ISOXAFLUTOLE
- Product Name
- ISOXAFLUTOLE
- CAS No.
- 141112-29-0
- Chemical Name
- ISOXAFLUTOLE
- Synonyms
- MERLIN;BALANCE;Ift cpd;Hsdb 7275;Isoxautole;Exp 31130a;SOXAFLUTOLE;ISOXAFLUTOLE;Isoxaflutole 0;Isoxaflutole [iso]
- CBNumber
- CB0382227
- Molecular Formula
- C15H12F3NO4S
- Formula Weight
- 359.32
- MOL File
- 141112-29-0.mol
ISOXAFLUTOLE Property
- Melting point:
- 138-138.5° (Cain); mp 140°
- Boiling point:
- 575.1±50.0 °C(Predicted)
- Density
- 1.59
- Flash point:
- >130 °C
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Chloroform, DCM, Ethyl Acetate, Methanol
- pka
- -4.29±0.50(Predicted)
- form
- Solid
- color
- White
- BRN
- 8344543
- LogP
- 2.320
- CAS DataBase Reference
- 141112-29-0
- EPA Substance Registry System
- Isoxaflutole (141112-29-0)
Safety
- Hazard Codes
- Xn,N
- Risk Statements
- 50/53-63
- Safety Statements
- 36/37-60-61
- RIDADR
- UN3077 9/PG 3
- WGK Germany
- 3
- Hazardous Substances Data
- 141112-29-0(Hazardous Substances Data)
- Toxicity
- LD50 in rats, quails, mallard ducks (mg/kg): >5000, >2150, >2150 orally; in rabbits (mg/kg): >2000 dermally (Luscombe)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P391Collect spillage. Hazardous to the aquatic environment
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 46437
- Product name
- Isoxaflutole
- Purity
- PESTANAL?, analytical standard
- Packaging
- 100mg
- Price
- $147
- Updated
- 2024/03/01
- Product number
- I918140
- Product name
- Isoxaflutole
- Packaging
- 10mg
- Price
- $580
- Updated
- 2021/12/16
- Product number
- 71008
- Product name
- Isoxaflutole
- Packaging
- 2.5mg
- Price
- $675
- Updated
- 2021/12/16
- Product number
- AGR0000257
- Product name
- ISOXAFLUTOLE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496
- Updated
- 2021/12/16
- Product number
- CD11263309
- Product name
- (5-Cyclopropylisoxazol-4-yl)(2-(methylsulfonyl)-4-(trifluoromethyl)phenyl)methanone
- Purity
- 95+%
- Packaging
- 1g
- Price
- $89
- Updated
- 2021/12/16
ISOXAFLUTOLE Chemical Properties,Usage,Production
Description
Isoxaflutole is a 4-benzoyl isoxazole molecule and is used as a pre- and early post-emergence herbicide for the control of a wide range of important broadleaf and grass weeds in maize (Zea mays), both in Europe and in North America. It is also registered for use in sugarcane in Central and South America (2–4). It causes characteristic bleaching of newly developed tissues of susceptible species followed by growth cessation and necrosis. Marketed as Balance for corn (maize) in the United States, and Merlin for corn in Europe; and in sugarcane, it mixes well with metolachlor, acetochlor, dimethenamid, and atrazine to complete the weed spectrum and to reduce the application rates of the latter compounds (2). Isoxaflutole also controls triazineresistant weeds in the field (4).
Uses
Isoxaflutole is an pesticide used to selectively control both grass and broad-leaved weeds in maize and sugar cane. Isoxaflutole is known to work by inhibiting the enzyme 4-Hydroxyphenylpyruvate dioxygenase (HPPD) which results in the disruption of pigment biosynthesis.
Uses
Herbicide.
Definition
ChEBI: Isoxaflutole is a member of the class of isoxazoles that is 1,2-oxazole substituted by a 2-(methanesulfonyl)-4-(trifluoromethyl)benzoyl group and a cyclopropyl group at positions 4 and 5, respectively. It is a 4-hydroxyphenylpyruvate dioxygenase inhibitor which is used as a herbicide for weed control in maize and sugarcane. It has a role as an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor, a proherbicide and an agrochemical. It is a member of cyclopropanes, a member of isoxazoles, an aromatic ketone, a member of (trifluoromethyl)benzenes and a sulfone.
Pharmacology
Isoxaflutole is readily taken up by roots and foliar
tissues and then rapidly degraded to a diketonitrile derivative
(2-cyclopropyl-3-(2-mesyl-4-trifluoromethylphenyl)-
3-oxo propanenitrile) , which is translocated
throughout the plant via xylem and phloem (2,3,6,8). It
is this metabolite that inhibits HPPD (7), thereby depleting
the plastoquinone pools in developing leaves. Plastoquinone
is a cofactor in the desaturation of phytoene, levels
of which increase in bleached leaves, concomitant with
decreases in colored carotenoids (6). Although bleaching
is the primary symptom associated with HPPD inhibition,
subsequent growth suppression and necrosis are also
believed to be a consequence (8).
Isoxaflutole also degrades to the diketonitrile derivative
in the soil (3,8). The half-life of isoxaflutole in soil
is dependent on soil type, pH, and moisture, ranging
from 12 hours to 3 days under laboratory conditions (8).
The physicochemical properties of isoxaflutole and of
diketonitrile play an important role in both soil and
herbicidal activity and selectivity (8).
ISOXAFLUTOLE Preparation Products And Raw materials
Raw materials
Preparation Products
ISOXAFLUTOLE Suppliers
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View Lastest Price from ISOXAFLUTOLE manufacturers
- Product
- ISOXAFLUTOLE 141112-29-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.99%
- Supply Ability
- 200kg
- Release date
- 2019-12-23