LIPOXIN B4
- Product Name
- LIPOXIN B4
- CAS No.
- 98049-69-5
- Chemical Name
- LIPOXIN B4
- Synonyms
- LXB4;LIPOXIN B4;5(S),14(R)-Lipoxin B4;UXVRTOKOJOMENI-WLPVFMORSA-N;5(S), 14(R), 15(S)-TRIHYDROXYEICOSA-6E,8Z,10E,12E-TETRAENOIC ACID;(5S,14R,15S)-5,14,15-Trihydroxy-(6E,8Z,10E,12E)-eicosatetraenoic acid;(5S,6E,8Z,10E,12E,14R,15S)-5,14,15-Trihydroxy-6,8,10,12-icosatetraenoic acid;(5S,6E,8Z,10E,12E,14R,15S)-5,14,15-trihydroxyicosa-6,8,10,12-tetraenoic acid;6,8,10,12-Eicosatetraenoic acid, 5,14,15-trihydroxy-, (5S,6E,8Z,10E,12E,14R,15S)-
- CBNumber
- CB0701080
- Molecular Formula
- C20H32O5
- Formula Weight
- 352.47
- MOL File
- 98049-69-5.mol
LIPOXIN B4 Property
- storage temp.
- -20°C
- solubility
- DMF: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >1 mg/ml (from 13(S)-HODE)
Safety
- Hazard Codes
- F,Xi
- Risk Statements
- 11-36/37/38
- Safety Statements
- 16-26-36
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 90420
- Product name
- Lipoxin B4
- Purity
- ≥95%
- Packaging
- 25μg
- Price
- $274
- Updated
- 2024/03/01
- Product number
- 90420
- Product name
- Lipoxin B4
- Purity
- ≥95%
- Packaging
- 50μg
- Price
- $519
- Updated
- 2024/03/01
- Product number
- 90420
- Product name
- Lipoxin B4
- Purity
- ≥95%
- Packaging
- 100μg
- Price
- $980
- Updated
- 2024/03/01
- Product number
- 396443
- Product name
- LXB4
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
- Product number
- L468770
- Product name
- 5(S),14(R)-LipoxinB4
- Packaging
- 50μg
- Price
- $600
- Updated
- 2021/12/16
LIPOXIN B4 Chemical Properties,Usage,Production
Uses
Lipoxins are a series of anti-inflammatory lipid mediators whose brief appearance generally signals the resolution of inflammation. Lipoxin A4 (LXA4) is a potent inhibitor of leukotriene (LT)-triggered polymorphonuclear neutrophil (PMN)-endothelial cell interaction and also blocks PMN migration stimulated by LTB4. LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 10-7 M, LXB4 inhibits PMN migration stimulated by LTB4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of ~3 X 10-10 M.
Uses
5(S),14(R)-Lipoxin B4 is a positional isomer of LXA4.
Definition
ChEBI: Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds. It has a role as a human metabolite. It is a lipoxin, a long-chain fatty acid and a hydroxy polyunsaturated fatty acid. It is a conjugate acid of a lipoxin B4(1-).