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LEM-14

Product Name
LEM-14
CAS No.
1814881-70-3
Chemical Name
LEM-14
Synonyms
LEM-14;LEM-14, 10 mM in DMSO;[1]Benzothieno[2,3-d]pyrimidin-4(1H)-one, 2-[[4-[[(3R)-3,4-dihydro-1-oxo-1H-2-benzopyran-3-yl]carbonyl]-1-piperazinyl]methyl]-5,6,7,8-tetrahydro-;5-({4-[(3R)-1-oxo-3,4-dihydro-1H-2-benzopyran-3-carbonyl]piperazin-1-yl}methyl)-8-thia-4,6-diazatricyclo[7.4.0.02,?]trideca-1(9),2(7),4-trien-3-one
CBNumber
CB05867413
Molecular Formula
C25H26N4O4S
Formula Weight
478.56
MOL File
1814881-70-3.mol
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LEM-14 Property

Boiling point:
788.3±70.0 °C(Predicted)
Density 
1.55±0.1 g/cm3(Predicted)
form 
Solid
pka
3.76±0.10(Predicted)
color 
Light brown to gray
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals
Product number
DC12562
Product name
LEM-14
Purity
>98%
Packaging
100mg
Price
$950
Updated
2021/12/16
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LEM-14 Chemical Properties,Usage,Production

Uses

LEM-14 is a potent NSD2 inhibitor with an IC50 of 132 μM. LEM-14 has the potential for the research of multiple myeloma[1].

References

[1] Shen Y, et al. Identification of LEM-14 inhibitor of the oncoprotein NSD2. Biochem Biophys Res Commun. 2019 Jan 1;508(1):102-108. DOI:10.1016/j.bbrc.2018.11.037

LEM-14 Preparation Products And Raw materials

Raw materials

Preparation Products

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LEM-14 Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58

1814881-70-3, LEM-14Related Search:


  • LEM-14
  • [1]Benzothieno[2,3-d]pyrimidin-4(1H)-one, 2-[[4-[[(3R)-3,4-dihydro-1-oxo-1H-2-benzopyran-3-yl]carbonyl]-1-piperazinyl]methyl]-5,6,7,8-tetrahydro-
  • 5-({4-[(3R)-1-oxo-3,4-dihydro-1H-2-benzopyran-3-carbonyl]piperazin-1-yl}methyl)-8-thia-4,6-diazatricyclo[7.4.0.02,?]trideca-1(9),2(7),4-trien-3-one
  • LEM-14, 10 mM in DMSO
  • 1814881-70-3