VAV1 antibody
Source Reactivity Background References- Product Name
- VAV1 antibody
- Chemical Name
- VAV1 antibody
- Synonyms
- VAV1 antibody;Mouse Monoclonal VAV1 Antibody
- CBNumber
- CB05704293
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb4426
- Product name
- VAV1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb4426
- Product name
- VAV1 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
VAV1 antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Mouse;Rat;Human
Background
Vav proteins belong to the Dbl family of guanine nucleotide exchange factors for Rho/Rac small GTPases. The three identified mammalian Vav proteins differ in their expression. Vav1 is expressed only in hematopoietic cells and is involved in the formation of the immune synapse. Vav2 and Vav3 are more ubiquitously expressed. Vav proteins contain the Dbl homology domain, which confers GEF activity, as well as protein interaction domains that allow them to function in pathways regulating actin cytoskeleton organization. Phosphorylation stimulates the GEF activity of Vav protein towards Rho/Rac.
References
[1] Hornstein, I. et al. (2004) Cell. Signal. 16, 1-11.
[2] Crespo, P. et al. (1997) Nature 385, 169-172.
[3] Han, J. et al. (1997) Mol. Cell. Biol. 17, 1346-1353.
VAV1 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
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