ChemicalBook > CAS DataBase List > H-LYS-LYS-PRO-TYR-ILE-LEU-OH

H-LYS-LYS-PRO-TYR-ILE-LEU-OH

Product Name
H-LYS-LYS-PRO-TYR-ILE-LEU-OH
CAS No.
139026-64-5
Chemical Name
H-LYS-LYS-PRO-TYR-ILE-LEU-OH
Synonyms
KKPYIL;LYS-LYS-PRO-TYR-ILE-LEU;[LYS8,9]-NEUROTENSIN (8-13);H-LYS-LYS-PRO-TYR-ILE-LEU-OH;(LYS8,LYS9)-NEUROTENSIN (8-13);Lys8,9]-Neurotensin (8-13),KKPYIL;[Lys8,9]-Neurotensin (8-13) - 5 mg;(lys-8-psi-ch2nh-lys9)-neurotensin*fragment 8-13;neurotensin, fragment 8-13, [Lys8-psi-(CH2NH)-Lys9];L-Leucine, L-lysyl-L-lysyl-L-prolyl-L-tyrosyl-L-isoleucyl-
CBNumber
CB0672069
Molecular Formula
C38H64N8O8
Formula Weight
760.96
MOL File
139026-64-5.mol
More
Less

H-LYS-LYS-PRO-TYR-ILE-LEU-OH Property

Boiling point:
1109.7±65.0 °C(Predicted)
Density 
1.203±0.06 g/cm3(Predicted)
storage temp. 
-15°C
pka
3.41±0.10(Predicted)
form 
Solid
color 
White to off-white
Sequence
H-Lys-Lys-Pro-Tyr-Ile-Leu-OH
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PEP0009203
Product name
(LYS8LYS9)-NEUROTENSIN(8-13)
Purity
95.00%
Packaging
1MG
Price
$606.38
Updated
2021/12/16
More
Less

H-LYS-LYS-PRO-TYR-ILE-LEU-OH Chemical Properties,Usage,Production

Uses

[Lys8, Lys9]-Neurotensin (8-13) (JMV438), a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, with Ki values of 0.33 nM and 0.95 nM for hNTS1 and hNTS2 receptors, respectively[1].

References

[1] Emilie Eiselt, et al. Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia. ACS Chem Neurosci. 2019 Nov 20;10(11):4535-4544. DOI:10.1021/acschemneuro.9b00390

H-LYS-LYS-PRO-TYR-ILE-LEU-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

H-LYS-LYS-PRO-TYR-ILE-LEU-OH Suppliers

China 64 France 1 The Netherlands 1 United States 7 Global 73
Brunschwig chemie
Tel
--
Fax
--
Email
brunschwig@brunschwig.nl
Country
The Netherlands
ProdList
4996
Advantage
67

139026-64-5, H-LYS-LYS-PRO-TYR-ILE-LEU-OHRelated Search:

(LYS9,TRP11,GLU12)-NEUROTENSIN (8-13) (CYCLIC ANALOG) NEUROTENSIN (9-13) NEUROTENSIN (1-11) (BOC-LYS9)-NEUROTENSIN (9-13)-METHYL ESTER NEUROTENSIN (1-8) (DAB9)-NEUROTENSIN (8-13) NEUROTENSIN AC-ARG-ARG-PRO-TYR-ILE-LEU-OH NEUROTENSIN (1-6) NEUROTENSIN (8-13) H-LYS-LYS-PRO-TYR-ILE-LEU-OH JMV 449 NEUROTENSIN

  • (lys-8-psi-ch2nh-lys9)-neurotensin*fragment 8-13
  • neurotensin, fragment 8-13, [Lys8-psi-(CH2NH)-Lys9]
  • KKPYIL
  • H-LYS-LYS-PRO-TYR-ILE-LEU-OH
  • [LYS8,9]-NEUROTENSIN (8-13)
  • (LYS8,LYS9)-NEUROTENSIN (8-13)
  • LYS-LYS-PRO-TYR-ILE-LEU
  • L-Leucine, L-lysyl-L-lysyl-L-prolyl-L-tyrosyl-L-isoleucyl-
  • Lys8,9]-Neurotensin (8-13),KKPYIL
  • [Lys8,9]-Neurotensin (8-13) - 5 mg
  • 139026-64-5
  • peptide