FAF1 antibody
Source Reactivity Background References- Product Name
- FAF1 antibody
- Chemical Name
- FAF1 antibody
- Synonyms
- FAF1 antibody
- CBNumber
- CB05626496
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb10638
- Product name
- FAF1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb27552
- Product name
- FAF1 antibody
- Purity
- Immunogen affinity purified.
- Packaging
- 100μg
- Price
- $523.6
- Updated
- 2021/12/16
- Product number
- orb10638
- Product name
- FAF1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
FAF1 antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat
Background
FAF1 was originally identified though yeast two-hybrid screening, interacting with the cytoplasmic domain of Fas, a member of the TNF receptor superfamily that plays a critical role in in apoptosis during development and immune function. FAF1 is widely expressed with highest expression observed in testis, skeletal muscle and heart. FAF1 potentiates Fas-mediated apoptosis and may induce apoptosis without Fas stimulation in some cell types. It does not contain typical death motifs, but rather has two amino-terminal domains with structural homology to ubiquitin. While the precise role of FAF1 during apoptosis is still unclear, it has been observed to be one of the components of the death-inducing signaling complex during Fas-mediated apoptosis and can bind to caspase-8 and FADD. FAF1 has also been shown to suppress the activation of the NF-kappaB transcription factor.
References
[1] Chu, K. et al. (1995) Proc Natl Acad Sci U S A 92, 11894-8.
[2] Ryu, S.W. et al. (1999) Biochem Biophys Res Commun 262, 388-94.
[3] Ryu, S.W. et al. (2003) J Biol Chem 278, 24003-10.
[4] Park, M.Y. et al. (2004) J Biol Chem 279, 2544-9.
FAF1 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
FAF1 antibody Suppliers
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