor density 
2.4 (vs air)
refractive index 
n20/D 1.427(lit.)
Flash point:
48 °F
storage temp. 
2-8°C
solubility 
167g/l
pka
-2.0(at 25℃)
form 
clear liquid
color 
Colorless to Light yellow
BRN 
103773
InChIKey
CTAPFRYPJLPFDF-UHFFFAOYSA-N
CAS DataBase Reference
288-14-2(CAS DataBase Reference)
NIST Chemistry Reference
Isoxazole(288-14-2)
EPA Substance Registry System
Isoxazole (288-14-2)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11
Safety Statements 
16-23/33-33-29-7/9
RIDADR 
UN 1993 3/PG 2
WGK Germany 
3
10
Hazard Note 
Highly Flammable
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
151637
Product name
Isoxazole
Purity
99%
Packaging
5g
Price
$34.9
Updated
2024/03/01
Sigma-Aldrich
Product number
151637
Product name
Isoxazole
Purity
99%
Packaging
25g
Price
$113
Updated
2024/03/01
TCI Chemical
Product number
I0372
Product name
Isoxazole
Purity
>95.0%(GC)
Packaging
5g
Price
$32
Updated
2024/03/01
Alfa Aesar
Product number
L01607
Product name
Isoxazole, 99%
Packaging
5g
Price
$26.65
Updated
2024/03/01
TRC
Product number
I779145
Product name
Isoxazole
Packaging
100mg
Price
$60
Updated
2021/12/16
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Isoxazole Chemical Properties,Usage,Production

Description

Isoxazole, an important class of heterocycles, is a five membered heterocyclic compound that exhibits various pharmacological actions. It is present in some natural products such as ibotenic acid and is also used as a foundation for several drugs such as the COX-2 inhibitor valdecoxib and anti-inflammatory drugs. Isoxazoles are largely applied in the area of pharmaceuticals and therapeutics, including insecticidal, antibacterial, antibiotic, antitumour, antifungal, antituberculosis, anticancer and ulcerogenic. Besides, it has a great effect on reducing blood glucose, eliminating pain, resisting inflammation, killing harmful bacteria, controlling and reducing the risk of HIV.

Chemical Properties

A colorless liquid resembling pyridine. It is soluble in water at room temperature up to six times its volume.

Uses

Natural insecticide.

Definition

ChEBI: Isoxazole is a monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles. It is a mancude organic heteromonocyclic parent, a monocyclic heteroarene and a member of isoxazoles.

Preparation

Isoxazoles can be synthesized by various methods, such as the 1,3-dipolar cycloaddition reaction of nitrile oxides with alkynes, the reaction of hydroxylamine with 1,3-diketones or propiolic acid derivatives, etc.
www.organic-chemistry.org

General Description

Isoxazole(288-14-2) are described as inhibitors of acetylcholinesterase (AChE). Isoxazole ligands bind to and inhibit the Sxc- antiporter.

Hazard

Narcotic and psychomimetic effects.

References

https://en.wikipedia.org/wiki/Isoxazole
https://pubchem.ncbi.nlm.nih.gov/compound/9254

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Isoxazole Suppliers

Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
133-96369453 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
862
Advantage
58
Weifang Siyuan Chemical Co., Ltd.
Tel
0536-8888106 17663601818
Fax
0536-8888106
Email
2354379876@qq.com
Country
China
ProdList
245
Advantage
58
Weifang Weimeng Chemical Co., Ltd.
Tel
0536-8790166 15105445095
Email
weimengchem@163.com
Country
China
ProdList
471
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
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View Lastest Price from Isoxazole manufacturers

Career Henan Chemical Co
Product
Isoxazole 288-14-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-12-24

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