Rab25 antibody
Source Reactivity Background References- Product Name
- Rab25 antibody
- Chemical Name
- Rab25 antibody
- Synonyms
- Rab25 antibody;Rabbit Polyclonal RAB25 Antibody
- CBNumber
- CB05677887
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb100347
- Product name
- Rab25 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb100347
- Product name
- Rab25 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
Rab25 antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human
Background
Rab11a, Rab11b, and Rab25 are members of the Rab11 subfamily of small Ras-like GTPases. Unlike universally expressed Rab11, typical Rab25 expression appears to be limited to gastrointestinal mucosa, kidney, and lung. Rab25 can associate with apical recycling vesicles to help regulate apical vesicle trafficking. Research studies indicate that atypical Rab25 expression can be associated with various forms of cancer. Increased Rab25 expression is associated with aggressive growth in ovarian and breast cancer, where Rab25 may inhibit apoptosis and promote cancer cell proliferation and invasion through regulation of vesicle transport and cellular motility. Interaction between Rab25 and β1 integrin promotes vesicle-mediated transport of integrin to pseudopodial tip membranes, fostering the persistent invasion of tumor cells. Conversely, the reported loss of Rab25 expression in a number of breast cancer cases has an unclear effect on cancer pathogenesis.
References
[1] Goldenring, J.R. et al. (1993) J Biol Chem 268, 18419-22.
[2] Casanova, J.E. et al. (1999) Mol Biol Cell 10, 47-61.
[3] Wang, X. et al. (2000) J Biol Chem 275, 29138-46.
[4] Cheng, K.W. et al. (2004) Nat Med 10, 1251-6.
[5] Cheng, K.W. et al. (2005) Cancer Res 65, 2516-9.
[6] Chia, W.J. and Tang, B.L. (2009) Biochim Biophys Acta 1795, 110-6.
[7] Tang, B.L. and Ng, E.L. (2009) Cell Motil Cytoskeleton 66, 365-70.
[8] Caswell, P.T. et al. (2007) Dev Cell 13, 496-510.
[9] Cheng, J.M. et al. (2010) Int J Cancer 126, 2799-812.
Rab25 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
Rab25 antibody Suppliers
- Tel
- 18007124176 19384116026
- 2706668885@qq.com
- Country
- China
- ProdList
- 4987
- Advantage
- 58
- Tel
- 027-87196173
- cusabio@163.com
- Country
- China
- ProdList
- 6066
- Advantage
- 58
- Tel
- 027-19371278702 18008634902
- 19384116026@163.com
- Country
- China
- ProdList
- 3008
- Advantage
- 58
- Tel
- Enzo Biochem Inc. 13797054060
- Enzoname@qq.com
- Country
- China
- ProdList
- 6174
- Advantage
- 58
- Tel
- 18886812933
- sales@biosynth.com
- Country
- China
- ProdList
- 6218
- Advantage
- 58
- Tel
- 21-80243558 86218024
- info@cellsignal.cn
- Country
- China
- ProdList
- 6427
- Advantage
- 58
- Tel
- 4006-123-828 13162017139
- market@ab-mart.com
- Country
- China
- ProdList
- 6917
- Advantage
- 58
- Tel
- 025-58868422
- info@sabbiotech.com
- Country
- China
- ProdList
- 6243
- Advantage
- 58
- Tel
- 51288865780
- sales@biosynth.com
- Country
- China
- ProdList
- 6051
- Advantage
- 58
- Tel
- 16615240262
- Info@leadingbiology.com
- Country
- China
- ProdList
- 6353
- Advantage
- 58