Applications Immunogen Background

OTUB1 antibody

Applications Immunogen Background
Product Name
OTUB1 antibody
Chemical Name
OTUB1 antibody
Synonyms
OTUB1 antibody;Rabbit Polyclonal OTUB1 Antibody
CBNumber
CB05669196
Formula Weight
0
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb158068
Product name
OTUB1 antibody
Purity
Affinity purified by Protein A
Packaging
100μg
Price
$421.6
Updated
2021/12/16
Biorbyt Ltd
Product number
orb158068
Product name
OTUB1 antibody
Purity
Affinity purified by Protein A
Packaging
200μg
Price
$673.2
Updated
2021/12/16
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OTUB1 antibody Chemical Properties,Usage,Production

Applications

OTUB1 antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity.

Immunogen

Anti-human OTUB1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human OTUB1 protein 1-271 amino acids purified from E. coli.

Background

Otubain 1 (OTUB1) belongs to the ovarian tumor (OUT) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system through its interaction with a ubiquitin protease and E3 ubiquitin ligase. OTUB1 is a highly specific ubiquitin iso-peptidase, it cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. OTUB1 is believed to work in specific ubiquitin-dependent pathways, possibly by providing an editing function of polyubiquitin chain growth. OTUB1 is a hydrolase that removes conjugated ubiquitin from proteins in vitro and may therefore have a significant regulatory role in the level of protein turnover by preventing degradation. Additionally, OTUB1 is a regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered impassive to antigen re-challenge and no longer respond to their cognate antigen. OTUB1 acts via its interaction with RNF128/GRAIL, which is an essential inductor of CD4 T-cell anergy.

OTUB1 antibody Preparation Products And Raw materials

Raw materials

Preparation Products

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OTUB1 antibody Suppliers

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