ChemicalBook > CAS DataBase List > DSP-2230

DSP-2230

Product Name
DSP-2230
CAS No.
1233231-30-5
Chemical Name
DSP-2230
Synonyms
DSP-2230;DSP-2230, 10 mM in DMSO;DSP2230; DSP 2230; DSP-2230;Inhibitor,inhibit,Na+ channels,Sodium Channel,DSP 2230,Na channels,DSP2230,DSP-2230;(2S)-2-({[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}amino)propanamide;Propanamide, 2-[[[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl]amino]-, (2S)-
CBNumber
CB05417694
Molecular Formula
C20H20F3N5O2
Formula Weight
419.4
MOL File
1233231-30-5.mol
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DSP-2230 Property

Boiling point:
607.8±55.0 °C(Predicted)
Density 
1.53±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:125.0(Max Conc. mg/mL);298.04(Max Conc. mM)
form 
Solid
pka
15.94±0.50(Predicted)
color 
White to off-white
InChIKey
HHXCJIMPEJSJTG-JTQLQIEISA-N
SMILES
C(N)(=O)[C@@H](NCC1=NC2=CC=C(OC3=CC(F)=C(F)C(F)=C3)N=C2N1C1CCC1)C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0089255
Product name
DSP-2230
Purity
98.33%
Packaging
5mg
Price
$120
Updated
2021/12/16
ChemScene
Product number
CS-0089255
Product name
DSP-2230
Purity
98.33%
Packaging
10mg
Price
$200
Updated
2021/12/16
ChemScene
Product number
CS-0089255
Product name
DSP-2230
Purity
98.33%
Packaging
25mg
Price
$400
Updated
2021/12/16
ChemScene
Product number
CS-0089255
Product name
DSP-2230
Purity
98.33%
Packaging
50mg
Price
$650
Updated
2021/12/16
ChemScene
Product number
CS-0089255
Product name
DSP-2230
Purity
98.33%
Packaging
100mg
Price
$1050
Updated
2021/12/16
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DSP-2230 Chemical Properties,Usage,Production

Uses

DSP-2230 is a selective Nav1.7/Nav1.8 blocker, can be used to improve neuropathic pain[1][2][3].

IC 50

Nav1.7; Nav1.8

References

[1] Bagal SK, et al. Voltage gated sodium channels as drug discovery targets. Channels (Austin). 2015;9(6):360-6. DOI:10.1080/19336950.2015.1079674
[2] Sara Sabina Hadida-Ruah, et al. Sulfonamides as modulators of sodium channels.
[3] Matthew Alsaloum, et al. Status of peripheral sodium channel blockers for non-addictive pain treatment. Nat Rev Neurol. 2020 Dec;16(12):689-705. DOI:10.1038/s41582-020-00415-2

DSP-2230 Preparation Products And Raw materials

Raw materials

Preparation Products

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DSP-2230 Suppliers

Fujian boshi pharmaceutical technology co. LTD
Tel
0595-22008920; 18120708884
Email
393612455@qq.com
Country
China
ProdList
255
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4817
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9505
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30227
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58

1233231-30-5, DSP-2230Related Search:


  • DSP-2230
  • DSP2230; DSP 2230; DSP-2230
  • Inhibitor,inhibit,Na+ channels,Sodium Channel,DSP 2230,Na channels,DSP2230,DSP-2230
  • Propanamide, 2-[[[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl]amino]-, (2S)-
  • (2S)-2-({[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}amino)propanamide
  • DSP-2230, 10 mM in DMSO
  • 1233231-30-5