5-Nitrofurfural
- Product Name
- 5-Nitrofurfural
- CAS No.
- 698-63-5
- Chemical Name
- 5-Nitrofurfural
- Synonyms
- 5-NITRO-2-FURALDEHYDE;AKOS B004244;Nitrofurfural;5-Nitrofurural;5-nitro-furfura;5-NITROFURFURAL;Furfural, 5-nitro-;5-NITROFURALDEHYDE;Niftyer Impurity 7;Nitrofuraldehyde,97%
- CBNumber
- CB2711562
- Molecular Formula
- C5H3NO4
- Formula Weight
- 141.08
- MOL File
- 698-63-5.mol
5-Nitrofurfural Property
- Melting point:
- 37-39 °C(lit.)
- Boiling point:
- 121 °C10 mm Hg(lit.)
- Density
- 1.349 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.59(lit.)
- Flash point:
- 92 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
- form
- Crystalline Low Melting Solid
- color
- Yellow to brown
- Water Solubility
- sparingly soluble
- Sensitive
- Air & Light Sensitive
- BRN
- 120539
- InChIKey
- SXINBFXPADXIEY-UHFFFAOYSA-N
- CAS DataBase Reference
- 698-63-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Furancarboxaldehyde, 5-nitro-(698-63-5)
Safety
- Hazard Codes
- F,Xi,Xn
- Risk Statements
- 11-68-10
- Safety Statements
- 16-36/37
- RIDADR
- UN 1325 4.1/PG 2
- WGK Germany
- 3
- RTECS
- LT7200000
- Hazard Note
- Irritant
- HazardClass
- 3.2
- PackingGroup
- III
- HS Code
- 29321900
- Hazardous Substances Data
- 698-63-5(Hazardous Substances Data)
N-Bromosuccinimide Price
- Product number
- 170968
- Product name
- 5-Nitro-2-furaldehyde
- Purity
- 99%
- Packaging
- 5g
- Price
- $85
- Updated
- 2024/03/01
- Product number
- 170968
- Product name
- 5-Nitro-2-furaldehyde
- Purity
- 99%
- Packaging
- 25g
- Price
- $163
- Updated
- 2024/03/01
- Product number
- N0387
- Product name
- 5-Nitro-2-furaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $37
- Updated
- 2024/03/01
- Product number
- N0387
- Product name
- 5-Nitro-2-furaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $105
- Updated
- 2024/03/01
- Product number
- A10618
- Product name
- 5-Nitro-2-furaldehyde, 99%
- Packaging
- 25g
- Price
- $133
- Updated
- 2024/03/01
5-Nitrofurfural Chemical Properties,Usage,Production
Description
Nitrofuran carboxaldehyde (NFC) is used to synthesize many drugs and chemicals such as nifuraldezone, puraguanidine, nifuratrone, furmethoxadone, etc. Furfural the main structure of NFC was determined many years ago to be a byproduct of formic acid synthesis. Furfural is produced from agricultural byproducts such as sugarcane bagasse and corncobs.
Chemical Properties
Yellow to brown crystalline low melting solid
Uses
NFC and its derivatives have antibacterial and antifungal activities. They destroy both gram-positive and gram-negative organisms such as Staphylococcus aureus, Salmonella schotmuelleri, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and Streptococcus pyogenes. They may be used as antibacterial agents in a prophylactic manner, for example, in cleaning and disinfecting products. This compound also has antitrichomonal and antifungal activities.
Uses
5-Nitro-2-furaldehyde was used in the synthesis of a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives. . It was also used in the synthesis of modified mesoporous silica (MCM-41). 5-Nitrofurfural can be commonly used as pharmaceutical intermediates.
Definition
ChEBI: 5-Nitrofurfural is a C-nitro compound and a member of furans.
Production Methods
Furfural is nitrated in acetic anhydride solution at 25 – 40 ℃ to give the diacetate [92-55-7], which is purified by recrystallization from isopropanol and then used directly for the production of derived drugs.
Toxicity evaluation
NFC inhibits the uptake of oxygen and disrupts cellular respiration within mitochondria. NFC and other nitrofurans are relatively potent inhibitors of monoamine oxidase enzyme in mammalian and avian species.
5-Nitrofurfural Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Nitrofurfural manufacturers
- Product
- 5-Nitrofurfural 698-63-5
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 605
- Release date
- 2019-09-01
- Product
- 5-Nitrofurfural 698-63-5
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 621
- Release date
- 2019-09-01