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ISOXAFLUTOLE

Product Name
ISOXAFLUTOLE
CAS No.
141112-29-0
Chemical Name
ISOXAFLUTOLE
Synonyms
MERLIN;BALANCE;Ift cpd;Hsdb 7275;Isoxautole;Exp 31130a;SOXAFLUTOLE;ISOXAFLUTOLE;Isoxaflutole 0;Isoxaflutole [iso]
CBNumber
CB0382227
Molecular Formula
C15H12F3NO4S
Formula Weight
359.32
MOL File
141112-29-0.mol
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ISOXAFLUTOLE Property

Melting point:
138-138.5° (Cain); mp 140°
Boiling point:
575.1±50.0 °C(Predicted)
Density 
1.59
Flash point:
>130 °C
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform, DCM, Ethyl Acetate, Methanol
form 
neat
pka
-4.29±0.50(Predicted)
color 
White
BRN 
8344543
CAS DataBase Reference
141112-29-0
EPA Substance Registry System
Isoxaflutole (141112-29-0)
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Safety

Hazard Codes 
Xn,N
Risk Statements 
50/53-63
Safety Statements 
36/37-60-61
RIDADR 
UN3077 9/PG 3
WGK Germany 
3
Hazardous Substances Data
141112-29-0(Hazardous Substances Data)
Toxicity
LD50 in rats, quails, mallard ducks (mg/kg): >5000, >2150, >2150 orally; in rabbits (mg/kg): >2000 dermally (Luscombe)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P391Collect spillage. Hazardous to the aquatic environment

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
46437
Product name
Isoxaflutole
Purity
PESTANAL?, analytical standard
Packaging
100mg
Price
$119
Updated
2021/12/16
TRC
Product number
I918140
Product name
Isoxaflutole
Packaging
10mg
Price
$580
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
71008
Product name
Isoxaflutole
Packaging
2.5 mg
Price
$675
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AGR0000257
Product name
ISOXAFLUTOLE
Purity
95.00%
Packaging
5MG
Price
$496
Updated
2021/12/16
Crysdot
Product number
CD11263309
Product name
(5-Cyclopropylisoxazol-4-yl)(2-(methylsulfonyl)-4-(trifluoromethyl)phenyl)methanone
Purity
95+%
Packaging
1g
Price
$89
Updated
2021/12/16
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ISOXAFLUTOLE Chemical Properties,Usage,Production

Description

Isoxaflutole is a 4-benzoyl isoxazole molecule and is used as a pre- and early post-emergence herbicide for the control of a wide range of important broadleaf and grass weeds in maize (Zea mays), both in Europe and in North America. It is also registered for use in sugarcane in Central and South America (2–4). It causes characteristic bleaching of newly developed tissues of susceptible species followed by growth cessation and necrosis. Marketed as Balance for corn (maize) in the United States, and Merlin for corn in Europe; and in sugarcane, it mixes well with metolachlor, acetochlor, dimethenamid, and atrazine to complete the weed spectrum and to reduce the application rates of the latter compounds (2). Isoxaflutole also controls triazineresistant weeds in the field (4).

Uses

Herbicide.

Uses

Isoxaflutole is an pesticide used to selectively control both grass and broad-leaved weeds in maize and sugar cane. Isoxaflutole is known to work by inhibiting the enzyme 4-Hydroxyphenylpyruvate dioxygenase (HPPD) which results in the disruption of pigment biosynthesis.

Pharmacology

Isoxaflutole is readily taken up by roots and foliar tissues and then rapidly degraded to a diketonitrile derivative (2-cyclopropyl-3-(2-mesyl-4-trifluoromethylphenyl)- 3-oxo propanenitrile) , which is translocated throughout the plant via xylem and phloem (2,3,6,8). It is this metabolite that inhibits HPPD (7), thereby depleting the plastoquinone pools in developing leaves. Plastoquinone is a cofactor in the desaturation of phytoene, levels of which increase in bleached leaves, concomitant with decreases in colored carotenoids (6). Although bleaching is the primary symptom associated with HPPD inhibition, subsequent growth suppression and necrosis are also believed to be a consequence (8).
Isoxaflutole also degrades to the diketonitrile derivative in the soil (3,8). The half-life of isoxaflutole in soil is dependent on soil type, pH, and moisture, ranging from 12 hours to 3 days under laboratory conditions (8). The physicochemical properties of isoxaflutole and of diketonitrile play an important role in both soil and herbicidal activity and selectivity (8).

ISOXAFLUTOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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ISOXAFLUTOLE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32358
Advantage
50
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
24711
Advantage
65
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9750
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
sales@topbiochem.com
Country
China
ProdList
10599
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-62063333-1 15601730970
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
24993
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9566
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3755
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
service@targetmol.com
Country
China
ProdList
7941
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9997
Advantage
55
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View Lastest Price from ISOXAFLUTOLE manufacturers

Career Henan Chemical Co
Product
ISOXAFLUTOLE 141112-29-0
Price
US $1.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
200kg
Release date
2019-12-23

141112-29-0, ISOXAFLUTOLERelated Search:


  • MERLIN
  • BALANCE
  • ISOXAFLUTOLE
  • ISOXAFLUTOLE 45% SOLUTION
  • 5-cyclopropyl-4-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]isoxazole
  • isoxaflutole (bsi, pa iso)
  • isoxaflutole (ISO) 5-cyclopropyl-1,2-oxazol-4-yl α,α,α-trifluoro-2-mesyl-p-tolyl ketone
  • Isoxaflutole 0
  • Isoxautole
  • (5-Cyclopropyl-4-isoxazolyl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]methanone
  • Einecs annex I index 606-054-00-7
  • Exp 31130a
  • Hsdb 7275
  • Ift cpd
  • Isoxaflutole [iso]
  • Isoxaflutole 100mg [141112-29-0]
  • (5-Cyclopropylisoxazol-4-yl)(2-(methylsulfonyl)-4-(trifluoromethyl)phenyl)methanone
  • Isoxaflutole 97% TC
  • Isoxaflutole pesticide
  • Isoxautole Solution,100ppm
  • SOXAFLUTOLE
  • Isoxaflutole@100 μg/mL in AcCN
  • Methanone, (5-cyclopropyl-4-isoxazolyl)[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]-
  • 5-cyclopropyl-4-[2-methanesulfonyl-4-(trifluorome thyl)benzoyl]-1,2-oxazole
  • Isoxaflutole Solution in Acetonitrile, 1000μg/mL
  • 141112-29-0