BAFF, HUMAN
Description Source Background- Product Name
- BAFF, HUMAN
- Chemical Name
- BAFF, HUMAN
- Synonyms
- HSBLYS;RHSBAFF;RHSTHANK;RHSZTNF4;RHSTALL-1;HUMAN BAFF;HUMAN BLYS;HUMAN THANK;BAFF, HUMAN;HUMAN ZTNF4
- CBNumber
- CB0664651
- Formula Weight
- 0
- MOL File
- Mol file
BAFF, HUMAN Property
- storage temp.
- −20°C
- form
- lyophilized powder
- biological source
- human
Safety
- WGK Germany
- 3
- Storage Class
- 13 - Non Combustible Solids
N-Bromosuccinimide Price
- Product number
- SRP3305
- Product name
- BAFF human
- Purity
- Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
- Packaging
- 20μG
- Price
- $423
- Updated
- 2025/07/31
- Product number
- B6681
- Product name
- BAFF, soluble human
- Purity
- >95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder
- Packaging
- 10μg
- Price
- $901
- Updated
- 2025/07/31
BAFF, HUMAN Chemical Properties,Usage,Production
Biological Activity
BAFF, a member of the TNF superfamily of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. Recombinant human soluble BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF.
Description
BAFF Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 153 amino acids and having a molecular mass of 17007 Dalton.
The BAFF is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
BAFF binds to tnfrsf13b/taci and tnfrsf17/bcma. Tnfsf13/april binds to the same 2 receptors, together, they form a 2 ligands -2 receptors pathway involved in the stimulation of b- and t-cell function and the regulation of humoral immunity. A third b-cell specific baff-receptor (baffr/br3) promotes the survival of mature b-cells and the b-cell response.
B Lymphocyte Stimulator functions as a potent B-cell growth factor in costimulation assays.
Administration of BAFF Human recombinant to mice disrupts splenic B-cell and T-cell zones and results in elevated levels of serum immunoglobulin.
BAFF, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
BAFF, HUMAN Suppliers
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