2-NITROFURAN Property

Melting point:

29-33 °C (lit.)

Boiling point:

84 °C/13 mmHg (lit.)

Density 

1.5808 (rough estimate)

refractive index 

1.4543 (estimate)

Flash point:

191 °F

storage temp. 

2-8°C

solubility 

Chloroform, Methanol

form 

Solid

color 

Clear Colorless to Off-White

Stability:

Stable. Incompatible with strong oxidizing agents.

CAS DataBase Reference

609-39-2

Safety

Hazard Codes 

Xn

Risk Statements 

20/21/22-40

Safety Statements 

7-23-36/37/39-45

RIDADR 

UN 1325 4.1/PG 2

WGK Germany 

3

RTECS 

LU3100000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H228Flammable solid

H351Suspected of causing cancer

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

2-NITROFURAN Chemical Properties,Usage,Production

Chemical Properties

solid

Uses

Nitrofurans are a class of broad-spectrum antibacterial compounds that are commonly added to water to destroy bacteria. However, nitrofurans have recently been withdrawn for use in the United States by the US Food and Drug Administration (FDA). Now, 2-nitrofuran is used as a minor antimicrobial in veterinary medicine.

Uses

2-NITROFURAN is a minor antimicrobial used in veterinary medicine.

Definition

ChEBI: 2-nitrofuran is a member of furans and a C-nitro compound.

Environmental Fate

2-Nitrofuran is a yellow crystalline solid with molecular weight of 113.07152 g mol^-1. The boiling point of 2-nitrofuran is 84 ℃ at 17 hPa and the melting point is 29–33 ℃. It is a flammable solid. Its flash point is 88 ℃ (closed cup). Vapor pressure is 0.398mmHg at 25 ℃. This compound is soluble in H2O and ethanol. Its density is 1.344 g cm^-3.
The partition behavior of 2-nitrofuran in water, sediment, and soil is 0.8. No data are available on its environmental persistency (degradation/speciation), long-range transport, bioaccumulation, and biomagnification. This chemical is stable but it is incompatible with strong oxidizing agents.

Toxicity evaluation

2-Nitrofuran reacts with DNA to form complexes, induces interstrand cross-links, produces alkali-labile lesions, and interferes with nucleic acid synthesis. Removal of the nitro group decreases the mutagenic activity.