S-2 METHANANDAMIDE

Product Name: S-2 METHANANDAMIDE
CAS No.: 157182-48-4
Chemical Name: S-2 METHANANDAMIDE
Synonyms: S-2 METHANANDAMIDE;S-2 Methanandamide Exclusive;(S)-(+)-ARACHIDONOYL-2'-HYDROXY-1'-PROPYLAMIDE;N-(2S-HYDROXYPROPYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;N-(2-HYDROXYPROPYL)-, [S-(ALL-Z)]-5,8,11,14-EICOSATETRAENAMIDE;(5Z,8Z,11Z,14Z)-N-[(2S)-2-hydroxypropyl]icosa-5,8,11,14-tetraenamide;5,8,11,14-Eicosatetraenamide, N-[(2S)-2-hydroxypropyl]-, (5Z,8Z,11Z,14Z)-
CBNumber: CB0722735
Molecular Formula: C23H39NO2
Formula Weight: 361.56
MOL File: Mol file

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S-2 METHANANDAMIDE Property

Boiling point:: 529.0±50.0 °C(Predicted)
Density: 0.935±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: ≤10mg/ml in DMSO;10mg/ml in dimethyl formamide
form: solution in ethanol.
pka: 14.55±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 90076
Product name: S-2 Methanandamide
Purity: ≥98%
Packaging: 5mg
Price: $53
Updated: 2024/03/01

Cayman Chemical

Product number: 90076
Product name: S-2 Methanandamide
Purity: ≥98%
Packaging: 10mg
Price: $96
Updated: 2024/03/01

Cayman Chemical

Product number: 90076
Product name: S-2 Methanandamide
Purity: ≥98%
Packaging: 25mg
Price: $214
Updated: 2024/03/01

ApexBio Technology

Product number: C5513
Product name: S-2Methanandamide
Packaging: 25mg(solution)
Price: $243
Updated: 2021/12/16

AK Scientific

Product number: 3066DF
Product name: (5Z,8Z,11Z,14Z)-N-(2-Hydroxypropyl)icosa-5,8,11,14-tetraenamide
Packaging: 25mg
Price: $336
Updated: 2021/12/16

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S-2 METHANANDAMIDE Chemical Properties,Usage,Production

Uses

S-2 methanandamide is the second most potent CB1 receptor agonist in the methanandamide series. It has a Ki value of 26 nM for the CB1 receptor. S-2 methanandamide is also less prone to FAAH inactivation and inhibits the murine vas deferens twitch response with an IC50 value of 47 nM.

Biological Activity

s-2 methanandamide is a cb1 receptor ligand.the cannabinoid receptor type 1 (cb1), is a g protein-coupled cannabinoid receptor located mainly in the central and peripheral nervous system. cb1 is also expressed in several cells relating to metabolism, such as muscle cells, fat cells, liver cells, and the digestive tract. the cb1 receptor has been involved in the maintenance of homeostasis in health and disease, preventing the development of excessive neuronal activity, reducing pain and other inflammatory symptoms. enhanced receptor expression has been identified in human hepatocellular carcinoma tumor samples and human prostate cancer cells [2].s-2 methanandamide was the second most potent cb1 receptor agonist in the methanandamide series. s-2 methanandamide activated the cb1 receptor with a ki value of 26 nm. s-2 methanandamide was less prone to faah inactivation. s-2 methanandamide inhibited the murine vas deferens twitch response with an ic50 value of 47 nm.

References

[1] abadji v, lin s, taha g, et al. (r)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability[j]. journal of medicinal chemistry, 1994, 37(12): 1889-1893.
[2] howlett a c. cannabinoid receptor signaling[m]//cannabinoids. springer berlin heidelberg, 2005: 53-79.

S-2 METHANANDAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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S-2 METHANANDAMIDE Suppliers

CHINA 9 Switzerland 1 United States 2 Global 12

Absin Bioscience Inc.

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157182-48-4, S-2 METHANANDAMIDERelated Search:

ANANDAMIDE

(S)-(+)-ARACHIDONOYL-2'-HYDROXY-1'-PROPYLAMIDE

S-2 METHANANDAMIDE

N-(2-HYDROXYPROPYL)-, [S-(ALL-Z)]-5,8,11,14-EICOSATETRAENAMIDE

N-(2S-HYDROXYPROPYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE

S-2 Methanandamide Exclusive

(5Z,8Z,11Z,14Z)-N-[(2S)-2-hydroxypropyl]icosa-5,8,11,14-tetraenamide

5,8,11,14-Eicosatetraenamide, N-[(2S)-2-hydroxypropyl]-, (5Z,8Z,11Z,14Z)-

157182-48-4