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2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE

Product Name
2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE
CAS No.
6127-18-0
Chemical Name
2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE
Synonyms
TOSLAB 23085;4-BroMo-2-Methylindole;4-BroMo-2-Methyl-1H-indole;1H-Indole,4-bromo-2-methyl-;2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE
CBNumber
CB0680068
Molecular Formula
C9H8BrN
Formula Weight
210.07
MOL File
Mol file
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2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE Property

storage temp. 
2-8°C
Appearance
Colorless to light yellow Liquid
InChI
InChI=1S/C9H8BrN/c1-6-5-7-8(10)3-2-4-9(7)11-6/h2-5,11H,1H3
InChIKey
MXRPXKYWAYTGJY-UHFFFAOYSA-N
SMILES
N1C2=C(C(Br)=CC=C2)C=C1C
CAS DataBase Reference
6127-18-0
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B697288
Product name
4-Bromo-2-methyl-1h-indole
Packaging
25mg
Price
$55
Updated
2021/12/16
TRC
Product number
B697288
Product name
4-Bromo-2-methyl-1h-indole
Packaging
100mg
Price
$145
Updated
2021/12/16
TRC
Product number
B697288
Product name
4-Bromo-2-methyl-1h-indole
Packaging
250mg
Price
$250
Updated
2021/12/16
TRC
Product number
B697288
Product name
4-Bromo-2-methyl-1h-indole
Packaging
50mg
Price
$95
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB141962
Product name
4-Bromo-2-methyl-1H-indole
Packaging
2g
Price
$818
Updated
2021/12/16
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2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE Chemical Properties,Usage,Production

Synthesis

1232861-11-8

6127-18-0

The general procedure for the synthesis of 4-bromo-2-methyl-1H-indole using the compound (CAS:1232861-11-8) as starting material was as follows: sodium hydroxide (4.01 g, 0.1 mol) was added to a mixture of methanol (80 mL) and water (40 mL) of intermediate 3 (7.0 g, 20.1 mmol). The reaction mixture was stirred at 50 °C for 6 hours. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure. The residue was extracted with dichloromethane (3 x 50 mL). The organic layers were combined, washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The residue was purified by fast column chromatography (silica gel as stationary phase, petroleum ether/ethyl acetate=5:1 as eluent) to afford the target product 4-bromo-2-methyl-1H-indole 4 (3.0 g, 71% yield). Low resolution mass spectrometry (LRMS) (M+H+) m/z: calculated value 209.98; measured value 210.12.

References

[1] Patent: WO2014/15291, 2014, A1. Location in patent: Page/Page column 186; 187
[2] Patent: US2010/160647, 2010, A1. Location in patent: Page/Page column 18-19
[3] Journal of Medicinal Chemistry, 2015, vol. 58, # 24, p. 9480 - 9497

2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE Suppliers

China 90 India 2 Russia 1 United Kingdom 1 United States 4 Global 98
Beijing YiboYuntian Technology Co., Ltd.
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13811826434
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lichen13811826434@126.com
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
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China
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Dtchem Laboratories,（Gan Su）Co.,Ltd.
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18993966060
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0943-8288977
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sales@techbiochem.com
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China
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Wuhan TCASChem Technology Co., Ltd.
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027-86697669 13986148687
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86-027-86697669
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sales@tcaschem.com
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China
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Shanghai Jian Chao Chemical Technology Co., Ltd.
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150-2103-5486 18017383231
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qq：2817624287
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983544897@qq.com
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China
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SynAsst Chemical.
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021-60343070
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021-35122006
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Wuhan Kaymke Chemical Co., Ltd.,
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027-027-87342388 18086026008
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027-87342388
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sales@kaymke.com
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China
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Shanghai Huikai Chemical Technology Co., Ltd.
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021-61995394 18916691159
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chemicalsea@163.com
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China
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Bide Pharmatech Ltd.
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400-164-7117 13681763483
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+86-21-61629029
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product02@bidepharm.com
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China
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39966
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Jiaxing Novartis Chemical Co., Ltd.
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18957373295
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China
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1580
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View Lastest Price from 2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
4-Bromo-2-methyl-1H-indole 6127-18-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-10

6127-18-0, 2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDERelated Search:

4-BroMo-2-Methyl-1,3-benzoxazole 4-BROMO-2-METHYL-1H-BENZIMIDAZOLE 4-BroMo-2-Methylbutan-2-ol 4-BroMo-2-MethylpyriMidine 4-Bromo-2-methoxypyrimidine 4-bromo-1-methylpyrazole-3-carboxy acid

  • 2-CYANO-N-(4-METHYLPHENYL)ETHANETHIOAMIDE
  • TOSLAB 23085
  • 1H-Indole,4-bromo-2-methyl-
  • 4-BroMo-2-Methyl-1H-indole
  • 4-BroMo-2-Methylindole
  • 6127-18-0